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Immunoregulation in Idiopathic Inflammatory Myopathies: From
Immunoregulation in Idiopathic Inflammatory Myopathies: From

... innate immune system through activation of the type I IFN system and TLR pathway in addition to the adaptive immune response6,13,18. Type I IFN-induced genes and proteins are upregulated in blood and muscle from PM and DM6,19. However, the exact source of type I IFN remains unclear because pDC, a ma ...
Methods S1.
Methods S1.

... contraction, no visible movement; 2. Movement but only with gravity; 3. Movement against gravity; 4. Movement against resistance but weaker than normal; 5. Normal power. The total score was calculated as the sum of the individual muscle group scores for each of the 22 muscles, i.e., total score rang ...
Preview
Preview

... 1. tip of tongue-drains into submental lymph nodes. 2. remaining anterior 2/3-drains into submandibular and deep cervical lymph nodes on both sides. 3. posterior 1/3-drains into deep cervical lymph nodes on both sides. CARDIAC MUSCLE FIBERS-make up the myocardium (thick, middle layer of the heart). ...
Cervical-Instability-Handout
Cervical-Instability-Handout

... • History of trauma or congenital/systemic disease • Neck pain • Intolerance to prolonged positions • Feeling need to support the head • Sharp pain or catch with movements ...
Introduction to Biology II
Introduction to Biology II

... due to myelin loss and secondary axonal damage. Myasthenia gravis is a disorder of neuromuscular transmission leading to fluctuating weakness and fatigue. Weakness is caused by circulating antibodies that block (Receptor_antagonist) acetylcholine receptors at the neuromuscular junction. Opsoclonus m ...
Immunopathology
Immunopathology

...  The destruction of targets too large to be phagocytosed, such as parasites or tumor cells. ...
PANDAS and PANS - Kennedy Krieger Institute
PANDAS and PANS - Kennedy Krieger Institute

... PANDAS is an abbreviation for Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections. This term is used to describe a subset of children and adolescents who have Obsessive Compulsive Disorder (OCD) and/or tic disorders, an in whom symptoms worsen following a strep i ...
Autoimmune Disorders
Autoimmune Disorders

... • More than 80 types of autoimmune disorders affect 5% of the population • Immune system turns its defense against body’s own tissues → B and T cells react against ‘self’ ...
Rheumatoid Arthritis
Rheumatoid Arthritis

... – AA being affected 3x more than any other race (and more severely) ...
PPT
PPT

... Histamine Antagonism  Physiologic Antagonism:  Epinehrine ...
Non-Toxic material Reusable
Non-Toxic material Reusable

... Snoring is the vibration of respiratory structures and the resulting sound due to obstructed air movement during breathing while sleeping. While sleeping muscles of the throat relaxes. When this happens, your airway narrows causing snoring In some cases the sound may be soft, but in other cases, it ...
Branched-chain amino acids with added L
Branched-chain amino acids with added L

... and suppress the rise in creatine kinase and lactate dehydrogenase after exercise, suggesting an inhibitory effect on the breakdown of muscle protein.1-3 Moreover, due to the increased oxidation of BCAAs during endurance exercise, athletes may have higher requirements for these nutrients than sedent ...
Rheumatology
Rheumatology

... percent of cases. Anti-DsDNA titers are not very high. Type III: Focal proliferative is a severe form than Mesangial form and is present in 10-20 percent of cases. Urinalysis shows proteinuria and hematuria and serum creatinine is elevated. Histopathology shows proliferative changes with some areas ...
The antibody in real life
The antibody in real life

... So it appears we are going full circle creating more and more vaccines to stimulate the immune system to produce anti-bodies via B-cell stimulation and now with the formation of autoimmune disorders researchers are desperately trying to dampen down the B-cell responses. So the pre-occupation of vacc ...
Major functions of the immune system
Major functions of the immune system

... B cells are coated with immunoglobulins : give them the ability to recognize that foreign proteins and stimulate an antigen-antibody reaction. The immunoglobulins are usually all present during an immune response, but in varying amounts depending on the specific antigen involved and the overall heal ...
Consultant Urological Surgeon Benenden Hospital Tunbridge Wells
Consultant Urological Surgeon Benenden Hospital Tunbridge Wells

... Imaging of the Upper Urinary Tract Chronic retention Haematuria Recurrent infection Sterile pyuria Profound symptoms or pain ...
Chapter 1 - SCHSPE34
Chapter 1 - SCHSPE34

... Contrast water therapy • involves subjecting the body to alternate periods of how and cold water based on alternating vascular vasodilation and vasoconstriction and promoting increased blood flow which will: • increase removal of wastes from working muscles • increase supply of oxygen and fuels to w ...
Respiratory infections
Respiratory infections

... • Causes local destruction of cilia, interferes with normal airway clearance which leads to mechanical irritation and persistent cough • Acts as a super antigen stimulating PNM’s and macrophages to release cytokines (TNF, IL1, and IL 6) ...
The Head & Neck - Karbala Medical College / Anatomy
The Head & Neck - Karbala Medical College / Anatomy

... sternocleidomastoid muscle during a difficult labour. Hemorrhage occurs into the muscle and may be detected as a small, rounded tumour during early weeks after birth. Later, it is replaced by fibrous tissue, which contracts and shortens the muscle pulling mastoid process down toward sternoclavicular ...
Chalazion Removal A chalazion, from a Greek word meaning `small
Chalazion Removal A chalazion, from a Greek word meaning `small

... located in the upper and lower eyelids. The inflammation is in reaction to trapped oil secretions. While it isn't caused by bacteria, the site can become infected if not treated. A chalazion may occur on an upper or lower eyelid. It may be red, swollen and sore. It can sometimes cause the eyelid to ...
Cryptogenic organising pneumonia or acute fibrinous and organising pneumonia?
Cryptogenic organising pneumonia or acute fibrinous and organising pneumonia?

... upregulation of cytokines involved in the process of angiogenesis, a review dealing with the immune response to resistive breathing may present the angiogenetic response as well. Exercise training induces a series of adaptive responses in the cardiovascular and skeletal muscular system, including my ...
Common Sports Medicine Medical Conditions
Common Sports Medicine Medical Conditions

... 1. A minimum of 72 hours of topical therapy is required for skin lesions 2. A minimum of two weeks of systemic antifungal therapy is required for scalp lesions. 3. Wrestlers with extensive and active lesions will be disqualified. Activity of treated lesions can be judged either by use of KOH prepara ...
Common Sports Medicine Medical Conditions
Common Sports Medicine Medical Conditions

... 1. A minimum of 72 hours of topical therapy is required for skin lesions 2. A minimum of two weeks of systemic antifungal therapy is required for scalp lesions. 3. Wrestlers with extensive and active lesions will be disqualified. Activity of treated lesions can be judged either by use of KOH prepara ...
Qi Mail - Needles and Tea
Qi Mail - Needles and Tea

... Under normal conditions, an immune response cannot be triggered against the cells of one's own body. In certain cases, however, immune cells make a mistake and attack the very cells that they are meant to protect. This can lead to a variety of autoimmune diseases which encompass a broad category of ...
NM-70 Certificate Number
NM-70 Certificate Number

... Using the infrared rays that penetrate deep into tissue, fat cells can literally melt away by a cessation of sauna temperature, 60-70 C. In parallel with the copious perspiration which thus appears also run toxins out of your body. As a bonus, you get better looking skin, because of impurities and w ...
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Myasthenia gravis

Myasthenia gravis (from Greek μύς ""muscle"", ἀσθένεια ""weakness"", and Latin: gravis ""serious""; abbreviated MG) is a neuromuscular disease that leads to fluctuating muscle weakness and fatigue. In the most common cases, muscle weakness is caused by circulating antibodies that block acetylcholine receptors at the postsynaptic neuromuscular junction, inhibiting the excitatory effects of the neurotransmitter acetylcholine on nicotinic receptors at neuromuscular junctions. Alternatively, in a much rarer form, muscle weakness is caused by a genetic defect in some portion of the neuromuscular junction that is inherited at birth as opposed to developing through passive transmission from the mother's immune system at birth or through autoimmunity later in life.Myasthenia is treated with medications such as acetylcholinesterase inhibitors or immunosuppressants, and, in selected cases, thymectomy (surgical removal of the thymus gland). The disease is diagnosed in 3 to 30 people per million per year. Diagnosis is becoming more common due to increased awareness.
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