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Functional Neutropenia
Functional Neutropenia

... These patients should receive initial oral or IV empirical antibiotic doses in a clinic or hospital setting; They may be transitioned to outpatient oral or IV treatment if they meet specific clinical criteria (Changing to the oral regimen is recommended when they become afebrile after 3 days of trea ...
Role of Neutrophils in Dengue Patients: Clearance of Dengue Virus
Role of Neutrophils in Dengue Patients: Clearance of Dengue Virus

... activate platelets causing platelet dysfunctions and thrombocytopenia, a hallmark of severe dengue disease. Activated platelet-neutrophil interactions have been well established, and yet its role in the pathogenic cause of dengue remains poorly understood. Forty seven acute dengue confirmed patients ...
PRE TEST - cloudfront.net
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... 12. Sharing clothes will not put someone at risk for getting pubic lice (crabs). 13. Syphilis has various stages. 14. All STD’s can be cured with antibiotics. 15. A viral STD can be cured. 16. Chlamydia is one of the most common STD’s. 17. As long as you don’t see the Herpes blisters on a person, a ...
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Outbreak Management Checklist

... Factors to be considered in the decision to convene an OCT include: (a) the type of communicable disease involved - In the case of possible healthcare associated transmission of a blood borne virus a critical incident team should be set up - see guidelines at http://www.health.qld.gov.au/chrisp/ic_g ...
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Gompf's ID Pearls 3.0
Gompf's ID Pearls 3.0

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... usually not necessary. However, workers with significant occupational risk of exposure to hepatitis B should have a blood test four to eight weeks after completing their course of vaccination to confirm that they have adequate protection. Workers who fail to respond to hepatitis B vaccination may ga ...
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Vaccines: Essential Weapons in the Fight Against Disease

... of whom were healthy and vibrant before an infectious disease led them to their graves. Fortunately, that world no longer exists because of tremendous progress made in vaccine development and application. There are now more than two dozen vaccines that can prevent death or disability from infectious ...
Guidelines for Research Involving Viral Vectors
Guidelines for Research Involving Viral Vectors

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... coursework. Unvaccinated students should initiate the hepatitis B vaccine series prior to or during their first semester at MUSC. Previously immunized students must provide proof of the primary hepatitis B series (3 vaccines) AND a Quantitative Hepatitis B surface Antibody titer (preferably drawn 4- ...
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Chapter 14: Principles of Disease

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Basic Disease Investigation in Colorado

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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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