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140
140

... presentation of viral peptides by MHC class I and II; these may persist and remain hidden from the immune system [12]. These viral peptides and/or tissue antigens altered by the virus may induce an atypical immune response. The concept of epitope spreading, whereby the tissue damage from a primary i ...
STDs - Wsfcs
STDs - Wsfcs

... o Contact with infected blood – HIV and hepatitis B o Skin to skin contact with an infected area or sore – herpes or genital warts STDs also spread easily because you can't tell whether someone has an infection. o Some people with STDs don't even know that they have them. These people are in danger ...
Type III Hypersensitivity
Type III Hypersensitivity

... although IgM may also be involved. This form of hypersensitivity has a lot in common with type I except that the antibody involved is IgG and therefore not prebound to mast cells, so that only preformed complexes can bind to the low affinity Fcgamma RIII. The antigen is soluble and not attached to t ...
Compatibility of plasmids expressing different antigens in a single
Compatibility of plasmids expressing different antigens in a single

... method to generate protective immunity against multiple pathogens. Unfortunately, many vaccines cannot be mixed because of physical incompatibilities. DNA vaccines are thought to be ideal for multivalent vaccines because of their similarity of form. Experiments described in this paper represent the ...
Immunodeficiencies
Immunodeficiencies

... • Lymphomas, myelomas, CLL ...
Infection_Control_Lecture_PP
Infection_Control_Lecture_PP

... – Private room if possible, if not, place in room with person who has same infection. – Maintain distance of at least 3 feet between the beds. – Wear surgical mask when working within 3 feet of infected person. – If you must take infected person outside room, have him or her wear surgical mask. ...
Bacteria and Viruses
Bacteria and Viruses

... replicates in a host cell, it destroys the host cell. • Copies of the virus are then released into the host organism, where they can infect other cells. • As viruses replicate, their DNA or RNA frequently mutates, enabling them to adjust to changes in their host cell. ...
Anti-Chlamydia trachomatis IIFT EUROIMMUN IIFT Infectious Serology
Anti-Chlamydia trachomatis IIFT EUROIMMUN IIFT Infectious Serology

... Indications: Test system for the in vitro determination of antibodies against Chlamydia trachomatis in human serum or plasma for the diagnosis of the following diseases: trachoma, urogenital tract infections and lymphogranuloma venereum. Clinical significance: The infectious agent Chlamydia trachoma ...
Pathophysiology Multiple Organ Dysfunction Syndrome
Pathophysiology Multiple Organ Dysfunction Syndrome

... TNF-a, IL-1, IL-6, IFN ...
The Concept of Virus
The Concept of Virus

... Until the end of the nineteenth century the history of viruses is just a part of the history of infectious diseases. In about 2500 B.C. the Chinese had identified small-pox and knew that it was transmissible. To write however without comment, as some people do, that the Chinese knew viral diseases i ...
The Concept of Virus
The Concept of Virus

... Until the end of the nineteenth century the history of viruses is just a part of the history of infectious diseases. In about 2500 B.C. the Chinese had identified small-pox and knew that it was transmissible. To write however without comment, as some people do, that the Chinese knew viral diseases i ...
SkinLecture
SkinLecture

... Can evolve from localized skin abscesses (boils) or within sites of preexisting trauma. The margin of the ecthyma ulcer can be indurated, raised, and violaceous. Untreated ecthymatous lesions can enlarge over the course of weeks or months to a diameter of 2 to 3 cm. Staphylococcal and streptococcal ...
Effects of gastrointestinal nematode infection on the
Effects of gastrointestinal nematode infection on the

... response to infection can vary significantly depending upon the activation of different types of lymphokine-secreting cells. In mice these two subsets are referred to as Thl (standing for T helper cell 1) and Th2 cells. These distinct subsets of T helper cells produce distinct arrays of lymphokines ...
presentation_Haijun5-15-2009-19-4-50
presentation_Haijun5-15-2009-19-4-50

... • Family-wise error rates (also FDR in this case) of Fisher’s exact text unadjusted for multiplicity and Poisson regression with mixture prior are compared • Percentage of simulated datasets yielding Y=0, 1, 2 or ≥3 incorrectly flagged adverse events out of 464 PTs are ...
Klasifikasi, Kodifikasi Penyakit 2 Pertemuan 8
Klasifikasi, Kodifikasi Penyakit 2 Pertemuan 8

... threatening. They ecompass many causes of food poisoning and travelers diarrhea as well as serious diseases such as typhoid fever and cholera. Protozoal infections includes gardiasis and amebiasis. Intestinal worm infestations are exceedingly common worldwide (round worms, tapeworms), includes pinwo ...
1088-3818-1-SM
1088-3818-1-SM

... Medicinal plants have been traditionally used for different kinds of ailments including infectious diseases of bacterial and viral origin. There is an increasing need for search of new compounds with antiviral activity due to the problems of viral resistance, viral latency and recurrent infection in ...
WHO Advisory Committee on Variola Virus Research Report of the Fifth Meeting
WHO Advisory Committee on Variola Virus Research Report of the Fifth Meeting

... established coded DNA panels, including variola virus DNA and other orthopoxvirus DNA samples, for the evaluation of viral DNA identification assays. The Committee recommended that these methodologies be made available to all Member States that request them. ...
Genital and Perirectal Herpes Simplex Virus Infection
Genital and Perirectal Herpes Simplex Virus Infection

... B. The majority of genital and perirectal herpetic outbreaks in the U.S. are caused by HSV-2, although up to 10-50% of first episodes are due to HSV-1. HSV-1 may be increasing as a cause of first episode genital herpes in women, 16-21 year old persons and in certain population groups, particularly i ...
Influence of congenital human cytomegalovirus infection and the
Influence of congenital human cytomegalovirus infection and the

... Vertical transmission of HCMV during pregnancy is considered the most common cause of congenital infection worldwide, affecting ∼0.2–2% of infants and potentially causing fetal lesions [8–10]. Though most infected newborns are asymptomatic, ∼10% display a variety of clinical disorders [8, 11] potent ...
specific disease exclusion guidelines for childcare
specific disease exclusion guidelines for childcare

... Until all blisters have dried into scabs; usually by day 6 after the rash began. Chickenpox can occur even if someone has had the varicella vaccine. These are referred to as breakthrough infections. Breakthrough infections develop more than 42 days after vaccination, are usually less severe, have an ...
Genital and Perirectal Herpes Simplex Virus Infection
Genital and Perirectal Herpes Simplex Virus Infection

... B. The majority of genital and perirectal herpetic outbreaks in the U.S. are caused by HSV-2, although up to 10-50% of first episodes are due to HSV-1. HSV-1 may be increasing as a cause of first episode genital herpes in women, 16-21 year old persons and in certain population groups, particularly i ...
Summary of Infectious Complications Occurring
Summary of Infectious Complications Occurring

Respiratory Diseases in Horses - OSU Fact Sheets
Respiratory Diseases in Horses - OSU Fact Sheets

... or to recurrent airway obstruction (heaves). Some of the lining may actually slough and result in multiple areas of denuded respiratory tract lining. Most horses will be infectious for at least five days after onset of clinical illness. The length of time the virus is excreted will vary among horses ...
anaerobes_Yin
anaerobes_Yin

... (toxin B). Toxin A causes the disruption of intercellular tight junctions followed by altered membrane permeability and fluid secretion. Toxin B causes destruction of the cellular cytoskeleton. The precise role that each toxin plays in the pathogenesis of the disease is still unclear, but the two to ...
INFECTION CONTROL POLICY AND PROCEDURES University of
INFECTION CONTROL POLICY AND PROCEDURES University of

... o Should be worn when there is potential contact with blood or bodily fluids, when a patient’s skin is non-intact, when the clinician has an open wound/non-intact skin, or when handling items or conducting procedures noted accordingly under the work practice procedure guidelines. o Proper Gloving Pr ...
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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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