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sample standard operating procedures for cervical cancer screening
sample standard operating procedures for cervical cancer screening

... Note: If the walls of the vagina are very lax, use a cotton swab to push away any tissue protruding between the blades of the speculum. Alternatively, prior to insertion of the speculum, a condom can be rolled over the blades and the tip of the condom cut off. When the speculum is inserted and the b ...
Vaccinia - UCSF Office of Research
Vaccinia - UCSF Office of Research

... Minor complications are generalized vaccinia with multiple lesions, benign rash, or secondary infection. Complications are serious for those with eczema or who are immunocompromised. Death is most often the result of post-vaccinial encephalitis or progressive vaccinia. Several infections of laborato ...
Bloodborne Pathogens
Bloodborne Pathogens

... The federal Bloodborne Pathogens Rule is found in the Code of Federal Regulations at Title 29, Section 1910.1030, and is enforced by the Occupational Safety and Health Administration, or OSHA. This rule requires employers with workers who might be exposed to bloodborne pathogens in the workplace to ...
Jenner Newsletter May 2010
Jenner Newsletter May 2010

... should induce effective B cell responses and T cell responses at the same time. Nature does not provide an example of a protective immune response since no-one has ever been confirmed to have successfully cleared HIV-1 infection. Therefore, both of these goals present substantial challenges which ne ...
Initial Phase of Infection with Tyzzer`s Organism in
Initial Phase of Infection with Tyzzer`s Organism in

... methods of Seglen (1976) and Arnheiter (1980) as already described (Kawamura et al., 1983b). Primary monolayers of 24 to 30 h culture were obtained by seeding 1.5 or 3.5 ml of cell suspension in culture medium (CM) containing 3.5 x lo5 viable cells ml-I in 35 or 60 mm plastic dishes, respectively. C ...
The Generalized Rash: Diagnostic and Treatment Considerations
The Generalized Rash: Diagnostic and Treatment Considerations

... • Systemic steroids ameliorate psoriasis only while taking them, with resultant rebound • Systemic steroids will lead to muted inflammation/diagnostic clues on skin biopsy • Topical and systemic steroids will cause tinea to persist and worsen • Extensive scabies is better managed with combination of ...
L1 L2 Examining of respiratory system. Upper respiratory tract
L1 L2 Examining of respiratory system. Upper respiratory tract

... (r/o transmission of upper respiratory stertor) which suggests the presence of fluid or exudate in larger airways, as with bronchitis or pneumonia. • Wheezes (sibilant rhonchi) are high-pitched expiratory sounds typical of bronchial narrowing. The usual associations are bronchial disease (bronchitis ...
Is it Influenza or Pneumonia . . .or Both?
Is it Influenza or Pneumonia . . .or Both?

Gold, M.C., M.W. Munks, M. Wagner, C.W. McMahon, A. Kelly, D.G. Kavanagh, M.K. Slifka, U.H. Koszinowski, D.H. Raulet, and A.B. Hill. 2004. Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response. J Immunol 172:6944-6953. 
Gold, M.C., M.W. Munks, M. Wagner, C.W. McMahon, A. Kelly, D.G. Kavanagh, M.K. Slifka, U.H. Koszinowski, D.H. Raulet, and A.B. Hill. 2004. Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response. J Immunol 172:6944-6953. 

... sometimes aborted at the immediate-early (IE) phase of gene expression, and at other times presumably progressing to replication (33, 34). However, unless mice are immunosuppressed, replicating virus is not detectable, and even the latent virus DNA load is near or below the threshold of detection, e ...
clostridium difficile disease
clostridium difficile disease

... water, as well as hand sanitization with alcohol-based gels.1 ...
54 year old male with fever, altered mental status
54 year old male with fever, altered mental status

... Thought to be a type III hypersensitivity reaction against the drug or metabolite One suggested mechanism is hypersensitivity to the drug as a hapten with an CSF-protein which would explain the limitation of the inflammation to only the central nervous system. Some patients have idiosyncratic reacti ...
Potential Role of Bordetella Pertussis in Celiac Disease
Potential Role of Bordetella Pertussis in Celiac Disease

... drop in BP rates. Of the many Swedish childhood vaccination programs tracked from 1980-2000, the only disease for which vaccine coverage increased as infant CD declined in the 1990s, was BP [10]. ...
Introduction - Beck-Shop
Introduction - Beck-Shop

... recorded but, over the 3-year period, of 13 000 enrolled hoplites (soldiers), 4400 died — a mortality rate of 33%. Hagnon took the fleet and sailed to Potidaea carrying the plague there also and this made dreadful havoc among the Athenian troops. Even those who had been there previously and had been ...
Alhatlani et al 2015 Virus Research
Alhatlani et al 2015 Virus Research

Custom-Engineered  Chimeric  Foot-and-Mouth  Disease  Vaccine
Custom-Engineered Chimeric Foot-and-Mouth Disease Vaccine

... chimeric virus, vKNP/SAT2, was engineered by replacing the external capsid-coding region (1B-1D/2A) of an infectious cDNA clone of the SAT2 vaccine strain, ZIM/7/83, with that of the SAT1 virus KNP/196/91. The vKNP/SAT2 virus exhibited comparable infection kinetics, virion stability and antigenic pr ...
Complications associated with central venous access device in
Complications associated with central venous access device in

... 1994 and May 2012 and treated in the participating centres, and who required of CVAD insertion during the follow-up period. Our national policy is to insert CVAD very early for primary prophylaxis. A CVAD was inserted in the majority (87%; 78 of 90; 72 of 74 with severe and 6 of 16 with moderate hae ...
Central nervous system borreliosis mimicking a pontine tumour
Central nervous system borreliosis mimicking a pontine tumour

... enhancement of the lesion (Fig. 1). Although this finding could not exclude a malignant tumour, the differential diagnosis was broadened to include inflammatory and infectious causes. Blood count and serum inflammatory markers were within normal limits. Examination of cerebrospinal fluid (CSF), howe ...
What is the Human Papilloma Virus (HPV) Infection?
What is the Human Papilloma Virus (HPV) Infection?

... a group of more than 100 related viruses, some of which cause a type of growth called a papilloma, or more commonly known aswarts. HPV can infect cells on the surface of the skin, genitals, anus, mouth and throat, but not the blood or most internal organs such as the heart or lungs. Doctors believe ...
ppt
ppt

... • Define: a paradoxical deterioration in clinical status attributable to the recovery of the immune system during HAART • Pathophysiology – Rapid fall in viral load – Increase in immune effector cells – Functional T cell immunity return ...
antigenic characterization of polish infectious bursal disease virus
antigenic characterization of polish infectious bursal disease virus

... early Polish viruses. Indeed, these isolates did not react with Mabs 3 and 4 and the two latter viruses also reacted poorly, if at all, with Mabs 5 and 8. Hence, the neutralizing epitopes present on the early Polish IBDVs were clearly different in comparison with both the European F52/70 reference s ...
West Nile Virus - Nicholas Kurek`s Portfolio
West Nile Virus - Nicholas Kurek`s Portfolio

... and door screens, and reducing peridomestic mosquito breeding sites, can further decrease the risk for WNV exposure. Blood and some organ donations in the United States are screened for WNV infection; health care professionals should remain vigilant for the possible transmission of WNV through blood ...
Conventional and molecular detection of Newcastle disease and
Conventional and molecular detection of Newcastle disease and

... the birds may have fibrotic or cystic bursa of Fabricius that become atrophied prematurely (before six months of age) and may die of infections by agents that would not usually cause disease in immunocompetent birds (The Merck Veterinary Manual. 2006). The postmortem findings were haemorrhages in th ...
Ebola Virus Disease - National Home Infusion Association
Ebola Virus Disease - National Home Infusion Association

... Recommendations—Known or Suspected EVD • Current CDC recommendations focus on the hospital setting,  however the recommendations for personal protective  equipment (PPE) and environmental infection control  measures are applicable to any healthcare setting • Healthcare personnel (HCP) refers to… – A ...
What Are Sexually Transmitted Diseases?
What Are Sexually Transmitted Diseases?

... diseases (STDs) are said to be a “silent epidemic”. Identify why teenagers are particularly at risk for being infected with STDs. List steps you can take to prevent the spread of STDs. ...
Egyptian H5N1 Influenza Viruses—Cause for Concern?
Egyptian H5N1 Influenza Viruses—Cause for Concern?

... ‘‘Herfst virus’’; the other, T314I, affected HA stability [12]). Although the Herfst and Imai studies used different experimental strategies and tested viruses of HA/H5 clade 2 or 1, respectively, the results were remarkably similar: the transmissible mutant H5 viruses bound to human-type receptors, ...
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Hepatitis B



Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) which affects the liver. It can cause both acute and chronic infections. Many people have no symptoms during the initial infection. Some develop a rapid onset of sickness with vomiting, yellowish skin, feeling tired, dark urine and abdominal pain. Often these symptoms last a few weeks and rarely does the initial infection result in death. It may take 30 to 180 days for symptoms to begin. In those who get infected around the time of birth 90% develop chronic hepatitis B while less than 10% of those infected after the age of five do. Most of those with chronic disease have no symptoms; however, cirrhosis and liver cancer may eventually develop. These complications results in the death of 15 to 25% of those with chronic disease.The virus is transmitted by exposure to infectious blood or body fluids. Infection around the time of birth or from contact with other people's blood during childhood is the most frequent method by which hepatitis B is acquired in areas where the disease is common. In areas where the disease is rare, intravenous drug use and sexual intercourse are the most frequent routes of infection. Other risk factors include working in healthcare, blood transfusions, dialysis, living with an infected person, travel in countries where the infection rate is high, and living in an institution. Tattooing and acupuncture led to a significant number of cases in the 1980s; however, this has become less common with improved sterility. The hepatitis B viruses cannot be spread by holding hands, sharing eating utensils, kissing, hugging, coughing, sneezing, or breastfeeding. The infection can be diagnosed 30 to 60 days after exposure. Diagnosis is typically by testing the blood for parts of the virus and for antibodies against the virus. It is one of five known hepatitis viruses: A, B, C, D, and E.The infection has been preventable by vaccination since 1982. Vaccination is recommended by the World Health Organization in the first day of life if possible. Two or three more doses are required at a later time for full effect. This vaccine works about 95% of the time. About 180 countries gave the vaccine as part of national programs as of 2006. It is also recommended that all blood be tested for hepatitis B before transfusion and condoms be used to prevent infection. During an initial infection, care is based on the symptoms that a person has. In those who develop chronic disease antiviral medication such as tenofovir or interferon maybe useful, however these drugs are expensive. Liver transplantation is sometimes used for cirrhosis.About a third of the world population has been infected at one point in their lives, including 240 million to 350 million who have chronic infections. Over 750,000 people die of hepatitis B each year. About 300,000 of these are due to liver cancer. The disease is now only common in East Asia and sub-Saharan Africa where between 5 and 10% of adults have chronic disease. Rates in Europe and North America are less than 1%. It was originally known as serum hepatitis. Research is looking to create foods that contain HBV vaccine. The disease may affect other great apes as well.
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