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Role of tumour necrosis factor (TNF)
Role of tumour necrosis factor (TNF)

... the infectious focus, wild-type mice given antibodies effectively neutralising TNF can no longer contain mycobacterial growth within the lesions, and granuloma breakdown is followed by dissemination of mycobacteria.27 28 Lymphotoxin (LT) α, LTβ, and the recently identified LIGHT (homologous to lymph ...
A REVIEW ON PNEUMONIC PASTEURELLOSIS (RESPIRATORY
A REVIEW ON PNEUMONIC PASTEURELLOSIS (RESPIRATORY

... Mohamed, R. A. & E. B. Abdelsalam, 2008. A review on pneumonic pasteurellosis (respiratory mannheimiosis) with emphasis on pathogenesis, virulence mechanisms and predisposing factors. Bulg. J. Vet. Med., 11, No 3, 139−160. Pneumonic pasteurellosis is one of the most economically important infectious ...
The diagnostic significance of relative bradycardia in infectious
The diagnostic significance of relative bradycardia in infectious

... of infectious diseases. Relative bradycardia may be used to differentiate infectious diseases in selected clinical situations. Unfortunately, pulse-temperature differences have been vaguely described in a variety of publications and textbooks, leading to confusion on the part of clinicians in how to ...
Trichinella spiralis
Trichinella spiralis

... During this phase, the adult worms mate and then the male worms die. The adult females penetrate the mucosa of the intestine and produces larvae. The females will produce approximately 1,500 larvae over the next four to sixteen weeks and then die. The larvae enter a muscle fiber and form a fibroblas ...
Chapter 2 Review
Chapter 2 Review

... D. wearing goggles, gloves, a gown, and a mask. Rationale: This PPE is selected according to manner in which a communicable disease is spread. ...
PDF printable version of Appendix 4: Commonly asked questions
PDF printable version of Appendix 4: Commonly asked questions

Pathogenic Roles, Industrial Uses and Medicinal Prospects of
Pathogenic Roles, Industrial Uses and Medicinal Prospects of

... significant genetic differences were observed between animal and human PCR ribotype 012 and 014 isolates. The authors concluded that toxinogenic C. difficile PCR ribotypes found in animals correspond to PCR ribotypes associated with human disease in hospitalized patients in the Netherlands (Koene et ...
Mumps FAQs
Mumps FAQs

... A: Mumps is a viral disease transmitted by airborne or direct contact with infected droplets or saliva from an infected person. Humans are the only known host of the mumps virus. Q: I had contact with some people who have been diagnosed mumps. What are the symptoms of mumps? A: The symptoms of mumps ...
- Wiley Online Library
- Wiley Online Library

... E-mail: [email protected] ...
compro manton
compro manton

... been made in the use of various preparations for different species of animals against diverse spectrum of parasites. The relative success of these drugs depends on their ease of administration, extension of action after administration and period and/or frequency of application based on the epidemiol ...
Academy of Breastfeeding Medicine Founder`s Lecture 2008
Academy of Breastfeeding Medicine Founder`s Lecture 2008

... of TGFBR III and hence intestinal responsiveness to TGF-β2 are confined to the neonatal period when the intestine is exposed to TGF-β2 in breastmilk.45 There are also data indicating that breastmilk may contain soluble TGFBR III and thus provides the infant with the receptor necessary for optimal re ...
press kit - Sanofi Pasteur
press kit - Sanofi Pasteur

... The innovative dengue vaccine with proven efficacy against all four types of dengue is the culmination of over two decades of scientific innovation and collaboration, including 25 clinical studies in 15 countries around the world. Over 40,000 volunteers participated in the clinical study program, wh ...
Bad Bug Book - Michigan State University Extension
Bad Bug Book - Michigan State University Extension

... Each chapter in this book is about a pathogen – a bacterium, virus, or parasite – or a natural toxin that can contaminate food and cause illness. The book was prepared by the Food and Drug Administration (FDA) and contains scientific and technical information about the major pathogens that cause the ...
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... before and after the introduction of the rotavirus vaccine in four Latin American countries. Vaccine 2013 ;31 :C99-C108. Lanzieri TM, Costa I, Shafi FA, et al. Trends in hospitalizations from all-cause gastroenteritis in children younger than 5 years of age in Brazil before and after human rotavirus ...
another threat on the
another threat on the

... The first symptomatic case of the Zika fever in a human was recorded in Nigeria in 1954 [18]. Until 2007 only 14 cases of the disease were confirmed worldwide [17]. The first outbreak of the Zika fever occurred in Micronesia (Yap Island) in 2007. During the outbreak Duffy et al. [17] collected blood ...
Smallpox vaccination and all-cause infectious disease
Smallpox vaccination and all-cause infectious disease

... pertussis and hepatitis B may increase mortality unrelated to the target disease.2,3 Though initially based on observational studies, these unexpected findings are now being reproduced in randomized controlled trials designed to investigate the non-specific effects of vaccination.4,5,7 For example, ...
A brief history of prions - Oxford Academic
A brief history of prions - Oxford Academic

The role of seafood in foodborne diseases in the
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... increases dramatically within shellfish, suggesting a protective relationship ( 5 , 1 2 1 ) . In the USA, Shigella was implicated in 111 shellfish-related cases and four outbreaks from 1 8 9 8 to 1 9 9 0 ( 1 0 1 ) . Shigella may be an important potential disease agent as it has a low infectious dose ...
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... suspected or identified. The impact of infections on nursing home practices begins with the admitting process of screening for infection. Following the admission screening, the nursing home must have systems in place to manage the care to the resident with an infection. Managing the infection includ ...
29/2013 - Repatriation Medical Authority
29/2013 - Repatriation Medical Authority

... received by the particular organ or tissue. The formula used to calculate the cumulative equivalent dose allows doses from multiple types of ionising radiation to be combined, by accounting for their differing biological effect. The unit of equivalent dose is the sievert. For the purposes of this St ...
MYCOPLASMA RESPIRATORY DISEASE COMPLEX IN FEEDLOT CATTLE IN SOUTH AFRICA
MYCOPLASMA RESPIRATORY DISEASE COMPLEX IN FEEDLOT CATTLE IN SOUTH AFRICA

... Bovine respiratory disease complex (BRD) consists of a largely single clinical entity of bronchopneumonia that is usually associated with the assembly of large numbers of especially weaner cattle into a feedlot environment. It has a multifactorial aetiology and develops as a result of complex intera ...
The War Against MRSA
The War Against MRSA

... Associated Invasive Infections due to MRSA have been reduced by more than 54.2% between 2005 and 2011. • Community associated infections have decreased by only 5%. (Laidman, 2013) ...
Alleged Nanobacteria Exist and Participate in Calcification of Arterial
Alleged Nanobacteria Exist and Participate in Calcification of Arterial

... apatite at non-saturating levels of calcium and phosphate. Cisar did not follow saturation degree analysis in his studies although saliva is known to be highly super-saturated with calcium and phosphate. Yet Cisar suggested as an alternative explanation nanobacteria to be replicating apatite mineral ...
A Mathematical Model of Human Papillomavirus
A Mathematical Model of Human Papillomavirus

What causes tonsillitis?
What causes tonsillitis?

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African trypanosomiasis



African trypanosomiasis or sleeping sickness is a parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei. There are two types that infect humans, Trypanosoma brucei gambiense (T.b.g) and Trypanosoma brucei rhodesiense (T.b.r.). T.b.g causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas.Initially, in the first stage of the disease, there are fevers, headaches, itchiness, and joint pains. This begins one to three weeks after the bite. Weeks to months later the second stage begins with confusion, poor coordination, numbness and trouble sleeping. Diagnosis is via finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first and second stage disease.Prevention of severe disease involves screening the population at risk with blood tests for T.b.g. Treatment is easier when the disease is detected early and before neurological symptoms occur. Treatment of the first stage is with the medications pentamidine or suramin. Treatment of the second stage involves: eflornithine or a combination of nifurtimox and eflornithine for T.b.g. While melarsoprol works for both it is typically only used for T.b.r. due to serious side effects.The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. As of 2010 it caused around 9,000 deaths per year, down from 34,000 in 1990. An estimated 30,000 people are currently infected with 7000 new infections in 2012. More than 80% of these cases are in the Democratic Republic of the Congo. Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin and two in 1920 and 1970 in several African countries. Other animals, such as cows, may carry the disease and become infected.
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