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Renal involvement in tropical infections
Renal involvement in tropical infections

... related to direct infection of the kidneys and urinary tract or indirect consequence of systemic effects of infection (Table 1, 2). Direct invasion of the tubules in the kidney and resultant tubulointerstitial inflammation leading to AKI has been demonstrated in patients infected with leptospirosis ...
Moving beyond averages: Individual
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... This body of work constitutes an integral part of epidemiological theory, and provides valuable tools to address many important questions—particularly those where mechanisms of disease spread, or disease control, are linked to identifiable types of individuals. However, for the present task of quant ...
HSII 2.02 Classes of Microorganisms
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... Fungi – organisms that usually enjoy a symbiotic, but sometimes parasitic relationship with their host – provide numerous drugs and foods – provide bubbles in bread, champagne, and beer – cause a number of plant and animal diseases – fungal diseases are very difficult to treat ...
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... respiratory and digestive tracts into the feces, getting into water and spreading to water fowl. Dr. Balkovic then described human flu outbreaks that occurred over the last century. The original flu we worried about was Spanish flu, the 1918 H1 pandemic. The identity of the causative virus was unkno ...
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...  Most cases are subclinical, some get respiratory infection with flu-like symptoms  In < 1% of cases (due to predisposing factors, such as fatigue, poor nutrition, etc.): progressive, disseminated disease form resembling TB  Diagnosis: serological tests ...
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Guide To Canine Denistry
Guide To Canine Denistry

... edge of the tooth. The pus can also add a yellow colour to saliva. Presence of this pus emphasises the extent of the infection that is associated with dental disease. Often a far greater number of bacteria are present in dental disease than if the pus was collected as an abscess. Whilst an abscess w ...
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African trypanosomiasis



African trypanosomiasis or sleeping sickness is a parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei. There are two types that infect humans, Trypanosoma brucei gambiense (T.b.g) and Trypanosoma brucei rhodesiense (T.b.r.). T.b.g causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas.Initially, in the first stage of the disease, there are fevers, headaches, itchiness, and joint pains. This begins one to three weeks after the bite. Weeks to months later the second stage begins with confusion, poor coordination, numbness and trouble sleeping. Diagnosis is via finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first and second stage disease.Prevention of severe disease involves screening the population at risk with blood tests for T.b.g. Treatment is easier when the disease is detected early and before neurological symptoms occur. Treatment of the first stage is with the medications pentamidine or suramin. Treatment of the second stage involves: eflornithine or a combination of nifurtimox and eflornithine for T.b.g. While melarsoprol works for both it is typically only used for T.b.r. due to serious side effects.The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. As of 2010 it caused around 9,000 deaths per year, down from 34,000 in 1990. An estimated 30,000 people are currently infected with 7000 new infections in 2012. More than 80% of these cases are in the Democratic Republic of the Congo. Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin and two in 1920 and 1970 in several African countries. Other animals, such as cows, may carry the disease and become infected.
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