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Immunoglobulin Reactivity to Pneumococcal Serotypes
Immunoglobulin Reactivity to Pneumococcal Serotypes

... What does it cause?  Causes pneumonia, meningitis and systemic sepsis.  Prevalent in individuals at the extremes of age  1 million deaths are accountable to pneumococcal infections worldwide ...
No Slide Title
No Slide Title

... Her FVC was 70% predicted and DLCO 57% predicted. She began oral corticosteroid therapy without significant symptomatic improvement (red flag). Six months prior to admission, the patient had continued dypsnea and a transthoracic ultrasound and right heart catheterization showed the presence of pulmo ...
The Eye Red
The Eye Red

... HSV blepharitis is encountered primarily in children, although adults may also manifest this disorder. Presenting symptoms include pain and tenderness upon palpation, as well as increased lacrimation in severe cases. Swollen pre-auricular nodes on the involved side is common. ...
Important properties of epidemics and endemic situations
Important properties of epidemics and endemic situations

... For a highly infectious disease (R0 large) and a not so effective vaccine (E not too close to 1) vc might exceed 1. This means vaccination alone cannot prevent an outbreak! More on modelling and inference of vaccine effects later in course ...
fatigue2009 - Dr. Ngo Minh
fatigue2009 - Dr. Ngo Minh

... • Fatigue: Feeling of lack of energy, tiredness, weariness described by patients as exhaustion. It is often accompanied by subjective sensation of weakness and strong desire to rest or sleep. May or not associated with other symptoms Remember: fatigue is a symptom NOT a disease ...
Xenodiagnosis of Leishmania donovani in BALB/c mice using
Xenodiagnosis of Leishmania donovani in BALB/c mice using

... on human volunteers showed that Brazilian VL cases were infectious to feeding sand fly females while volunteers who were asymptomatic, were not [8]. However, in this study, asymptomatic infections were identified using LST that detects only late-stage cell-mediated immunity [9]. Hence, these LST pos ...
Dyspepsia - ACM
Dyspepsia - ACM

... *cannot discriminate between active & previous infection (therefore, do not use to diagnose recurrence) ...
Clinical Syndromes/Conditions with Required Level or Precautions
Clinical Syndromes/Conditions with Required Level or Precautions

... No person-to-person transmission, except by blood transfusion. See Haemorrhagic Fevers ...
Molecular Koch`s postulate
Molecular Koch`s postulate

the PDF here
the PDF here

... Despite improving therapies [8], our study found that deaths associated with HCV continued to rise while deaths associated with 60 ONNICs that are routinely reported to CDC declined. The great decline among deaths associated with HIV, pneumococcal disease, and tuberculosis from the ONNICs category w ...
Canadian Tuberculosis Standards - Canadian Respiratory Guidelines
Canadian Tuberculosis Standards - Canadian Respiratory Guidelines

... and to favour the middle and lower lung zones, which receive most of the ventilation.2 In immunocompetent hosts, it is theorized that alveolar macrophages ingest the M. tuberculosis organisms and may or may not destroy them, depending on the degree to which phagocytosing cells are nonspecifically ac ...
Rapid risk assessment - European Centre for Disease Prevention
Rapid risk assessment - European Centre for Disease Prevention

... schistosomiasis is a disease caused by Schistosoma haematobium of tropical and inter-tropical zones. The disease is endemic in several areas in Africa, Madagascar and the Middle East. The route of infection for humans is skin exposure to parasite-infested fresh water during routine occupational, rec ...
What Are Communicable Diseases?
What Are Communicable Diseases?

... After a virus penetrates a cell (called the host cell), the virus takes control of the cell to manufacture more viruses. The new viruses burst from the cell, usually killing it, and take over other cells. Viruses usually run their course and eventually are killed by the immune system. Antibiotics do ...
Chronic Disease Management Programs and
Chronic Disease Management Programs and

... program also offers a variety of services for these patients taking into account all the evidencebased practices that are effective in the self-management of the chronic illnesses such as congestive heart failure, ischemic heart disease, epilepsy, Chronic Obstructive Pulmonary Disease, Congestive He ...
von Willebrand disease
von Willebrand disease

... mutations may be as high as 1 to 2% of the population, The clinical and laboratory manifestations of vWD are extremely heterogeneous, and diagnosis can sometimes be difficult. ...
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Oct 12 Lecture 12 Evolution of Virulence

... Many observations are consistent with the conventional wisdom: Legionnaire’s disease, Lyme disease, Ebola fever, and SARS are consequences of human infection with symbionts of other species that have recently jumped into humans ...
What is Dengue?1
What is Dengue?1

... behind the eyes, severe joint and muscle pain (hence the name “break-bone fever”, often used to describe the disease) , nausea, vomiting, and skin rash. Some cases develop much milder symptoms, which can be mistaken for a flu or other viral infection. Symptoms of the disease last 6-8 days. Fever usu ...
A short review of hemorrhagic fever with renal syndrome
A short review of hemorrhagic fever with renal syndrome

... Hemorrhagic fevers have attracted more and more attention of Public Health Authorities, as an emerging pathogenic virus in the past decades.1 China is in the top of list, with 30,000-50,000 cases reported annually, which account for >90% of total numbers worldwide. This disease is found throughout t ...
PATHOGENICITY OF CZECH ISOLATES OF INFECTIOUS BURSAL
PATHOGENICITY OF CZECH ISOLATES OF INFECTIOUS BURSAL

... compare the characteristics of the isolates using standard methods of assessment of lymphatic organs index, lesion scoring, immunosuppressive effects, and haematological parameters. Materials and Methods Chickens purchased from a controlled flock (Striped Leghorns, Czech Academy of Sciences, Prague) ...
DEVICE RELATED NOSOCOMIAL INFECTION IN ICU
DEVICE RELATED NOSOCOMIAL INFECTION IN ICU

... - Replacement of administration sets and intravenous fluids - Clean injection parts with 70% alcohol or povidone-iodine before accessing the system - Do not use filters routinely for infection control purposes - Do not administer anti-microbials routinely before insertion or during use of an intrav ...
Lec.9 Intestinal sporozoa
Lec.9 Intestinal sporozoa

... completes its life cycle through the stages of asexual generation (schizogony) and sexual generation (gametogony) in a single host .All these stages of the parasite are truly intracellular and are being surrounded by a host cell membrane, which is extracytoplasmic. Man acquires infection on ingesti ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... Disease occurrence is more in rainy season and occurs in persons who engage in occupational or recreational behavior that brings them into contact with mite-infested habitats.[3] The disease presents as an acute febrile illness with non-specific signs and symptoms.[4] In our study, the commonest pre ...
Gastrointestinal Bleeding
Gastrointestinal Bleeding

... Careful ENT exam to rule out causes that can mimic upper GI bleeds. Proper abdominal exam and rectal exam. ...
Classification of Water-Related Disease
Classification of Water-Related Disease

... requirement for nutrition and overall health, with a corresponding wide range of diseases that can be classified as having a water component. All the agents involved have other means of transmission and the evidence that confirms a water association can be elusive, often depending on whether a large ...
Diarrhoea
Diarrhoea

... Straining during at least 25% of defecations Lumpy or hard stools in at least 25% of defecations Sensation of incomplete evacuation for at least 25% of defecations Sensation of anorectal obstruction/blockage for at least 25% of defecations Manual maneuvers to facilitate at least 25% of defecations ( ...
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African trypanosomiasis



African trypanosomiasis or sleeping sickness is a parasitic disease of humans and other animals. It is caused by protozoa of the species Trypanosoma brucei. There are two types that infect humans, Trypanosoma brucei gambiense (T.b.g) and Trypanosoma brucei rhodesiense (T.b.r.). T.b.g causes over 98% of reported cases. Both are usually transmitted by the bite of an infected tsetse fly and are most common in rural areas.Initially, in the first stage of the disease, there are fevers, headaches, itchiness, and joint pains. This begins one to three weeks after the bite. Weeks to months later the second stage begins with confusion, poor coordination, numbness and trouble sleeping. Diagnosis is via finding the parasite in a blood smear or in the fluid of a lymph node. A lumbar puncture is often needed to tell the difference between first and second stage disease.Prevention of severe disease involves screening the population at risk with blood tests for T.b.g. Treatment is easier when the disease is detected early and before neurological symptoms occur. Treatment of the first stage is with the medications pentamidine or suramin. Treatment of the second stage involves: eflornithine or a combination of nifurtimox and eflornithine for T.b.g. While melarsoprol works for both it is typically only used for T.b.r. due to serious side effects.The disease occurs regularly in some regions of sub-Saharan Africa with the population at risk being about 70 million in 36 countries. As of 2010 it caused around 9,000 deaths per year, down from 34,000 in 1990. An estimated 30,000 people are currently infected with 7000 new infections in 2012. More than 80% of these cases are in the Democratic Republic of the Congo. Three major outbreaks have occurred in recent history: one from 1896 to 1906 primarily in Uganda and the Congo Basin and two in 1920 and 1970 in several African countries. Other animals, such as cows, may carry the disease and become infected.
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