Inhaled and intranasal fluticasone propionate and haematoma
... vulnerability of blood vessels because of a decreased collagen turnover due to an inhibition of fibrocyte function [4]. A relation between use of ICS and occurrence of easy bruising has clearly been demonstrated, just like a relationship between bruising and adrenal suppression [9]. Although a direc ...
... vulnerability of blood vessels because of a decreased collagen turnover due to an inhibition of fibrocyte function [4]. A relation between use of ICS and occurrence of easy bruising has clearly been demonstrated, just like a relationship between bruising and adrenal suppression [9]. Although a direc ...
Tramadol and hiccups
... Hiccups (singultus) are involuntary, brief contractions of the diaphragm, followed by a sudden closure of the glottis. The pathophysiology of hiccups is unknown. Hiccups can be acute or persistent. In most cases acute hiccups disappear spontaneously. Persistent hiccups may continue for more than 48 ...
... Hiccups (singultus) are involuntary, brief contractions of the diaphragm, followed by a sudden closure of the glottis. The pathophysiology of hiccups is unknown. Hiccups can be acute or persistent. In most cases acute hiccups disappear spontaneously. Persistent hiccups may continue for more than 48 ...
analysis of yellow card reporting: annual report for 2008-2012
... members of the public through the Yellow Card Scheme. Reports are also submitted as a legal requirement by pharmaceutical companies holding Marketing Authorisations (MAHs). Information collected through the Yellow Card Scheme is an important means of monitoring drug safety in clinical practice, acti ...
... members of the public through the Yellow Card Scheme. Reports are also submitted as a legal requirement by pharmaceutical companies holding Marketing Authorisations (MAHs). Information collected through the Yellow Card Scheme is an important means of monitoring drug safety in clinical practice, acti ...
study
... events during their hospital stays that resulted in temporary harm. Temporary harm events are those that require intervention but do not cause lasting harm. Although many cases represent fairly minor occurrences, such as hypoglycemia, others were classified as temporary harm only because the patient ...
... events during their hospital stays that resulted in temporary harm. Temporary harm events are those that require intervention but do not cause lasting harm. Although many cases represent fairly minor occurrences, such as hypoglycemia, others were classified as temporary harm only because the patient ...
PUBLIC ASSESSMENT REPORT Decentralised Procedure
... Packaging area for blistering and cartooning process, when applicable. The proposed storage conditions and shelf life of two years without special storage condition can accepted. ...
... Packaging area for blistering and cartooning process, when applicable. The proposed storage conditions and shelf life of two years without special storage condition can accepted. ...
Prevalence and nature of adverse drug events and the potential for
... bibliographic databases until 2010 (n=5770) were used as data sources, in addition to regional and national registers. ADEs were categorised into adverse drug reactions (ADRs), drug intoxications from overdose, drug dependence and abuse, sub-therapeutic effects of drug therapy (STEs), and morbiditie ...
... bibliographic databases until 2010 (n=5770) were used as data sources, in addition to regional and national registers. ADEs were categorised into adverse drug reactions (ADRs), drug intoxications from overdose, drug dependence and abuse, sub-therapeutic effects of drug therapy (STEs), and morbiditie ...
Chapter 12: Emergency Medications
... • Animal studies have not demonstrated a fetal risk but there are no controlled studies in women or • Animal reproductive studies have shown an adverse effect that was not confirmed in controlled studies on women in the first trimester ...
... • Animal studies have not demonstrated a fetal risk but there are no controlled studies in women or • Animal reproductive studies have shown an adverse effect that was not confirmed in controlled studies on women in the first trimester ...
Petition for a Writ of Certiorari
... was proposed by the drug’s manufacturer—an astonishing position premised on the SJC’s apparent belief that FDA’s decisionmaking hinges on the identity of the party that proposed new warning language rather than the proposal’s scientific merits. Neither rule has any basis in Wyeth or common sense. Wy ...
... was proposed by the drug’s manufacturer—an astonishing position premised on the SJC’s apparent belief that FDA’s decisionmaking hinges on the identity of the party that proposed new warning language rather than the proposal’s scientific merits. Neither rule has any basis in Wyeth or common sense. Wy ...
Options for Unsolicited Reporting
... Assistance (BJA) included adoption of unsolicited reporting as a priority consideration for states seeking funding under the Harold Rogers Prescription Drug Monitoring Program.3 The CDC recommended that “state prescription drug monitoring programs should routinely send reports to providers on patien ...
... Assistance (BJA) included adoption of unsolicited reporting as a priority consideration for states seeking funding under the Harold Rogers Prescription Drug Monitoring Program.3 The CDC recommended that “state prescription drug monitoring programs should routinely send reports to providers on patien ...
Switching from propranolol to metoprolol
... metoprolol answers are found in the Davis's Drug Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web. metoprolol succinate (Toprol XL) 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day ; New York Heart Association (NYHA) class ≥II. Metoprolol ...
... metoprolol answers are found in the Davis's Drug Guide powered by Unbound Medicine. Available for iPhone, iPad, Android, and Web. metoprolol succinate (Toprol XL) 25 mg PO qDay initially; increased every 2 weeks PRN; target dosage, 200 mg/day ; New York Heart Association (NYHA) class ≥II. Metoprolol ...
Understanding the relation between adverse events, patient
... and roles and responsibilities within the care teams (including patients, informal caregivers and formal care providers) and how this impacts safety for team communication, handoffs, and knowledge transfer amongst the team. Efforts to examine safety in home care should emphasize the minimization or ...
... and roles and responsibilities within the care teams (including patients, informal caregivers and formal care providers) and how this impacts safety for team communication, handoffs, and knowledge transfer amongst the team. Efforts to examine safety in home care should emphasize the minimization or ...
Prednisolone and hiccups Introduction
... and intercostal muscles. There are numerous causes of hiccups. Hiccups are usually caused by gastric distention from overeating or carbonated beverages. Other causes include gastrointestinal disorders, thoracic disorders or cardiac disorders. Hiccups may also be drug-related. In rare cases, hiccups ...
... and intercostal muscles. There are numerous causes of hiccups. Hiccups are usually caused by gastric distention from overeating or carbonated beverages. Other causes include gastrointestinal disorders, thoracic disorders or cardiac disorders. Hiccups may also be drug-related. In rare cases, hiccups ...
Adverse_Events_White_Paper
... “person-time” is beneficial for clarity. The use of the EAIR is generally more appropriate for AESIs or for signal detection when there are differential dropouts between treatments, but would need to be used with caution (see Section 10.9). Program safety analysis plan (PSAP): A compound-level plann ...
... “person-time” is beneficial for clarity. The use of the EAIR is generally more appropriate for AESIs or for signal detection when there are differential dropouts between treatments, but would need to be used with caution (see Section 10.9). Program safety analysis plan (PSAP): A compound-level plann ...
The Egyptian Guideline for Medical Device Vigilance System
... It is critically important that the safety and performance of medical devices are continually assessed when they are in use i.e. post-marketing, as the information collected during the pre-marketing phase is incomplete with regard to adverse incidents and this is mainly because: No amount of rigor ...
... It is critically important that the safety and performance of medical devices are continually assessed when they are in use i.e. post-marketing, as the information collected during the pre-marketing phase is incomplete with regard to adverse incidents and this is mainly because: No amount of rigor ...
1.1. Oxaliplatin and laryngospasm Introduction Oxaliplatin (Eloxatin
... Brandi et al [3] described hypersensitivity reactions related to oxaliplatin. Laryngospasm is mentioned as severe form of a hypersensitivity reaction. A total of 17 patients with hypersensitivity reactions were described, two of them experienced laryngospasm after their second and third infusion num ...
... Brandi et al [3] described hypersensitivity reactions related to oxaliplatin. Laryngospasm is mentioned as severe form of a hypersensitivity reaction. A total of 17 patients with hypersensitivity reactions were described, two of them experienced laryngospasm after their second and third infusion num ...
Management of Significant Adverse Events and Reviews Supporting
... Medication error – wrong drug, wrong dose, wrong patient, wrong time, wrong rate, wrong preparation or wrong route of administration Haemolytic reaction due to the administration of incompatible blood Unexpected significant hypo or hyperglycaemia occurring in the ...
... Medication error – wrong drug, wrong dose, wrong patient, wrong time, wrong rate, wrong preparation or wrong route of administration Haemolytic reaction due to the administration of incompatible blood Unexpected significant hypo or hyperglycaemia occurring in the ...
E2C (R2) Step 5 Periodic benefit-risk evaluation - EMA
... important findings occur – and periodically – to allow an overall assessment of the accumulating data. Although the majority of new information will be safety-related, new information about effectiveness, limitations of use, alternative treatments, and many other aspects of the drug’s place in thera ...
... important findings occur – and periodically – to allow an overall assessment of the accumulating data. Although the majority of new information will be safety-related, new information about effectiveness, limitations of use, alternative treatments, and many other aspects of the drug’s place in thera ...
Ondansetron and the Risk of Cardiac Arrhythmias: A Systematic
... The primary outcome was the number of reports describing an arrhythmia after single oral ondansetron dose administration. Secondary outcomes included (1) cases linking the administration of ondansetron by any route, dose, and frequency to the development of an arrhythmia; and (2) the strength of cau ...
... The primary outcome was the number of reports describing an arrhythmia after single oral ondansetron dose administration. Secondary outcomes included (1) cases linking the administration of ondansetron by any route, dose, and frequency to the development of an arrhythmia; and (2) the strength of cau ...
The following are pertinent excerpts from the report prepared by
... iron, for the hematologic improvement of patients with anemia caused by uterine bleeding associated with leiomyomas (tumors of uterine smooth muscle). In men, Lupron is indicated for the palliative management of advanced prostate carcinoma. In children, Lupron is indicated for the treatment of centr ...
... iron, for the hematologic improvement of patients with anemia caused by uterine bleeding associated with leiomyomas (tumors of uterine smooth muscle). In men, Lupron is indicated for the palliative management of advanced prostate carcinoma. In children, Lupron is indicated for the treatment of centr ...
The following are pertinent excerpts from the report prepared by
... iron, for the hematologic improvement of patients with anemia caused by uterine bleeding associated with leiomyomas (tumors of uterine smooth muscle). In men, Lupron is indicated for the palliative management of advanced prostate carcinoma. In children, Lupron is indicated for the treatment of centr ...
... iron, for the hematologic improvement of patients with anemia caused by uterine bleeding associated with leiomyomas (tumors of uterine smooth muscle). In men, Lupron is indicated for the palliative management of advanced prostate carcinoma. In children, Lupron is indicated for the treatment of centr ...
The following are pertinent excerpts from the report
... iron, for the hematologic improvement of patients with anemia caused by uterine bleeding associated with leiomyomas (tumors of uterine smooth muscle). In men, Lupron is indicated for the palliative management of advanced prostate carcinoma. In children, Lupron is indicated for the treatment of centr ...
... iron, for the hematologic improvement of patients with anemia caused by uterine bleeding associated with leiomyomas (tumors of uterine smooth muscle). In men, Lupron is indicated for the palliative management of advanced prostate carcinoma. In children, Lupron is indicated for the treatment of centr ...
Retrospective Review of 456930 Doses
... occurred from 2002 to 2006. All IV doses administered in the outpatient, inpatient, and emergency departments of our tertiary referral center were included. Demographic data and information regarding the type of adverse effect, severity of the effect, treatment, and outcome were obtained from the cl ...
... occurred from 2002 to 2006. All IV doses administered in the outpatient, inpatient, and emergency departments of our tertiary referral center were included. Demographic data and information regarding the type of adverse effect, severity of the effect, treatment, and outcome were obtained from the cl ...
Frequency and Severity of Adverse Effects of Iodinated
... occurred from 2002 to 2006. All IV doses administered in the outpatient, inpatient, and emergency departments of our tertiary referral center were included. Demographic data and information regarding the type of adverse effect, severity of the effect, treatment, and outcome were obtained from the cl ...
... occurred from 2002 to 2006. All IV doses administered in the outpatient, inpatient, and emergency departments of our tertiary referral center were included. Demographic data and information regarding the type of adverse effect, severity of the effect, treatment, and outcome were obtained from the cl ...
Regulation of Subsequent Entry Biologics
... sale in Canada, with “demonstrated similarity” to that previously authorized biologic.1 The biologic to which the SEB is compared is called a “reference biologic drug.” The demonstrated similarity referred to in the definition of an SEB relates to similarity in the quality attributes of the two biol ...
... sale in Canada, with “demonstrated similarity” to that previously authorized biologic.1 The biologic to which the SEB is compared is called a “reference biologic drug.” The demonstrated similarity referred to in the definition of an SEB relates to similarity in the quality attributes of the two biol ...
Bisphosphonates And blurred vision
... Bisphosphonates are associated with ocular adverse drug reactions that are mainly inflammatory, i.e. conjunctivitis, uveitis and episcleritis [10]. Blurred vision can be associated with an inflammatory adverse drug reaction. Two studies were found where the use of bisphosphonates was associated with ...
... Bisphosphonates are associated with ocular adverse drug reactions that are mainly inflammatory, i.e. conjunctivitis, uveitis and episcleritis [10]. Blurred vision can be associated with an inflammatory adverse drug reaction. Two studies were found where the use of bisphosphonates was associated with ...