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Bacterial plasmids
Bacterial plasmids

... and usually carry genes that are useful but not essential to survival: e.g. genes which make bacteria resistant to antibiotics. Plasmids are released by dead bacteria and absorbed by those still living thus genetic information is exchanged (sexual reproduction?). ...
Exam #2 KEY
Exam #2 KEY

... Atlantic salmon. In the presence of Vikocyde, protein synthesis in E. coli initiates, but only dipeptides (two amino acids linked together) are formed, and these remain bound to the ribosomes. Vikocyde most likely inhibits protein synthesis by blocking: a. binding of formylmethionyl-tRNA b. transloc ...
Name: 1) Which statement best describes the relationship between
Name: 1) Which statement best describes the relationship between

... sequence of the subunits A, T, C, and G in the DNA of the organism  shape of the protein molecules in the organelles of the organism  type of amino acids in the cells of the organism  size of simple sugar molecules in the organs of the organism  ...
Secondary structures
Secondary structures

... Promoter: involved in transcription initiation (TF/RNApol-binding sites) TSS: transcription start site UTRs: un-translated regions (important for translational control) Exons will be spliced together by removal of the Introns Poly-adenylation site important for transcription termination (but also: m ...
DISTINCTION BETWEEN AOX PLANT
DISTINCTION BETWEEN AOX PLANT

... (but also: mRNA stability, export mRNA from nucleus etc.) ...
File
File

... i. The passing on of characteristics from parents to offspring b. Traits i. Characteristics that are inherited c. Gene i. A heritable factor that controls a specific characteristic ii. Estimated 30,000 genes which you have and are organized into chromosomes 1. One gene and one polypeptide – each pro ...
Mutations and Metabolic Pathways
Mutations and Metabolic Pathways

... Porphyrias are a group of rare disorders passed down through families, in which an important part of haemoglobin, called haem, is not made properly. Normally, the body makes haem in a multi-step process. Porphyrins are made during several steps of this process. Patients with porphyria have a deficie ...
What Molecular Has Taught Us About Blood Groups Old And New
What Molecular Has Taught Us About Blood Groups Old And New

... • Jra was first described in 1970 as a high frequency antigen • Anti-Jra has caused transfusion reactions but rarely HDFN • The Jr(a–) phenotype is found Asians (Japanese) – also in Northern Europe, Mexico, and Middle East ...
EOC Review Packet #2
EOC Review Packet #2

... • In humans there is a disease called Phenylketonuria (PKU)which is caused by a recessive allele. People with this allele have a defective enzyme and cannot break down the amino acid phenylalanine. This disease can result in mental retardation or death. Let “E” represent the normal enzyme. Also in h ...
CM - Overview of HL7V2 genetic report lite for LOINC Lab commitee
CM - Overview of HL7V2 genetic report lite for LOINC Lab commitee

... ATN1 gene allele 1.CAG repeats – reported as a number ...
Tool 1
Tool 1

... viruses from different groups, so often a positive PCR detection will in itself help to classify the viruses into broad groups. Following detection by PCR, further characterization (typing) of these viruses can be done by determination of the sequence (DNA letters) of the whole or parts of the viral ...
infographic
infographic

... Although all our cells need the same DNA to function, over time, they don't use it all. Throughout its life, and depending on specific conditions, each cell ‘expresses’, or switches on, only a selection of its genes. The rest are switched off. This process is known as gene regulation. ...
PCR
PCR

...  DNA concentration is estimated by measuring the absorbance at 260nm (A260), adjusting the A260 measurement for turbidity (A320 measurement), multiplying by the dilution factor, and using the relationship that A260 of 1.0= 50 µg/ml pure double stranded DNA.  DNA purity calculate as the ratio of th ...
Breeding - Farming Ahead
Breeding - Farming Ahead

... with three repeats such as ABABAB while another will have six repeats such as ABABABABABAB. The number of times the code is repeated varies between animals but a parent will pass its motif to the next generation in exactly the same form. By studying enough of the microsatellites on different chromos ...


... Piece of DNA that codes for a protein with a start and stop codon. 48. (1 pt.) Explain what it means to say that a gene is expressed. It means that the gene has gone through transcription and translation to make a protein 49. (2 pts.) Explain phenotypic plasticity. The ability of an organism with a ...
Metzenberg, R.L. and J. Grotelueschen
Metzenberg, R.L. and J. Grotelueschen

... remain unidentified and themselves to be anonymous until publication or five years have elapsed, whichever is first. Even without identification, the results enrich the map and help others map their clones to a chromosome. If you have found these data useful please pass on the favor by pencilling an ...
Gene Mutations
Gene Mutations

... for a C at nucleotide 1609 converted a glutamine codon (CAG) to a STOP codon (TAG). The protein produced by this patient had only the first 493 amino acids of the normal chain of 1480 and could not function. ...
Slides - Department of Computer Science
Slides - Department of Computer Science

... What is bioinformatics • National Institutes of Health (NIH): – Research, development, or application of computational tools and approaches for expanding the use of biological, medical, behavioral or health data, including those to acquire, store, organize, archive, analyze, or ...
Slide 1
Slide 1

... – If chromosome is gained (3 copies = trisomic) = individual may survive but only in a few cases and will be mentally impaired • Example: Trisopy 21 (Down syndrome) ...
BACTERIA TRANSFORMATION LAB (ACTIVITY)
BACTERIA TRANSFORMATION LAB (ACTIVITY)

... One of the ways that bacteria remain genetically diverse is through the naturally occurring processes of transformation. During transformation bacteria take up plasmid DNA from their environment. Plasmids are small, circular pieces DNA that can be exchanged naturally between bacteria. Plasmids may c ...
Introduction to Genetic - Home
Introduction to Genetic - Home

... Methods for detecting genetic abnormalities, depend upon the size and nature of the mutation. Some techniques are applied to test for chromosomal DNA itself, some to the RNA copies and some to the protein product of the gene ...
Chapter 7 Supplement
Chapter 7 Supplement

... molecule of recombinant DNA is inserted into a bacterial cell, the bacterium is able to produce the gene product, usually a protein. Thus, microorganisms (primarily bacteria) can be genetically engineered to produce substances (gene products) that they would not normally manufacture. Paul Berg won ...
CP Biology Chapter 8 Structure of DNA notes
CP Biology Chapter 8 Structure of DNA notes

3D structures of RNA
3D structures of RNA

... • mRNA can now be measured for all the genes in a cell at ones through microarray ...
Genes in Context Gene–Environment Interplay
Genes in Context Gene–Environment Interplay

... question: ‘‘If the effects of genetic variation can vary depending on characteristics of the environment, then what are environments doing to genes to alter their impact?’’ To address this question, we must first address the following question: ‘‘What do genes do?’’ Historically, gene was a term use ...
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Cell-free fetal DNA

Cell-free fetal DNA (cffDNA) is fetal DNA circulating freely in the maternal blood stream. It can be sampled by venipuncture on the mother. Analysis of cffDNA provides a method of non-invasive prenatal diagnosis.cffDNA originates from the trophoblasts making up the placenta. It is estimated that 2-6% of the DNA in the maternal blood is fetal in origin. The fetal DNA is fragmented and makes its way into the maternal bloodstream via shedding of the placental microparticles into the maternal bloodstream (figure 1). Studies have shown that cffDNA can first be observed as early as 7 weeks gestation, and the amount of cffDNA increases as the pregnancy progresses. cffDNA diminishes quickly after the birth of the baby, so that it is no longer detectable in the maternal blood approximately 2 hours after birth. cffDNA is significantly smaller than the maternal DNA in the bloodstream, with fragments approximately 200bp in size. Many protocols to extract the fetal DNA from the maternal plasma use its size to distinguish it from the maternal DNA.Studies have looked at, and some even optimized, protocols for testing non-compatible RhD factors, sex determination for X-linked genetic disorders and testing for single gene disorders. Current studies are now looking at determining aneuploidies in the developing fetus. These protocols can be done earlier than the current prenatal testing methods, and have no risk of spontaneous abortion, unlike current prenatal testing methods. Non-invasive prenatal diagnosis (NIPD) has been implemented in the UK and parts of the US; it has clear benefits above the standard tests of chorionic villi sample (CVS) and amniocentesis which have procedure-related miscarriage risks of about 1 in 100 pregnancies and 1 in 200 pregnancies, respectively.As a method of prenatal diagnosis, cell-free fetal DNA techniques share the same ethical and practical issues, such as the possibility of prenatal sex discernment and sex selection.
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