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Genetics - SCHOOLinSITES
Genetics - SCHOOLinSITES

Introduction to Molecular Biology
Introduction to Molecular Biology

... followed later and in 1952 Watson and Crick disclosed the double helix structure of DNA. All living organisms have common characteristics such as replication, nutrition, growing and interaction with their environment. An organism is composed of organs which perform specific functions. Organs are mad ...
MGG330 L1-2007
MGG330 L1-2007

... Similar to gene expression array Differs in that all exons are covered in probe sets ...
SexLinked
SexLinked

... located on the sex chromosomes, usually the X chromosome. These traits are called SEX-LINKED TRAITS. This activity will help you understand how human sex-linked traits are passed from one generation to the next. Hemophilia is a recessive disorder caused by a mutation on the X chromosome. The dominan ...
Fruit flies and Alzheimer`s disease
Fruit flies and Alzheimer`s disease

... Alcaptonuria The first genetic disease to be described, called alcaptonuria, was discovered by Archibald Garrod in 1908. Patients with this disease suffer with arthritis (pain and damage to joints) and Garrod noticed that their urine turned black when exposed to the air. The arthritis and the colour ...
“Ancient” Viruses
“Ancient” Viruses

... protein-primed process that occurs in the nucleus: 1. A preterminal protein (pTP)/DNA polymerase (Pol) complex binds to the 3’ origin of replication using both E2 proteins. 2 dCTP is recruited to form a phosphodiester bond with the pTP serine. 3. Continuous 5’ to 3’ synthesis of DNA by viral polymer ...
CST Review
CST Review

... 45. The gene for color vision (C) is dominant to the gene for color blindness (c) and is located on the X chromosome. If a color blind man and a woman with homozygous normal color vision have children, what are the chances that they will have a colorblind child? 46. Why do some lethal (deadly) allel ...
In Silico Mapping of Complex Disease
In Silico Mapping of Complex Disease

... I will refer you to the notes from Weeks 3 and 4 of my Stat 260, Spring 1998. There I describe mouse crosses and and linkage ...
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... For synthesis of protein, a succession of tRNA molecules charged with appropriate amino acids are brought together with an mRNA molecule and matched up by base-pairing through their anti-codons. The amino acids are linked together to extend the growing protein chain, and the tRNAs are released. This ...
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DNA’s Discovery and Structure

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... and A whenever it encounters the six-base sequence AAGCTT. 4. Examine the DNA sequence for the plasmid and the jellyfish gene. Which restriction enzyme should you use to cut the plasmid? The jellyfish gene? Remember, when you cut each gene, you need to retain the start and stop sequences. Should you ...
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Section 3 Vocabulary Vocabulary Term Definition heritable

... are uninterrupted segments of DNA which carry specific instructions for specific characteristics for an organism ...
DNA Replication - :: FAPERTA UGM
DNA Replication - :: FAPERTA UGM

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6.1 Mutation

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Chap2 DNA RNA and Protein

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INBREEDING Definition

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... One allele masked another, one allele was dominant over the other in the F1 generation. • 2. Principle of Segregation: When gametes are formed, the pairs of hereditary factors (genes) become separated, so that each sex cell (egg/sperm) receives only one kind of gene. ...
Chapter 2 DNA, RNA, Transcription and Translation I. DNA
Chapter 2 DNA, RNA, Transcription and Translation I. DNA

... Effector (or called inducer) molecules bind to the repressor and release from the operator region on (induction). e.g. the lacZ gene is off w/o -galactoside, when the substrate is added, the enzyme activity appears within 2-3 min IPTG (isopropyl-beta-Dthiogalactopyranoside), a synthetic analogue ...
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CST Review Study Guide Biochemistry (Unit 2) 1. What elements

... 34. The gene for color vision (C) is dominant to the gene for color blindness (c) and is located on the X chromosome. If a color blind man and a woman with homozygous normal color vision have children, what are the chances that they will have a colorblind child? 35. Why do some lethal (deadly) allel ...
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... Figure 22.3 The genes of the retrovirus are expressed as polyproteins that are processed into individual products. ...
RECOMBINANT DNA
RECOMBINANT DNA

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Unit 3 take home exam
Unit 3 take home exam

... D. recessive 16. Which of the following is true about X-linked disorders? A. most are dominant B. most are females C. daughters of an X-linked disorder father are often carriers D. daughters of a carrier are likely to have the condition 17. Down syndrome is seen in a person with: A. XXX B. XXY C. XO ...
Genomics for the Rancher: How Does it Work and What
Genomics for the Rancher: How Does it Work and What

... Mendel's Laws of Inheritance which are key components of modern genetic predictions today. Deoxyribonucleic acid or DNA was first isolated by the Swiss physician Friedrich Miescher who, in 1869, discovered a microscopic substance in the pus of discarded surgical bandages that later was characterized ...
Lesson 7: Genetic Disorders & Gene Therapy
Lesson 7: Genetic Disorders & Gene Therapy

... breast cancer, fragile X syndrome, Huntington disease, Duchenne muscular dystrophy • Tests are up to 99% accurate • Tests can be run on embryos created by in-vitro fertilization prior to implantation ...
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Cell-free fetal DNA

Cell-free fetal DNA (cffDNA) is fetal DNA circulating freely in the maternal blood stream. It can be sampled by venipuncture on the mother. Analysis of cffDNA provides a method of non-invasive prenatal diagnosis.cffDNA originates from the trophoblasts making up the placenta. It is estimated that 2-6% of the DNA in the maternal blood is fetal in origin. The fetal DNA is fragmented and makes its way into the maternal bloodstream via shedding of the placental microparticles into the maternal bloodstream (figure 1). Studies have shown that cffDNA can first be observed as early as 7 weeks gestation, and the amount of cffDNA increases as the pregnancy progresses. cffDNA diminishes quickly after the birth of the baby, so that it is no longer detectable in the maternal blood approximately 2 hours after birth. cffDNA is significantly smaller than the maternal DNA in the bloodstream, with fragments approximately 200bp in size. Many protocols to extract the fetal DNA from the maternal plasma use its size to distinguish it from the maternal DNA.Studies have looked at, and some even optimized, protocols for testing non-compatible RhD factors, sex determination for X-linked genetic disorders and testing for single gene disorders. Current studies are now looking at determining aneuploidies in the developing fetus. These protocols can be done earlier than the current prenatal testing methods, and have no risk of spontaneous abortion, unlike current prenatal testing methods. Non-invasive prenatal diagnosis (NIPD) has been implemented in the UK and parts of the US; it has clear benefits above the standard tests of chorionic villi sample (CVS) and amniocentesis which have procedure-related miscarriage risks of about 1 in 100 pregnancies and 1 in 200 pregnancies, respectively.As a method of prenatal diagnosis, cell-free fetal DNA techniques share the same ethical and practical issues, such as the possibility of prenatal sex discernment and sex selection.
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