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Transposable Elements
Transposable Elements

... function, and produce a white kernel. When the element moves, the pigment gene function is restored, producing a reddish splotch of color on the skin of the kernel. ...
Chapter 2 PowerPoint Slides
Chapter 2 PowerPoint Slides

... • provides the "score" (or "cost") of aligning one amino acid to another ...
Red line Introduction
Red line Introduction

... Genomes are complex and dynamic (queer). DNA sequence is information. DNA sequence is biological identity. Gene annotation adds meaning to DNA sequence. Concept of gene continues to evolve. A genome is more than genes. ...
Genética Molecular em Medicina Transfusional
Genética Molecular em Medicina Transfusional

... • Quick, highly redundant – requires 7-9X coverage for sequencing reads of 500-750bp. This means that for the Human Genome of 3 billion bp, 21-27 billion bases need to be sequence to provide adequate fragment overlap. • Computationally intensive • Troubles with repetitive DNA • Original strategy of ...


... Biology Professor Awarded Grant to Purchase Ion Proton DNA Sequencer for ECU GREENVILLE, N.C. (April 10, 2014) — Dr. Edmund Stellwag, director of the East Carolina University Genomics Core Facility and Biotechnology Education Program and associate professor of biology, has received a North Carolina ...
Human Genome Project and Sequencing
Human Genome Project and Sequencing

NYU_Lec1 - NDSU Computer Science
NYU_Lec1 - NDSU Computer Science

... • Provide software (site licenses), computing hardware, and databases • Train scientists to use the software ...
Red Line - iPlant Pods
Red Line - iPlant Pods

... Genomes are complex and dynamic (queer). DNA sequence is information. DNA sequence is biological identity. Gene annotation adds meaning to DNA sequence. Concept of gene continues to evolve. A genome is more than genes. ...
DNA, Genes and Chromosomes
DNA, Genes and Chromosomes

... 2. To obtain a merit you need to use pictures of your DNA model in a flow diagram showing the progression from a cell to a gene writing descriptions. 3. A distinction will be achieved if you produce a poster writing a summary about how genes can be shuffled ...
Whole genome shotgun sequencing
Whole genome shotgun sequencing

... (b) Sequence of mutant allele Hybridize each oligo (separately) to Southern blot of DNA. Use conditions that allow only oligonucleotides that are 100% complementary to DNA on blot to hybridize. If only normal oligo hybridizes---homozygous normal allele If only mutant oligo hybridizes --- homozygous ...
BIOL 433 Plant Genetics Term 1, 2005
BIOL 433 Plant Genetics Term 1, 2005

... Sequence the BACs in the minimum tiling path. Contigs can be linked by identifying a clone that spans two contigs. ...
BIOL 433 Plant Genetics Term 1, 2005
BIOL 433 Plant Genetics Term 1, 2005

... Sequence the BACs in the minimum tiling path. Contigs can be linked by identifying a clone that spans two contigs. ...
The World of Microbes on the Internet
The World of Microbes on the Internet

... Director of the National Human Genome Research Institute N Engl J Med 1999 882:42-65 ...
Epigenetics
Epigenetics

... ways, both which may turn genes off or on. • The first type of mark, called DNA methylation, directly affects the DNA in your genome. This can also occur with acetylation. • In this process, chemical tags called methyl groups attach to the backbone of the DNA molecule in specific places. • The methy ...
GENOME SEQUENCING AND OBJECTIVES
GENOME SEQUENCING AND OBJECTIVES

Quiz 3-DNA.doc
Quiz 3-DNA.doc

... 7. How many amino acids are there? a. 20 b. 30 c. 40 d. 10 8. The disease that stops someone’s hemoglobin from getting to part of their body is called: a. Sickle-cell anemia b. Platelet dialysis c. Hemoglobina pseudomona d. Alzheimers 9. Only ___% of genes produce protein a. 1 b. 10 c. 20 d. 30 e. 4 ...
Study Questions – Chapter 1
Study Questions – Chapter 1

... 1. Genome-wide associations have been hailed for providing breakthroughs in our understanding of the underlying basis of complex genetic traits, but they can be a real challenge to carry out. What are some of the factors that can make a difference in how successful such studies are? As you consider ...
Leq: what is cloning and how is it done?
Leq: what is cloning and how is it done?

... genomes of various organisms, but the knowledge of full genomes has created the possibility for the field of functional genomics, mainly concerned with patterns of gene expression during various conditions. http://www.news-medical.net/health/What-isGenomics.aspx ...
Biotechnology Key Terms and Concepts
Biotechnology Key Terms and Concepts

... analyzing and manipulating genomes of organisms at the molecular level (DNA technology) C. Genome-complete set of an organism’s genetic material D. Human genome project– a project aimed at sequencing the human genome and identifying its genes E. Recombinant DNA technologytechnology that combines gen ...
Finding needles in a haystack - predicting gene regulatory pathways
Finding needles in a haystack - predicting gene regulatory pathways

... experimentally and there are considerable efforts underway to expedite the determination of many of the protein folds and structures resulting from these results. However, the regulatory networks which underpin the normal functioning of cells and which represent the interactions between the genome p ...
Protocol S1
Protocol S1

... SNP analysis. SNPs among the three SS2 genomes were detected by BLSTNB (e<10-5). Synonymous and nonsynonymous sites were determined by ClustalW[2]. The software of YN00[10] combined with PAML package [11] was utilized for Ka and Ks calculations, resulting in all the relevant numerical values. Predic ...
Certificate of Analysis MicroSeq(R) 500 16S rDNA
Certificate of Analysis MicroSeq(R) 500 16S rDNA

... The combined forward and reverse sequencing accuracy is at least 99.5 % for the amplified product from E. coli genomic DNA. The combined forward and reverse sequencing clear read is at least 476 base pairs for the fragment sequenced using the amplified PCR product from E. coli genomic DNA ...
Introduction to Next-Generation Sequence analysis
Introduction to Next-Generation Sequence analysis

... • The term genome was used by German botanist Hans Winker in 1920 • Collection of genes in haploid set of chromosomes • Now it encompasses all DNA in a cell • In 1986 mouse geneticist Thomas Roderick used Genomics for “mapping, sequencing and characterizing genomes” ...
Functional Genomics
Functional Genomics

... to the Study of Eukaryotes ...
Chapter 9: Gene Transfer, Genetic Engineering, and Genomics
Chapter 9: Gene Transfer, Genetic Engineering, and Genomics

... This chapter describes how prokaryotes can acquire genes from the environment and take on new characteristics, a process that no other living creature can perform. It follows the method prokaryotes use to exchange genes and discusses how viruses can carry genes between bacterial cells. The section o ...
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Genomics

Genomics is a discipline in genetics that applies recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyze the function and structure of genomes (the complete set of DNA within a single cell of an organism). Advances in genomics have triggered a revolution in discovery-based research to understand even the most complex biological systems such as the brain. The field includes efforts to determine the entire DNA sequence of organisms and fine-scale genetic mapping. The field also includes studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the definition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome's networks.
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