Introduction to self-assembly Self
... sequence space for 24-nt RNAs (Jiménez et al., 2014). Longer RNAs capable of extending a dsRNA overhang up to their own length have been evolved through directed evolution (see e.g. Attwater et al., 2013) and can function under imperfect conditions such as within ice. Important functions such as pr ...
... sequence space for 24-nt RNAs (Jiménez et al., 2014). Longer RNAs capable of extending a dsRNA overhang up to their own length have been evolved through directed evolution (see e.g. Attwater et al., 2013) and can function under imperfect conditions such as within ice. Important functions such as pr ...
All Alus are approximately 300 bp in length and derive
... single recognition site for the restriction enzyme AluI located near the middle of the Alu element. Human chromosomes contain about 1,000,000 Alu copies, which equal 10% of the total genome. Alu elements probably arose from a gene that codes for RNA signal peptide for export ...
... single recognition site for the restriction enzyme AluI located near the middle of the Alu element. Human chromosomes contain about 1,000,000 Alu copies, which equal 10% of the total genome. Alu elements probably arose from a gene that codes for RNA signal peptide for export ...
Gene Regulation
... • Although the chromatin modifications just discussed do not alter DNA sequence, they may be passed to future generations of cells. • The inheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence is called epigenetic inheritance. ...
... • Although the chromatin modifications just discussed do not alter DNA sequence, they may be passed to future generations of cells. • The inheritance of traits transmitted by mechanisms not directly involving the nucleotide sequence is called epigenetic inheritance. ...
Differentially Expressed Genes in Blood from Young Pigs between
... and technical variables (processing batches, RNA concentration before globin depletion, RNA integrity number (RIN) after globin depletion). With this model, we found 453 DEGs (FDR ≤ 0.05) between the two lines, with 50 DEGs having fold change ≥ 2. Functional terms including small molecule biosynthet ...
... and technical variables (processing batches, RNA concentration before globin depletion, RNA integrity number (RIN) after globin depletion). With this model, we found 453 DEGs (FDR ≤ 0.05) between the two lines, with 50 DEGs having fold change ≥ 2. Functional terms including small molecule biosynthet ...
Gene Transcription in Prokaryotes
... • Single DNA-binding protein may act as either a repressor or an activator – araC protein ...
... • Single DNA-binding protein may act as either a repressor or an activator – araC protein ...
RNA Processing in Eukaryotes
... Other genes in the mitochondrial genome encode 40- to 80-nucleotide guide RNAs. One or more of these molecules interacts by complementary base pairing with some of the nucleotides in the pre-mRNA transcript. However, the guide RNA has more A nucleotides than the pre-mRNA has U nucleotides to bind wi ...
... Other genes in the mitochondrial genome encode 40- to 80-nucleotide guide RNAs. One or more of these molecules interacts by complementary base pairing with some of the nucleotides in the pre-mRNA transcript. However, the guide RNA has more A nucleotides than the pre-mRNA has U nucleotides to bind wi ...
Transcription
... Transcription and genome integrity affect each other, e.g. DNA lesions inhibit progress of the polymerase -> repair TFIIH participates in both ...
... Transcription and genome integrity affect each other, e.g. DNA lesions inhibit progress of the polymerase -> repair TFIIH participates in both ...
William Yin
... RNA interference (RNAi) is a highly potent and specific process where the presence of certain fragments of double-stranded RNA interferes with the expression of a particular gene which shares a homologous sequence with the dsRNA. The RNA interference machinery cuts up double-stranded RNA molecule wi ...
... RNA interference (RNAi) is a highly potent and specific process where the presence of certain fragments of double-stranded RNA interferes with the expression of a particular gene which shares a homologous sequence with the dsRNA. The RNA interference machinery cuts up double-stranded RNA molecule wi ...
Gene regulation and bacteriophage
... the host, clearing the area. Another important protein is encoded by cro, standing for control of repressor and other genes. The cI repressor blocks the expression of most lambda genes except itself, and Cro blocks the expression of cI. The workings of the switch are illustrated in Figure 5. The gen ...
... the host, clearing the area. Another important protein is encoded by cro, standing for control of repressor and other genes. The cI repressor blocks the expression of most lambda genes except itself, and Cro blocks the expression of cI. The workings of the switch are illustrated in Figure 5. The gen ...
Chapter 5
... copies of nonfunctional transposons. • There are many duplications of large chromosome regions. ...
... copies of nonfunctional transposons. • There are many duplications of large chromosome regions. ...
First week lectures
... In contrast to RNA no complex three dimensional fold or enzymatic function (only hard disk no CPU). A double helix (A/B/Z) of complementing base pairs, very useful in information processing and corrections ...
... In contrast to RNA no complex three dimensional fold or enzymatic function (only hard disk no CPU). A double helix (A/B/Z) of complementing base pairs, very useful in information processing and corrections ...
The Copernican revolution of the biology
... Iris Jonkers & John T. Nature Reviews Genetics 16, 2015; Lis, Lanctôt et al. Nature Reviews Genetics 8, 2007 ...
... Iris Jonkers & John T. Nature Reviews Genetics 16, 2015; Lis, Lanctôt et al. Nature Reviews Genetics 8, 2007 ...
U6 snRNA genes of Arabidopsis are transcribed
... initiation by pol II are generally situated upstream of the coding region. On the other hand, the promoters of pol HI genes are usually located internally, within the coding region; tRNA and 5S rRNA genes containing internal A and B (or C) boxes are examples of such genes (2,5,6). In recent years, h ...
... initiation by pol II are generally situated upstream of the coding region. On the other hand, the promoters of pol HI genes are usually located internally, within the coding region; tRNA and 5S rRNA genes containing internal A and B (or C) boxes are examples of such genes (2,5,6). In recent years, h ...
Ovation™ RNA Amplification System
... Ovation™ RNA Amplification System A Comparison of Gene Expression Levels in Non-Amplified and Amplified RNA ...
... Ovation™ RNA Amplification System A Comparison of Gene Expression Levels in Non-Amplified and Amplified RNA ...
text s9: yellow/major royal jelly protein family
... as they are part of the Y-c clade). Finally, the MRJP subfamiliy is restricted to Hymenoptera, and characterized by independent expansions in all three represented taxa, as all are more closely related to their intraspecific paralogues than to genes in other taxa. Although only three complete MRJP g ...
... as they are part of the Y-c clade). Finally, the MRJP subfamiliy is restricted to Hymenoptera, and characterized by independent expansions in all three represented taxa, as all are more closely related to their intraspecific paralogues than to genes in other taxa. Although only three complete MRJP g ...
The best-studied nuclear compartments are the
... in mammalian interphase nuclei. Artificial tandemly repeated U2 snRNA genes were associated with CBs, and that their association was dependent on the transcription activity of those genes. Furthermore, when U2 expression levels were increased by increasing the U2 copy number, their association with ...
... in mammalian interphase nuclei. Artificial tandemly repeated U2 snRNA genes were associated with CBs, and that their association was dependent on the transcription activity of those genes. Furthermore, when U2 expression levels were increased by increasing the U2 copy number, their association with ...
Evolution of Development (EvoDevo) •Development is the process
... What animals have these genes? How do the genes look different? How do the animals look different (morphology and complexity)? ...
... What animals have these genes? How do the genes look different? How do the animals look different (morphology and complexity)? ...
first of Chapter 11: Gene Regulation
... lac operon model • 2 kinds of genes: structural, regulatory elements. • Polycistronic structural genes, with promoter and operator constitute the lac operon. • Promoter mutants make no lac mRNA. • lacI gene makes a repressor, which binds to the operator. • When operator is ‘repressed’ no transcript ...
... lac operon model • 2 kinds of genes: structural, regulatory elements. • Polycistronic structural genes, with promoter and operator constitute the lac operon. • Promoter mutants make no lac mRNA. • lacI gene makes a repressor, which binds to the operator. • When operator is ‘repressed’ no transcript ...
Gene Section DHX9 (DEAH (Asp Glu Ala
... DHX9 is a nucleic-acid helicase that unwinds doublestranded DNA and RNA in a nucleotide dependent manner. It acts as a transcriptional coactivator which stimulates transcription by interacting with the transcriptional coactivator CBP/p300, the breast cancer protein BRCA1, the RNA polymerase II and h ...
... DHX9 is a nucleic-acid helicase that unwinds doublestranded DNA and RNA in a nucleotide dependent manner. It acts as a transcriptional coactivator which stimulates transcription by interacting with the transcriptional coactivator CBP/p300, the breast cancer protein BRCA1, the RNA polymerase II and h ...
Leukaemia Section t(X;11)(q21;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology
... Dual-color interphase FISH analysis of the 11q23 and Xq21 breakpoints with BAC clones. (A) FISH analysis with 11q23 specific BACs: RP11-468P24 (red signals) and RP11-206G12 (green signals). Three red signals indicate translocation within the genomic region represented by RP11-468P24. (B) FISH analys ...
... Dual-color interphase FISH analysis of the 11q23 and Xq21 breakpoints with BAC clones. (A) FISH analysis with 11q23 specific BACs: RP11-468P24 (red signals) and RP11-206G12 (green signals). Three red signals indicate translocation within the genomic region represented by RP11-468P24. (B) FISH analys ...
Spotted
... Classification according to GO (Gene Ontology) - Gene Ontology is a “controlled vocabulary that can be applied to all eukaryotes “. Each gene product is classified in one or more categories. - Is distribution of missexpressed genes significantly different from the one of our initial set of genes? - ...
... Classification according to GO (Gene Ontology) - Gene Ontology is a “controlled vocabulary that can be applied to all eukaryotes “. Each gene product is classified in one or more categories. - Is distribution of missexpressed genes significantly different from the one of our initial set of genes? - ...
Analysis of ATP Synthase Genes within Elizabethkingia anophelis R26
... transcribed gene 154 and gene 159, with a fold change of 2.0 and 1.5, to achieve this. So, in cefotax, gene 156 and gene 157 were not needed in producing ATP for energy, so transcription decreased, creating a fold change of 1.0 and 1.3. While living in imipenem, the cell needed to make ATP for energ ...
... transcribed gene 154 and gene 159, with a fold change of 2.0 and 1.5, to achieve this. So, in cefotax, gene 156 and gene 157 were not needed in producing ATP for energy, so transcription decreased, creating a fold change of 1.0 and 1.3. While living in imipenem, the cell needed to make ATP for energ ...
The Human Genome Project
... • By selecting different pieces of a gene, your body can make many kinds of proteins. (This process is called alternative splicing.) • If a gene is “expressed” that means it is turned on and it will make proteins. ...
... • By selecting different pieces of a gene, your body can make many kinds of proteins. (This process is called alternative splicing.) • If a gene is “expressed” that means it is turned on and it will make proteins. ...
Transposons - iPlant Pods
... (1) At the beginning of kernel development, the Ds transposon inserts into the colored (C) gene, resulting in colorless tissue. (2) Ds transposition early in kernel development restores the C gene, giving rise to a large colored sector. (3) Transposition later in kernel development results in smalle ...
... (1) At the beginning of kernel development, the Ds transposon inserts into the colored (C) gene, resulting in colorless tissue. (2) Ds transposition early in kernel development restores the C gene, giving rise to a large colored sector. (3) Transposition later in kernel development results in smalle ...