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Rallying the troops of the immune system to fight cancer
Rallying the troops of the immune system to fight cancer

... STING is activated by intracellular signals, specifically cyclic dinucleotides, which are produced when double stranded DNA is detected in the wrong place, a hallmark of viral infection. Aduro has altered cyclic dinucleotides to make them more potent and stable than the natural versions, creating dr ...
Controlled experiment
Controlled experiment

... Thyroid gland- The function of the thyroid gland is to take iodine, found in many foods, and convert it into thyroid hormones: thyroxine (T4) and triiodothyronine (T3). Every cell in the body depends upon thyroid hormones for regu ...
Living Environment Immune System and Disease Aim What are the
Living Environment Immune System and Disease Aim What are the

... Phagocyte: Cells that engulf foreign cells/material Humoral Immunity Immunity against pathogens in body fluids by white blood cells(B+T) B lymphocyte(B-cell): Produces antibodies, have memory T lymphocyte(T-cell): Activate B-Cells Antibody: a protein that helps destroy pathogens Cell Mediated Immuni ...
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a5_1_1-1_done

Table 2A. Summary of Genetics Activities Activity 1: Mitosis and
Table 2A. Summary of Genetics Activities Activity 1: Mitosis and

LINEs
LINEs

... Non-autonomous (successful freeloaders! ‘borrow’ RT from other sources such as LINEs)  ~100-300bp long  Internal polymerase III promoter  No proteins  Share 3’ ends with LINEs  3 related SINE families in humans – active Alu, inactive MIR and Ther2/MIR3. ...
Genetics - Mobile County Public Schools
Genetics - Mobile County Public Schools

... Explain the structure of eukaryotic chromosomes, including transposons, introns, and exons. Compare spermatogenesis and oogenesis using charts. Describe occurrences and effects of sex linkage, autosomal linkage, crossover, multiple alleles, and polygenes Describe the structure and function of DNA, i ...
Holly gets sick
Holly gets sick

... particle made up of genetic material and protein that can invade living cells. ...
Chapter 17 Adaptive Immunity
Chapter 17 Adaptive Immunity

sCD100 Human Chinese Hamster Ovary Cells (CHO)
sCD100 Human Chinese Hamster Ovary Cells (CHO)

... Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). ...
Document
Document

... modifications of the histones loosen DNA binding ...
DNA Technology Notes
DNA Technology Notes

... Scientists use several techniques to manipulate DNA (cloning = copying genes, transferring genes between organisms, etc.) DNA must first be extracted and precisely cut so that it can be studied. Restriction enzymes (or molecular scissors) cut DNA at a certain nucleotide sequence called a restriction ...
Lecture 6 S - BEHESHTI MAAL
Lecture 6 S - BEHESHTI MAAL

... – 3- during phage reassembly, bacterial DNA incorporated in capsid of bacteriophage ...
Malaria - Emi Leonard
Malaria - Emi Leonard

... Malarial DNA Binds TLR9 and HZ Traffics DNA into a TLR9-Positive Compartment • DOTAP- reagent that targets nucleotides into endosomal compartment • malaria DNA + DOTAP strongly activated cells to secrete cytokines • HZ/DOTAP didn't activate FL-DCs in TLR9-/- mouse cells* • malaria DNA + HZ is as po ...
1 - Welcome to people.pharmacy.purdue.edu!
1 - Welcome to people.pharmacy.purdue.edu!

... d. the virus can infect and proliferate in human cells to some extent, but is not very pathogenic. e. the virus has been generated by genetic engineering to contain genes coding for the surface proteins of a totally separate viral strain. 20. (3 points) The use of killed or inactivated viruses as va ...
BAC vectors (Bacterial Artificial Chromosome)
BAC vectors (Bacterial Artificial Chromosome)

... capable of replicating and forming plagues on E. coli host cells. To prepare infectious λ virions carrying recombinant DNA, the phage assembly process is carried out in vitro. In one method, E. coli cells are infected with a mutant λ defective in A proteins, one of the two proteins required for pack ...
BIO.6
BIO.6

... homologous chromosome. Now the sister chromatids are not necessarily identical, leading to four entirely different gametes if there is only one chromosome, and sixteen different possible gametes if there are two pairs of homologous chromosomes. In humans with 23 homologous pairs of chromosomes and w ...
2017 DNA Lab Programmes Booklet
2017 DNA Lab Programmes Booklet

... PTC/ Genetic Engineering ...
Quizzes
Quizzes

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Manipulation DNA
Manipulation DNA

... Some of the tools of biotechnology are natural components of cells. Restriction enzymes are made by bacteria to protect themselves from viruses. They inactivate the viral DNA by cutting it in specific places. DNA ligase is an enzyme that exist in all cells and is responsible for joining together str ...
Arianna Marini (PPT - 4345KB) - University of Birmingham Intranet
Arianna Marini (PPT - 4345KB) - University of Birmingham Intranet

... detoxified endotoxin, over-expression of protective antigens, and over-blebbing. • GMMA from this mutated strain are promising as an affordable vaccine against all N. meningitidis serogroups causing meningococcal disease in sub- Saharan Africa. • Evalution of fine-specificity of protection and mecha ...
B cells
B cells

... Certain genes are turned on in developing cells  Synthesizes proteins to be incorporated onto the PM called antigen receptors which bind specific antigens  All receptors on a single cell are identical ...
Access Slides
Access Slides

... • Conformational change: induce twisting and/or bending of DNA. ...
Visualizing gene expression and function at the cellular level
Visualizing gene expression and function at the cellular level

... After a wonderful week in Cell Biology laboratories, I would like to thank Professor Didier Picard and Kamilla Malinowska for all assistance and help, but also for all the time spent with me stirring up my interest. In addition, I would like to thank “La Science appelle les jeunes” for giving me the ...
Immunology – Immune System Overview
Immunology – Immune System Overview

... mechanisms whereby non-body particles are killed off or prevented from entering the body’s normal metabolism. There are a number of different pathogenic organisms which cause disease and thus disturb the body’s normal function. These are as follows:  Fungi  Bacteria  Parasites  Protozoa  Helmin ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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