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THE BODY`S DEFENSES
THE BODY`S DEFENSES

DNA Replication and DNA Repair Study Guide Focus on the
DNA Replication and DNA Repair Study Guide Focus on the

... b. ATP necessary for replication and repair!!!! 8. Mechanism of Replisome a. Helicase separates into leading and lagging strands i. SSBS maintain stability of single strands ii. Primase lays down RNA primers for DNA polymerase III iii. DNA polymerase III lays down nucleotides for leading and lagging ...
triplex-forming oligonucleotide (TFO)
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... genetic condition in which the γglobin genes continue to be expressed at very high levels in the adult life of individuals. • single base mutations or a small deletion in the 5′ flanking region of the γ-globin gene ...
BIOL 5870 - East Carolina University
BIOL 5870 - East Carolina University

... - from the examination of basic mechanisms that regulate gene expression in bacterial and eukaryotic systems, to a description of how regulation of gene expression lies at the heart of the process of development. Recent findings from sequencing whole genomes of several animals have revealed that the ...
CHAPTER 19 Natural Defenses Against Disease
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... • developing T cells are tested in the thymus – must recognize self MHC molecules • or fail to develop (anergy) – must not bind to both self MHC & any of the body’s own antigens • or die (clonal deletion - apoptosis) ...
The Adaptive Immune Response B
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... Most circulating IgG antibodies have half-lives of about 3 weeks. Some antibody-secreting plasma cells migrate to the bone marrow and live for years, continuing to produce low levels of antibodies. The majority of effector lymphocytes induced by an infectious pathogen die by apoptosis after the mic ...
TOLERANCE
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... Tolerance or immunity can also be influenced by the tissue microenvironment Immuno-suppressive mediators are secreted by the foetus and ...
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... Fetal development – red bone marrow releases lymphocytes Most become t cells, remainder become b cells  B and t cells stay in lymphatic organs. ...
Plant Biotechnology and GMOs
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... instead obtain aromatic amino acids from their diet. • Glyphosate has also been shown to inhibit other plant enzymes •Also has been found to affect animal enzymes. •The United States Environmental Protection Agency considers glyphosate to be relatively low in toxicity, and without carcinogenic or te ...
Old and new vaccine approaches
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... cell epitopes and the MHC restriction of the T cell response. Since the cellular immune response in humans is restricted to specific HLAs, any single epitope-based vaccine will probably not be effective in a broad range population. This can be overcome by the use of vaccines comprising several pepti ...
Chapter 13 Genetics and Biotechnology
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... replication, DNA ligase, joins the two DNA fragments chemically. Ligase joins DNA fragments that have sticky ends as well as those that have blunt ends. The resulting circular DNA molecule contains the plasmid DNA and the DNA fragment isolated from another genome. This recombinant plasmid DNA molecu ...
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... often rely on time-consuming growth in culture media, followed by isolation, biochemical identification, and sometimes serology Recent advances in technology make detection and identification faster, more convenient, more sensitive, and more specific than conventional assays ...
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Leukaemia Section t(10;11)(q22;q23) Atlas of Genetics and Cytogenetics in Oncology and Haematology
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... CXXC6 (CXXC finger 6) is also called LCX (leukemia-associated protein with a CXXC domain) or TET1. DNA/RNA 8497 bp representing the whole coding sequence. At least 12 exons. Contains 3 bipartite nuclear localization sites, 1 alpha helice coiled-coil region and 1 cysteine rich domain with high level ...
DNA Packaging - Semantic Scholar
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... both to catalyze and chaperone the assembly process. The scaffolding protein can be found inside the procapsid. Positioned at one of the twelve icosahedral vertices is a dodecameric complex of the virusencoded portal protein. This dodecameric complex, known as the portal or connector complex, forms ...
Protein Synthesis Worksheet
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... 15. (tRNA / mRNA) brings amino acids to the ribosome. 16. tRNA is found in the (nucleus / cytoplasm). 17. (Translation / Transcription) converts mRNA into a protein. 18. Translation takes place in the (cytoplasm / nucleus). 19. (one / three) codons equals one amino acid. 20. (amino acids / nucleotid ...
Wk5- Intracell Sig
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... Inhibition of adaptive immunity • Man-LAM binds the C-type lectin DCSIGN: – inhibits dendritic cell maturation and T-cell activation. – induces secretion of IL-10 to inhibit activated dendritic cells (adaptive immune response) and macrophages (innate immune response), as well as inhibiting producti ...
Hamel, Misse et al, J Virol 2015
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... Cell surface receptors Innate and adaptive responses Fetal CNS injury ...
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... • You can change the way an organism looks or behaves! • This process of taking DNA from one organism and putting into another is called transformation. ...
Preventing Communicable Diseases
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... Vaccines to Aid the Four Types of VaccinesBody’s Defenses 1. Live-virus vaccines are made to lose most of their diseasecausing properties while stimulating the production of antibodies. 2. Killed-virus vaccines use inactivated pathogens. The organism stimulates an immune response and antibodies are ...
Megan Silas - University of Illinois at Chicago
Megan Silas - University of Illinois at Chicago

... CAIR will disappear as it is converted into NCAIR by PurE Measure change in absorbance due to disappearance of CAIR Compare rate of reaction catalyzed by WT PurE versus H70N and truncated PurE Meyer, E., N.J. Leonard, B. Bhat, J. Stubbe, and J.M. Smith. "Purification and characterization of the purE ...
discov5_lecppt_Ch16
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... • Scientists have been able to track gene expression using a light-producing protein known as green fluorescent protein (GFP), which is extracted from jellyfish • New genes can be introduced into a cell in many different ways: – Plasmids – Viruses – Gene guns ...
Chapter22 - Extras Springer
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... Figure 22.5: Insertion of the F1-ATPase gene into a plasmid. The gene encoding the motor is flanked by two restriction enzyme sites, BamHI and PstI. The plasmid pQE-30 contains a number of restriction sites, including BamHI and PstI and a gene encoding for ampicillin resistance (Ampicillin is a pot ...
Immunization www.AssignmentPoint.com Immunization, or
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... orchestrate an immune response, and it will also develop the ability to quickly respond to a subsequent encounter because of immunological memory. This is a function of the adaptive immune system. Therefore, by exposing an animal to an immunogen in a controlled way, its body can learn to protect its ...
Leukaemia Section t(11;20)(q23;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(11;20)(q23;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... The patient presented with fever and chills for 10 days. He had multiple 0.5 to 1.0 cm lymph nodes on bilateral necks, axillary and inguinal areas. He had no hepatosplenomegaly. His initial blood counts were HB 10.3 gm/dL, WBC 579.0 x 109L with 97% blasts, and platelet 37.0 x 109L. ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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