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Molecular Biology Primer Part 2 ()
Molecular Biology Primer Part 2 ()

... • The amino acids have very different chemical properties; they interact with each other after the protein is built • This causes the protein to start folding and adopting it’s functional structure • Proteins may fold in reaction to some ions, and several separate chains of peptides may join togethe ...
Brooker Chapter 10
Brooker Chapter 10

... Three types of DNA sequences are required for chromosome replication and segregation ...
11.1 HL Immune System Part 1
11.1 HL Immune System Part 1

... primary response, some cells stop dividing and secreting antibody and become memory cells. • Large numbers of memory cells remain in the body for a long time… • …they are capable of producing large amounts of ...
Schedule of Lecture and Laboratory Sessions
Schedule of Lecture and Laboratory Sessions

... 9. To contrast nutritional, conditional, and resistance mutations in bacteria 10. To discuss the use of nutritional mutants (auxotrophs) in the study of bacterial conjugation 11. To describe parasexual mating (conjugation) between F+ and F- bacteria 12. To explain the F factor, what it encodes, and ...
antigen processing and presentation
antigen processing and presentation

... T cells recognize peptide fragments which have been processed and presented by MHC molecules on APC. The MHC class I and class II molecules present peptides derived from endogenous and exogenous antigens, respectively. CD4 cells recognize antigen plus class II MHC molecules while CD8 cells recognize ...
DNA replication limits…
DNA replication limits…

An artifact in studies of gene regulation using β
An artifact in studies of gene regulation using β

... experiment by sequencing candidate plasmids. However, the frequency of occurrence of the artifact reduces the efficiency of detecting bona fide transcription factors and increases DNA sequencing costs. These problems can be avoided by choosing plasmids or other vectors that do not encode the a-peptide ...
Cytoplasmic inheritance
Cytoplasmic inheritance

... encode ~ 100 proteins, 4 rRNA &~30 tRNA 5 classes of proteins 1. ribosomal & other proteins involved in translation 2. proteins involved in transcription 3. proteins involved in photosynthesis 4. proteins involved in respiration 5. ORFs (open reading frames) sequences capable of encoding proteins bu ...
Chap 4 Chemical Synhesis Sequencing and Amplification of DNA
Chap 4 Chemical Synhesis Sequencing and Amplification of DNA

... of a known protein.  May need to change 2 or more a.a. which are far apart in the linear sequence but are in proximity as a result of protein folding.  3-D structures are important for prediction. Bioinformatics can help predict on the basis of deduced a.a. sequence  simplifying the task of produ ...
Ch - TeacherWeb
Ch - TeacherWeb

... 4. RNA processing: mRNA code is shorter than the DNA code from which it was made. a. introns (intervening sequences): DNA code sequences that do not appear in the final mRNA. b. Exons: DNA codes sequences that do appear in the final mRNA c. Introns are removed in eukaryotes from the pre-mRNA, have ...
BME 301 - Rice University
BME 301 - Rice University

... Immuno-compromised individuals can get infection from carrier Carrier must be one that individuals are not already immune to Cannot make booster vaccines with carrier (must use different carrier for booster) ...
Eukaryotic Cell Structure Quiz #1
Eukaryotic Cell Structure Quiz #1

... proteins to do two jobs at once: blocking viruses and alerting the immune system that viruses are present. ...
L26_ABPG2014
L26_ABPG2014

... ectopic site in double-stranded DNA. Inefficient nicking of the antisense strand forms the primer for full-length cDNA synthesis by the RT with completion of intron insertion by DNA repair. The mechanism on the right begins with reverse splicing into the ectopic site at a replication fork. cDNA synt ...
DNA to Protein - byrdistheword
DNA to Protein - byrdistheword

... set of rules (see the chart) used to specify which amino acid is used during protein synthesis Here is a chart of the genetic code -> DNA codon: TAC mRNA: Amino Acid ...
notes - local.brookings.k12.sd.us
notes - local.brookings.k12.sd.us

... expressed (made into RNA) at any given time. How does the cell decide which will be turned on and which will stay “silent”? You already know about _____________ regions that show RNA polymerase where to start. There are other ______________________ that control whether a gene is ON or OFF. ...
pGLO Transformation SV
pGLO Transformation SV

... help plants survive difficult climatic conditions, insect damage and increase their nutrients. Toxic chemical spills are often controlled by transformed bacteria. Currently, many diabetics rely on insulin made from bacteria transformed with the human insulin gene. Scientists use transformation as a ...
New Strategies for Vaccine Development - Initial Set Up
New Strategies for Vaccine Development - Initial Set Up

Microbiology: A Systems Approach, 2nd ed.
Microbiology: A Systems Approach, 2nd ed.

... • Involve primarily the T-cell branch of the immune system • Symptoms arise one to several days following the second contact with an antigen • Result when T cells respond to antigens displayed on self tissues or transplanted foreign cells • Infectious Allergy – Example: tuberculin reaction ...
Concepts of Genetics
Concepts of Genetics

... During the eight years following publication of the Hershey–Chase experiment, additional research using bacterial viruses provided even more solid proof that DNA is the genetic material. In 1957, several reports demonstrated that if E. coli is treated with the enzyme lysozyme, the outer wall of the ...
B cell
B cell

...  Development of B cells takes place in the bone marrow and completes after activation with Ag in secondary lymphoid organs. Pluripotent hematopoietic stem cell (CD 34) Progenitor B cell - begin recombination processes which lead to a large number of clones B lymphocytes with individual specific BCR ...
The Immune Response Immunity
The Immune Response Immunity

... binding to their surface and neutralize toxins by blocking their active sites. 4. Antibody-dependent cell-mediated cytotoxicity: Used to destroy large organisms (e.g.: worms). Target organism is coated with antibodies and bombarded with chemicals from nonspecific immune cells. 5. Complement Activati ...
Pathogens and the immune system
Pathogens and the immune system

... • Have B cell receptors on surface • 100 million different types of B cells, each with different surface receptors • B cell receptors are so diverse they can recognize every organic molecule ...
The Immune System
The Immune System

... The Immune System. What’s up with that. ...
lecture08_C
lecture08_C

...  Recognizes antigens (molecular signatures) specific for each pathogen  Effective against both intra- and extracellular pathogens  Two main components: Humoral immunity - Relies on Antibodies produced by B-lymphocytes - Fights pathogens outside of cells ...
Basic Genetics Notes
Basic Genetics Notes

... • Genes are located on chromosomes • You have 23 pairs of chromosomes ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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