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L tarentolae
L tarentolae

... It consists of a fully eukaryotic protein expression machinery with posttranslational modifications, including eukaryote glycosylation, phosphorylation and disulfide bond formation. The gene of interest is cloned into shuttle vectors allowing, first, the cloning in E. coli and then, the expression i ...
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DNA vaccination



DNA vaccination is a technique for protecting an animal against disease by injecting it with genetically engineered DNA so cells directly produce an antigen, resulting in a protective immunological response. Several DNA vaccines have been released for veterinary use, and there has been promising research using the vaccines for viral, bacterial and parasitic diseases, as well as to several tumour types. Although only one DNA vaccine has been approved for human use, DNA vaccines may have a number of potential advantages over conventional vaccines, including the ability to induce a wider range of immune response types.
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