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Blair, Stuart: A review of the Gene Ontology: past developments, present roles, and future possibilities
Blair, Stuart: A review of the Gene Ontology: past developments, present roles, and future possibilities

... Stuart  Blair  –  BioC  218  Final  Paper  –  Fall  2010   ...
clin exp rheum 27/1 - Clinical and Experimental Rheumatology
clin exp rheum 27/1 - Clinical and Experimental Rheumatology

... Cardiovascular (CV) disease due to accelerated atherosclerosis constitutes the main cause of mortality in patients with rheumatoid arthritis (RA) (1). Both traditional and nontraditional risk factors contribute to this increased CV risk (2). In this regard, chronic inflammation and genetic susceptibi ...
trp
trp

... of lactose present.  Effector = level of lactose trp Operon  Transcription repressed when high levels of tryptophan present.  Effector = level of tryptophan ...
38891
38891

... • Many different methods exist for finding groups and patterns in data (including some I haven’t mentioned). • Many different parameters can be used in those methods. • Caution should be exercised in interpreting the results. ...
Basic Principles of Heredity Notes AP Biology Mrs. Laux
Basic Principles of Heredity Notes AP Biology Mrs. Laux

... 3. a gene at one locus acts as an “on/off switch” for a gene at another locus 4. epistatic genea gene that has the ability to allow expression of suppression of the other gene 5. occurs often in pigmentation 6. ex: micegene for pigment deposition (c) is epistatic to gene for melanin (pigment) prod ...
PPT
PPT

... An important topic in microarray data mining is to bind transcriptionally modulated genes to functional pathways or how transcriptional modulation can be associated with specific biological events such as genetic disease phenotype, cell differentiation etc. However, the amount of functional annotati ...
Document
Document

... expressed in E. coli cells grown in medium containing glucose or glucose + lactose but only in medium containing lactose and no glucose. ...
Transgenic Mice in Immunobiology
Transgenic Mice in Immunobiology

... Mansour S.L., Thomas K.R. and Capecchi M.R. (1988). Disruption of the Proto-Oncogene int-2 in Mouse Embryo-Derived Stem Cells: A General Strategy for Targeting Mutations to Non-selectable Genes. Nature 336, 348–352. [The generation of a general strategy to enrich for cells in which homologous geneta ...
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File

... amount of SXL protein that can begin the female-specific splicing process. If this promoter is inactivated, then no female-specific splicing will occur. Thus, XX flies will be in trouble (they die due to problems in dosage compensation as well as having ambiguous secondary sexual characteristics). B ...
OSIRIS: a tool for retrieving literature about sequence variants
OSIRIS: a tool for retrieving literature about sequence variants

... Methods section for details). All data are provided with their corresponding links to the NCBI databases. For instance, the OSIRIS search for the HTR2A gene found 255 non-coding and 7 coding variants, and assigned 160 articles to the 7 coding variants. Some articles were annotated to more than one v ...
Browser Exercises I
Browser Exercises I

... Explore the ruler tool. Click on the ruler to engage then drag it across the window. The ruler tool displays the nucleotide coordinates of the ruler’s solid center line. This is very useful for comparing between the annotation data track and others that we will add later. ...
NCEA Level 2 Biology (91159) 2015
NCEA Level 2 Biology (91159) 2015

... Biologists use yarrow plants that have identical genotypes because if there are any changes to their phenotype, it can be attributed to environmental factors. The phenotype of an organism results from the interaction between the genotype and the environment. The phenotype is a composite of the genot ...
Lazarus and doppelganger genes
Lazarus and doppelganger genes

... • Highest proportion of HGT genes are in bdelloid rotifers • 10% of transcripts ...
Workshop_I
Workshop_I

... • Adjust the significance cutoff for multiple testing. ...
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... interaction between food and predators that acted primarily through changes in reproduction. Using the data, discuss this hypothesis. ...
SCI 30 UA CH 2.5 Genetic Technologies
SCI 30 UA CH 2.5 Genetic Technologies

... genes spliced from two or more organisms Enzymes are used to cut a sample of the healthy individual’s DNA into pieces. gene therapy: the technique of using a vector, such as a virus, to repair or replace The segment of DNA with the needed gene is isolated, and the gene is inserted defective genes in ...
Abiel Rindisbacher
Abiel Rindisbacher

... • ‘‘Loc1  is  required  for  the  assembly  of  ribosomes  containing   a  specific  subset  of  duplicated  ribosomal  proteins  and  this   specialized  ribosome  is  required  for  the  regulated   transla?on  of  ASH1  mRNA’’   • The  mo ...
presentation (spanish ppt format, 4.7 MB)
presentation (spanish ppt format, 4.7 MB)

... Reports of unexpected outcomes in experiments performed by plant scientists in the United States and the Netherlands in the early 1990s. In an attempt to alter flower colors in petunias, researchers introduced additional copies of a gene encoding chalcone synthase, a key enzyme for flower pigmentati ...
control of the drosophila body pattern
control of the drosophila body pattern

... Using the homeobox as a probe, genes homologous to Hox from many species including vertebrates have been isolated. Study of these genes gave a spectacular demonstration for the universality of developmental principles. In the mouse, dominant gain and loss of function mutations result in segmental tr ...
Document
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... investigated in this study. RT-PCR analysis revealed that although the primers amplified well from the genomic DNA template, the primers failed to amplify the cDNA expressed at the collection time points during conjugation to high enough levels to be detected in this study. This most likely suggests ...
Selecting Informative Genes from Microarray Dataset Using Fuzzy
Selecting Informative Genes from Microarray Dataset Using Fuzzy

... Table 1. Fig. 3 shows the test errors of linear SVM classifiers on gene subsets selected respectively by SVM-RFE and proposed method. As shown in table 1 and fig. 3 using fuzzy relational clustering for omitting redundancy of co-expressed genes leads to better performance with fewer genes. The fuzzy ...
Eigen-R2 for dissecting variation in high
Eigen-R2 for dissecting variation in high

... obvious choice is to simply take the mean of the R2 values, which we refer to as mean-R2 . However, this measure may be vulnerable to technical artifacts in the data. For example, in a gene expression study, many genes will not be expressed. For such genes, the expression measurements are low, resul ...
A Variable Number of Tandem Repeats Locus with!, the Human
A Variable Number of Tandem Repeats Locus with!, the Human

... have been detected, characterized by SstI fragments of 2.75, 2.70, 2.65, 2.60, or 2.50 kb corresponding to BamHI fragments of 3.45, 3.40, 3.35, 3.30, or 3.20 kb (3, 5). The distribution of these alleles among 143 unrelated individuals was found to be skewed with 250 (87.4%) chromosomes having 2.70/3 ...
Gene Regulatory Network Discovery from Time-Series - kedri
Gene Regulatory Network Discovery from Time-Series - kedri

... Gene regulatory network is one of the two main targets in biological systems because they are systems controlling the fundamental mechanisms that govern biological systems. A single gene interacts with many other genes in the cell, inhibiting or promoting directly or indirectly, the expression of so ...
Gen660_Lecture3A_Ortho
Gen660_Lecture3A_Ortho

... Orthology & Paralogy (etc. etc.) ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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