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The ApoE gene fact sheet
The ApoE gene fact sheet

... people and the impact that these differences may have on our health and risk of disease. At the University of Reading, we are interested in how these variations affect people’s response to foods. For this reason, in some of our studies we ask you to provide a blood sample that we use to determine wh ...
Test Information Sheet
Test Information Sheet

... For those individuals with clinical features suggestive of a ZRS-related disorder, using genomic DNA obtained from the submitted biological material, bi-directional sequence of the ZRS region is obtained and analyzed. If no mutation is identified by sequence analysis, deletion/duplication analysis c ...
4132010
4132010

... C Napoli, C Lemieux, and R Jorgensen ...
Variation due to change in the individual genes
Variation due to change in the individual genes

... mechanism of autocatalysis resides within the genes rather than in the “protoplasm.” Meanwhile, the method is worth following up, simply because it is one of our few conceivable modes of approach to an allimportant problem. It may also be recalled in this connection that besides the genes in the chr ...
Integrons: natural tools for bacterial genome evolution
Integrons: natural tools for bacterial genome evolution

... among the bacterial species in which they are found (Figure 1) [14••]. Thus, the establishment of SIs likely pre-dates speciation within the respective genera, indicating that integrons are ancient structures that have been involved in the evolution of bacterial genomes for hundreds of millions of y ...
Exclusion of the neuronal nicotinic acetylcholine receptor 7 subunit
Exclusion of the neuronal nicotinic acetylcholine receptor 7 subunit

... and periodic catatonia share bipolarity as a common feature, thus providing evidence that pleiotrophic effects of different mutations within one gene may be responsible for different clinical phenotypes. However, a potential clustering of more than one disease gene in this region cannot be ruled out ...
Conserved amino acid sequences confer nuclear localization
Conserved amino acid sequences confer nuclear localization

... Prophet of Pit-1 (PROP1) is a homeodomain transcription factor essential for development of the mammalian anterior pituitary gland. Studies of human patients and animal models with mutations in their Prop1 genes have established that PROP1 is required for the correct development or sustained functio ...
Genome duplication, divergent resolution and
Genome duplication, divergent resolution and

... clusters as, for example, humans. Additional evidence favouring the fish-specific genome duplication hypothesis comes from comparative mapping studies, which have identified a large number of mammalian genes with two zebrafish ‘co-orthologs’19–21. Furthermore, most of these zebrafish co-orthologs ar ...
Figure 1 - York College of Pennsylvania
Figure 1 - York College of Pennsylvania

... •Neurons have an altered endoplasmic reticulum morphology. •Microarray analyses on INCL brain tissues shows an upregulation of inflammatory genes. •The post-mitotic nature of neurons may contribute to their selective degeneration. ...
DNA Technology and Genomics  I.
DNA Technology and Genomics I.

... The typical human gene specifies several different polypeptides by using different combinations of exons. D. Nearly all human genes contain several exons, and an estimated 75% of these multiexon genes are alternatively spliced. Along with this is additional polypeptide diversity via posttranslationa ...
19. Gene Regulation
19. Gene Regulation

... Lecture Outline: 1. Transcriptional control 2. Lactose operon: negative control 3. Lactose mutants 4. Positive control (optional) Lecture: 1. Transcriptional control Gene regulation: Control of when, where and under what conditions genes are transcribed and translated. Transcriptional regulation ...
Genetics - Miami Beach Senior High School
Genetics - Miami Beach Senior High School

... Mendel studied seven of these traits After Mendel ensured that his truebreeding generation was pure, he then crossed plants showing contrasting traits. He called the offspring the F1 generation or first filial. ...
Mapping Regulatory Network from a Model Organism to a Non
Mapping Regulatory Network from a Model Organism to a Non

... their regulatory relationships, which indicate how a gene or a group of genes affect (inhibit or activate) production of other gene products. Some organisms such as yeast, Arabidopsis thaliana and fruit fly have been investigated very thoroughly by biologists as model organisms, being simpler and ha ...
Supporting Information
Supporting Information

... were grown in LB media (1% tryptone, 1% NaCl, 0.5% yeast extract). Media were solidified by ...
Leukaemia Section t(3;5)(q26;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(3;5)(q26;q34) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... ZBTB16/PLZF, ZFPM2/FOG2, JNK and the PI3K/AKT pathway. Role in cell cycle progression, likely to be cell-type dependant; antiapoptotic factor; involved in neuronal development organogenesis; role in hematopoietic differentiation. ...
Phylogenetics Topic 2: Phylogenetic and genealogical homology
Phylogenetics Topic 2: Phylogenetic and genealogical homology

... Previously, we examined how rooted phylogenies provide a framework for distinguishing similarity due to common ancestry (HOMOLOGY) from non-phylogenetic similarity (ANALOGY). Here we extend the concept of phylogenetic homology by making a further distinction between a HOMOLOGOUS CHARACTER and a HOMO ...
PDF - Biology of Sex Differences
PDF - Biology of Sex Differences

... the variability of phenotypes between gonad-intact male and female mice. They found that females are not more variable than males and that under some conditions males are more variable than females. The amount of male variability was reduced in mice housed as individuals, supporting the idea that ph ...
Individual nucleosomes are released by digestion of chromatin with
Individual nucleosomes are released by digestion of chromatin with

... • A hypersensitive site is – a short region of chromatin detected by its extreme sensitivity to cleavage by DNAase I and other nucleases – it is an area from which nucleosomes are excluded. ...
EXPLORING DEAD GENES
EXPLORING DEAD GENES

... processing in the worm genome Found large uncharacterized gene family that makes up 2/3 of dead genes Arms of chromosome are an unreliable for encoding genes but more likely to spawn new proteins ...
video slide
video slide

... (b) Acetylation of histone tails promotes loose chromatin structure that permits transcription ...
Incomplete Dominance, Codominance, and ABO Blood Types
Incomplete Dominance, Codominance, and ABO Blood Types

... you can be anywhere from 5’ to 7’ tall, there is no tall or short in humans! ...
mandelian genetics - study
mandelian genetics - study

... Two pairs of genes affect comb type in chickens. When both genes are recessive, a chicken has a single comb. A dominant allele of one gene, P , gives rise to pea comb. Yet a dominant allele of the other (R) gives rise to rose comb. An epistatic interaction occurs when a chicken has at least one of b ...
Genetic markers, marker assisted selection
Genetic markers, marker assisted selection

... ¾ ¾ ¾ ¾ ...
15 - Centre for Genetics Education
15 - Centre for Genetics Education

... will be inactivated only if they are passed down through a sperm cell. Imprinting will then occur again in the next generation when that person produces his or her own sperm or eggs. ...
Name Monohybrid Cross Homework Problems Answer the following
Name Monohybrid Cross Homework Problems Answer the following

... Name __________________________ ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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