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Genetic Engineering
Genetic Engineering

... Finding the location of certain genes on chromosomes The arrangement of the nitrogen base pairs (A,T,C and G) determines what an organism looks like Human Genome Project ...
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... Your answers must be well organized and concise. You have 75 minutes to complete the exam. 1) (10 points) Draw the mechanism of the reaction catalyzed by DNA polymerase that occurs between deoxyribose at the end of a DNA chain and a deoxyribonucleoside triphosphate. Include the chemical structure of ...
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... The DNA is wrapped around the basic proteins called histones forming nucleosomes connected by linker DNA. Repetitive sequences probably play a key role in stabilizing this structure. Chromatin Remodeling and Histone Acetylation: Histone acetylation is known to change the structure of the chromatin. ...
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Epigenomics

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell (Russell 2010 p. 217 & 230). Epigenetic modifications are reversible modifications on a cell’s DNA or histones that affect gene expression without altering the DNA sequence (Russell 2010 p. 475). Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis (Russell 2010 p. 597). The study of epigenetics on a global level has been made possible only recently through the adaptation of genomic high-throughput assays (Laird 2010) and.
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