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Epigenetic Regulation of the Glucocorticoid receptor in human brain
Epigenetic Regulation of the Glucocorticoid receptor in human brain

... cellular phenotype caused by mechanisms other than changes in the underlying DNA nucleotide sequence. DNA methylation and histone deacetylation are two processes which can cause these heritable changes. ...
Microbial GeneticsIII MB - E
Microbial GeneticsIII MB - E

... 5. This type of recombination does not require homologous sequences and is important for the integration of viral genomes into bacterial chromosomes (1) general recombination (2) site-specific recombination (3) replicative recombination 6. This type of recombination does not require homologous seque ...
Although patients are responsible for travelling to the referral centres
Although patients are responsible for travelling to the referral centres

... phone: 0191 282 0841 fax: 0191 282 0840 email [email protected] ...
Molecular Genetics II (cont.) Mutation
Molecular Genetics II (cont.) Mutation

... Alleles of a gene commonly differ by only a single nucleotide pair in DNA. The nucleotide change results in an amino acid change in the protein and a change in the properties of the protein. Sickle-cell anemia Sickle-cell anemia is due to a recessive gene. Homozygotes for the sickle-cell allele have ...
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Access Slides

... A common multi-protein machinery transcribes many thousands of genes coding for proteins in eukaryotes. Recent structural studies have provided Information about the Pol II-based eukaryotic transcription machinery and about Mediator, the complex involved in transcription regulation during initiation ...
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... apparently because of a new enzyme in the liver. Using various molecular biological techniques,  you successfully clone the entire gene for this enzyme and name it drunk’n.  You would like to  perform some experiments on the drunk’n protein to determine its alcohol‐metabolizing  activity in a test t ...
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Heredity Study Guide Answers
Heredity Study Guide Answers

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Heredity Study Guide
Heredity Study Guide

... Selective breeding: specific traits are selected in the parents in order to ensure they are passed to the offspring & the genes are not actually altered 20. List some positive uses for selective breeding. The traits can easily be predicted. You can produce offspring that can serve a specific purpose ...
Eukaryotic Genes and Genomes I
Eukaryotic Genes and Genomes I

... organism’s genome. The average protein is about 300 amino acids long, requiring 300 triplet codons, or roughly 1Kb of DNA. Thus it makes sense that to encode 4,200 genes E. coli requires a genome of 5 million base pairs. However, the human genome encodes about 22,500 proteins, and this should requir ...
DNA Recombination - Home - KSU Faculty Member websites
DNA Recombination - Home - KSU Faculty Member websites

... exchange between molecules with extended sequence homology. For example, transformation and conjugation between related bacterial strains. Site-specific recombination refers to DNA recombination between molecules that shared limited regions of sequence homology. ...
Exam Review 4B - Iowa State University
Exam Review 4B - Iowa State University

... a. High glucose, high levels of cAMP b. High glucose, high levels of CAP c. Low glucose, low levels of cAMP d. Low glucose, high levels of cAMP 8. When the cAMP-CAP complex is bound which of the following takes place? a. Polymerase binds the lacP more efficiently b. Polymerase if unable to bind to t ...
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Epigenomics

Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous to genomics and proteomics, which are the study of the genome and proteome of a cell (Russell 2010 p. 217 & 230). Epigenetic modifications are reversible modifications on a cell’s DNA or histones that affect gene expression without altering the DNA sequence (Russell 2010 p. 475). Two of the most characterized epigenetic modifications are DNA methylation and histone modification. Epigenetic modifications play an important role in gene expression and regulation, and are involved in numerous cellular processes such as in differentiation/development and tumorigenesis (Russell 2010 p. 597). The study of epigenetics on a global level has been made possible only recently through the adaptation of genomic high-throughput assays (Laird 2010) and.
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