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Fact sheet (PDF, 58.54 KB) (opens in a new window)
Fact sheet (PDF, 58.54 KB) (opens in a new window)

... Recent research at the University of Western Sydney demonstrates transcriptional interference between coding genes. These sets of interacting transcription units (SITRUS) have many unexpected functions with regards to gene expression and disease. Scientists at UWS have developed a simple siRNA metho ...
Name
Name

... Directions: Use this as a study guide for your next exam. Typically 80-90% of the exam questions come from this sheet. Other questions may come from labs, online activities and news articles which have been discussed in class. DNA and Chromosomes ...
Gene Regulation in Eukaryotes Webquest
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... the nucleus. Inactive heterochromatin DNA is methylated and tightly wound around acetylated histones. Recap: Describe an inactive domain of DNA: ___________________________________________________________________________________________ _______________________________________________________________ ...
Chromatin Remodeling - Molecular Pharmacology
Chromatin Remodeling - Molecular Pharmacology

... to a particular drug action or behavior has been shown using targeted approaches (i.e., mutant mice, viral vectors, RNAi), demonstrating the functional significance of altered gene expression. The binding sites and acute actions of psychotropic drugs occur primarily at neurotransmitter receptors or ...
Epigenetics: Histone Modification III
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Gene Section HTATIP (HIV-1 Tat interacting protein, 60kDa) in Oncology and Haematology
Gene Section HTATIP (HIV-1 Tat interacting protein, 60kDa) in Oncology and Haematology

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CISC 3250: Systems Neuroscience Homework 5 due April 27 or

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... The SANT domain is a nucleosome recognition module found in transcriptional regulatory proteins, including chromatin-modifying enzymes. It shows high functional degeneracy between species, varying in sequence and copy number. Here, we investigate functions in vivo associated with two SANT motifs, SA ...
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lec#18
lec#18

... • Reversible , heritable changes in gene expression without mutation. • Two types: Histone modifications and DNA methylation. ...
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Epigenetics Theory www.AssignmentPoint.com In genetics

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... Motor symptoms in one particular mouse model improved within a month of treatment, and continued to improve until the HD mice looked no different from normal mice. When older mice with more symptoms were treated, their motor and behavioral symptoms did improve, but it took much longer for improvemen ...
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Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
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