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OverviewCerebellum
OverviewCerebellum

... For normal operation of the VOR, the flocculus is not very important. A major discovery was that the VOR could change if the visual input was perturbed. The classic method for perturbing the visual input was to put a pair of prisms over the eyes. When this is done a head rotation will result in an i ...
Supplementary Information (doc 7548K)
Supplementary Information (doc 7548K)

... Supplementary Figure 7 | Transcription factor binding site enrichment by community. Sets of genes from within the positively correlated GATA2 network that were identified as belonging to sub-networks (using the algorithm of (Blondel et al., 2008)) were generated. Ref_seq identifiers for these gene ...
(RBPs) have been demonstrated to perform central roles in these
(RBPs) have been demonstrated to perform central roles in these

... Department of Plant Science, Seoul National University, Seoul 151-921, Korea Hybrids and polyploids occur in many flowering plants. In particular, hybridization between different species or genus may produce novel plant species, which is best exemplified in the Brassica family. However, many intersp ...
Memory disorders in children in school
Memory disorders in children in school

... 2.Follow a routine and systemic daily schedule. 3.Use memory tools such as big calendars, to-do lists & notes to youself. ...
BCH 550 Chromosome - Home - KSU Faculty Member websites
BCH 550 Chromosome - Home - KSU Faculty Member websites

... A form= Rt handed;Formed in dehydrated state; 11 bp/turn; Pitch= 2.3nm Z form= Left handed; 12 bp/turn; Pitch= 3.8 nm; Some nucleotide sequences form Z form; Short Z sequences may occur in cells. May be involved in regulation of gene expression. ...
Gene Section HIC1 (hypermethylated in cancer 1) Atlas of Genetics and Cytogenetics
Gene Section HIC1 (hypermethylated in cancer 1) Atlas of Genetics and Cytogenetics

... HIC1 is a transcriptional repressor belonging to the BTB/POZ and Krüppel C2H2 family (44 proteins in the human genome). HIC1 interacts with the corepressor CtBP through a conserved GLDLSKK motif in the central region. This central region also contains a SUMOylation site MK314HEP which is important f ...
Deciphering the role of DNA methylation in multiple sclerosis
Deciphering the role of DNA methylation in multiple sclerosis

... environmental and genetic factors [1]. Epigenetics may be the bridge between genotypes, environmental exposures, and phenotypes. Epigenetic modifications are heritable, reversible alterations in gene expression, which do not affect gene sequence. They depend on environmental and biological condition ...
Sir Alec Jeffreys minisatellites
Sir Alec Jeffreys minisatellites

... Unit - 15-400 bp (average about 20). Repeat - Generally 20-50 times (1000-5000 bp long). Location - Generally euchromatic. Examples - DNA fingerprints. Tandemly repeated but often in dispersed clusters. Also called VNTR’s (variable number tandem repeats). Human λ33.1 minisatellite (62 bp) AAGGGTGGGC ...
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Microarrays Central dogma
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Acquired Traits Revisited
Acquired Traits Revisited

... cutting off the tails of mice for several generations and breeding only from them, the German biologist August Weissman (1833–1914) reported in his 1891 book that the tail lengths of all the descendants grew to normal length. Many people assumed from these experiments that if characteristics acquire ...
Simulating Population Genetics
Simulating Population Genetics

... • Relax the assumption that all alleles are equally fit. Choose one of your alleles to be lethal recessive; that is, if the a allele is lethal recessive, aa mice die at birth but Aa and AA mice don’t. How does this change the equilibrium? Can any starting conditions change the final equilibrium? In ...
Gene Section THBS1 (thrombospondin-1) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Gene Section THBS1 (thrombospondin-1) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... TSP1 is expressed in many tissues during embryonic development but has limited expression in the healthy adult. TSP1 is the most abundant protein in alpha granules of platelets, but normal plasma levels are very low (typically 100-200 ng/ml). Expression in other cell types is induced by wounding, du ...
Measuring Gene Expression
Measuring Gene Expression

... Because each cycle of PCR requires the denaturization step the number of PCR cycles is under experimental control. Hence, the quantity of PCR product at the end of some number of cycles can be used to estimate the initial quantity. The estimate is usually improved by also amplifying a "control" prod ...
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... Rice contains genes for production of beta carotene (Vitamin A) in the green parts as a photosynthetic pigment so it is not eaten Elsewhere in the plant, the genes are switched off Two genes needed to be added to switch on the beta carotene gene in the rest of the plant The genes added were Phytoene ...
Does the Gene Affect Our Actions or Feelings?
Does the Gene Affect Our Actions or Feelings?

... but only a third of mans is less active It can tell the brain to control chemicals and nerotransmitters that let brain cells communicate to each other ...
Schedule of Lecture and Laboratory Sessions
Schedule of Lecture and Laboratory Sessions

... 30. Analyze X chromosome inactivation using the following concepts: Barr body, dosage compensation, XIC, XIST gene (calico cat example of female mosaic). 31. Relate the number of Barr bodies to number of X chromosomes in a cell 32. Describe the cell-culturing technique of karyotyping. Review a karyo ...
GENE GENE INTERACTION DOMINANCE
GENE GENE INTERACTION DOMINANCE

... It is also known as duplicate gene . When two gene pairs seem to be identical in function ,either dominant gene or both dominant gene together give the same effect. Such genes are called duplicate genes and the type of epistasis is called dominant epistasis. ...
Regulation of Gene Expression
Regulation of Gene Expression

... passed from one generation to the next. But studies of monozygotic twins show they can be altered. Comparison of DNA in such twin pairs shows that in 3-year-olds, DNA methylation patterns are virtually the same. By age 50, when twins have been living in different environments—the patterns are differ ...
group3_slides
group3_slides

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emboj7601952-sup
emboj7601952-sup

... family coding for three highly homologous RING fingers proteins, referred to as MuRF1,2 and 3; also called RNF 28-30; or TRIM 63, 55, 54). The three MuRFs share highly conserved N-terminal RING finger domains, followed C-terminally by a MuRF family conserved motif (MFC), a B-box, and a coiled-coil r ...
Genome Organization
Genome Organization

... – Provide the first level of packaging for the chromosome; compact the chromosome by a factor of approximately 7 – DNA is wound around histone proteins to produce nucleosomes; stretch of unwound DNA between each nucleosome ...
Study Questions for 2nd hourly exam
Study Questions for 2nd hourly exam

... tissue) does not prove that the substance actually performs this function in vivo. What other evidence should be found to suggest the substance is the actual inducing agent? (For example, retinoic acid was for some time believed to be the morphogen of the ZPA (zone of polarizing activity). What do w ...
Synaptogenesis and the Proteins that influence its Connectivity
Synaptogenesis and the Proteins that influence its Connectivity

... the years of their life. One is able to hold more information, pay more meaningful attention to their environment, and as an adult or an older child one is able to learn complex subjects much more quickly than that of an elementary school age child. This is all accomplished through a process called ...
Exam 2 Full v3 Bio200 Win16
Exam 2 Full v3 Bio200 Win16

... In the diagram, a snapshot of a single chromosome is shown along with RNA polymerase and ribosomes. There are RNAs of various sequences, as well as three different proteins. Use this diagram to answer the questions on pages 2-3. /5 1a) At the moment of this snapshot shown to the right, which of the ...
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Epigenetics in learning and memory

While the cellular and molecular mechanisms of learning and memory have long been a central focus of neuroscience, it is only in recent years that attention has turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation often involves the physical marking (chemical modification) of DNA or associated proteins to cause or allow long-lasting changes in gene activity. Epigenetic mechanisms such as DNA methylation and histone modifications (methylation, acetylation, and deacetylation) have been shown to play an important role in learning and memory.
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