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Christine Yiwen Yeh - The Second Draft: The Human Epigenome for novel Diagnoses and Therapies
Christine Yiwen Yeh - The Second Draft: The Human Epigenome for novel Diagnoses and Therapies

... diseases. One specific example is prostate cancer: there are potential clinical applications of epigenetic management. For example, markers of DNA hypermethylation are subject to many studies as potential complementary diagnostic tools, prognostic factors, and predictors of responses to treatment. ...


... The environment of a cell has changed. Let’s say that there is suddenly lactose sugar present! The cell must make loads of lactase right away. Name some ways that the cell can gear up production of lactase quickly. To illustrate the impact that mutations can have on a living thing, some made-up numb ...
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Ch 3 The Molecules of Cells
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... 5. What happens if lactose levels are low? Put the following list in order (1-5) RNA polymerase is blocked from transcribing the genes for the lactose metabolizing enzymes When RNA polymerase binds to the promoter, it cannot get past the LacI repressor protein The enzymes β-galactosidase, β-galacto ...
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... the identification of many oncogenes. From this work, researchers have also learned that normal cells contain proto-oncogenes that usually play a role in cell division. This suggests that oncogenes exert their effects by upsetting the cell division process. In particular, it appears that oncogenes a ...
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... of DNA replication and genomic stability by negatively modulating expression of E2F target genes which are involved in promoting the progression of S and G2 phases (Lo et al., 2010; Lo et al., 2012). These lines of evidence suggest that FOXF1 is an epigenetically silenced tumor suppressor gene in br ...
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Nihill, G. Gene testing - Clearinghouse for Sport
Nihill, G. Gene testing - Clearinghouse for Sport

... for individual athletes, or be a factor in selection, or help to identify athletes who are prone to particular sportrelated injuries. But there are no short cuts to elite sports performance. The consensus is that gene testing could be a guide to sports performance — but not the single determinant of ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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