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Journal of Bacteriology
Journal of Bacteriology

... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...
Identification of prokaryotic homologues indicates an endosymbiotic
Identification of prokaryotic homologues indicates an endosymbiotic

... the oxidase in vitro is clearly regulated by a redox-sensitive intersubunit disulfide bond and also by a-keto acids, pyruvate in particular (Umbach et al., 1994). Using site-directed mutagenesis, it was shown that a highly conserved cysteine residue located at the N-terminus of the plant protein is ...
Cockayne Syndrome group B protein interacts
Cockayne Syndrome group B protein interacts

... TPP1 and POT1, functions not only to regulate telomere length maintenance but also to protect natural chromosome ends from being recognized as damaged DNA (1,2,4). Telomeric DNA has been shown to be transcribed into a large non-coding telomere repeat-containing RNA (5), referred to as TERRA, which i ...
Preneoplastic Lesions of the Lung
Preneoplastic Lesions of the Lung

... rugae and, rarely, a polypoid conformation. In the remaining cases, the site of the bronchial mucosa involved cannot be distinguished from normal tissue. CIS may or may not be associated with epithelial thickening. Cytological aberrations are extreme ± similar to those visible in invasive cancer. Mi ...
File
File

... the ability to isolate a specific segment of DNA, modify it in a test tube, and transfer it back into the same or a different cell to create a genetically modified organism represents perhaps the most significant advance in the history of biology, with profound consequences for the future of our, an ...
DpnII - Inv. PCR of miniMos for distribution
DpnII - Inv. PCR of miniMos for distribution

... protocol because we changed and optimized several parameters which in our hands improve the reliability of inverse PCR reactions. It is the protocol that we currently (December 2012) use in the lab. Use aerosol resistant tips for all steps!! Contamination is a real problem when doing two sequential ...
Patterns of Inheritance
Patterns of Inheritance

... traits, besides sex, are controlled by genes on the sex chromosomes. These are called sex-linked traits. ¾ Traits controlled by the X are X-linked. ¾ Traits controlled by the Y are Y-linked. ¾ Since most sex-linked traits are controlled by the X, you can assume ...
TRIPTYCHON and CAPRICE mediate lateral inhibition during
TRIPTYCHON and CAPRICE mediate lateral inhibition during

... epidermis, although this particular ®nding was interpreted as an unspeci®c competition with the trichome-promoting factor GL1 (Wada et al., 1997). In this work, we report the positional cloning and molecular characterization of the TRY gene. TRY encodes a MYB-related protein with high sequence simil ...
ADVANCES IN AGRICULTURAL SCIENCES XIV (1–2)
ADVANCES IN AGRICULTURAL SCIENCES XIV (1–2)

... chronic inflammation which, aside significant discomfort to the patient, brings about severe consequences to the body’s functioning. Symptoms of the inflammation are fought against with various chemotherapeutic agents, including non-steroidal anti- inflammatory drugs, glucocorticosteroids, cytostati ...
Chromosomes
Chromosomes

... • Cell with the most spread out chromosomes is used • Chromosomes are identified with stain or FISH ▫ Staining- use chromosome specific stains ▫ FISH (fluorescence in situ hybridization)fluorescent probes are attached to chromosomes; each chromosome fluoresces a different color ...
A CRISPR-based yeast two-hybrid system for investigating
A CRISPR-based yeast two-hybrid system for investigating

... domain to the reporter genes in yeast three-hybrid necessitates three different binding interactions (e.g., DNA LexA sites • LexADBD–MCP • MS2 RNA–X • Y–GAD). In contrast, the CARRY two-hybrid system uses CRISPR/dCas9 to directly target RNA to DNA. By reducing ...
blood group systems - The Indian Immunohematology Initiative
blood group systems - The Indian Immunohematology Initiative

... GENETICS: phenotype is determined by two closely linked genes on the 1st chromosome, RHD and RHCE. A. The Rh negative phenotype is due to a deletion of the RHD gene in most Caucasians, but in other populations may be due to an inactive or partial RHD gene. B. The Rh system alleles exhibit "linkage d ...
A CRISPR-based yeast two-hybrid system for investigating
A CRISPR-based yeast two-hybrid system for investigating

... domain to the reporter genes in yeast three-hybrid necessitates three different binding interactions (e.g., DNA LexA sites • LexADBD–MCP • MS2 RNA–X • Y–GAD). In contrast, the CARRY two-hybrid system uses CRISPR/dCas9 to directly target RNA to DNA. By reducing ...
Genetic Transformation of Poinsettia (Euphórbia
Genetic Transformation of Poinsettia (Euphórbia

... In nature, A. tumefaciens will infect dicotyledonous plants to produce crown-gall disease by transferring genes coding for crown-gall into the plant (Hoekema et al. 1983; Stachel & Nester 1986). This is done by a virulence region (vir-region) located in a tumour inducing plasmid (Tiplasmid) in the A ...
Role of Lipids and Fatty Acids in Stress Tolerance in Cyanobacteria
Role of Lipids and Fatty Acids in Stress Tolerance in Cyanobacteria

... reversibly the photolytic water splitting. The ionic effect of 0.5 M NaCl is caused by the influx of Na+ ions through K+ (Na+) channels and the resultant increase in the intracellular concentration of Na+ ions and counterpart anions that are mostly Cl- ions (Allakhverdiev et al. 2000a). These change ...
Universitat Autònoma de Barcelona Faculty of Sciences, Department of Biochemistry
Universitat Autònoma de Barcelona Faculty of Sciences, Department of Biochemistry

... Raltegravir is the first in-class HIV-1 integrase inhibitor approved for the treatment of HIV-1 infected subjects. However, like all other HIV inhibitors, the emergence of drug resistance limits its clinical efficacy. Understanding the differential prevalence rate of mutations within the integrase c ...
MGF 360-17R Missing
MGF 360-17R Missing

... Trunc – 014 [MGF 110-7L/MGF 360-6L Fusion Protein]: This gene is a fusion between the MGF 110-7L ortholog and MGF 360-6L. The carboxy terminus of this fusion is shown as a small box between the 3L and 4L orthologs as the MGF 110 orthologs are outside of the scope of this diagram. The annotated ortho ...
Marfan syndrome
Marfan syndrome

... type profibrillin is not incorporated into extracellular matrix until it is converted to fibrillin 24. ...
Biopathways Representation and Simulation on Hybrid Functional
Biopathways Representation and Simulation on Hybrid Functional

... metabolic pathway (glycolitic pathway), and signal transduction (Fas ligand induced apoptosis)), which cover the basic aspects in biopathways. It is not the purpose of this paper to tune precisely the parameters appearing in the biopathways, but to show that Genomic Object Net would be a useful tool ...
Genetics
Genetics

... Each chromosome has more than two thousand alleles along its length. Alleles are directions for cells. Chromosomes come in pairs. That means alleles come in pairs, too. Each cell has two sets of directions for how the cell works. A pair of alleles that work at the same time make a gene. A zebra’s ge ...
somatic hypermutation of the 5' noncoding region of the Frequent MARTINOrrI*t,
somatic hypermutation of the 5' noncoding region of the Frequent MARTINOrrI*t,

... from chromosomal rearrangements and linkage to immunoglobulin genes. These alterations identify a mechanism of genetic instability in malignant B cells and may have been selected during lymphomagenesis for their role in altering BCL6 expression. ...
20070622084130718_2 - Trees for Life Journal
20070622084130718_2 - Trees for Life Journal

... disease may affect various ethnic groups such as the people of the Hispanic and Middle East descent, it affects those of African descent, the more. The most clinical manifestations are largely due to hemolytic processes leading to severe anemia and vasoocclusive crises resulting in pain and organ da ...
BIOLOGY OF HUMAN RESPIRATORY SYNCYTIAL VIRUS: A
BIOLOGY OF HUMAN RESPIRATORY SYNCYTIAL VIRUS: A

MycoplasMa Quality control
MycoplasMa Quality control

... Importance of routine testing Because mycoplasma can affect the phenotypic and functional characteristics of cells in vitro, the implementation of early detection methods that are rapid and sensitive is an important step towards preventing the deleterious and costly effects of mycoplasma on research ...
Guppies – Quang Anh
Guppies – Quang Anh

... gene frequency of the brightest guppies was the highest, at 0.78, and so, it proves that those are the ones seen as the most attractive by the female guppies. And although the predation, natural force, played a role in the simulation, it was overwhelmed by sexual selection and even though the bright ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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