A novel arginine substitution mutation in 1A domain and a novel 27
... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
... region have been reported.26–29 The proband of family B carries a novel duplication insertion of 27 nucleotides (1222ins27). This type of mutation is unique for a number of different reasons. Firstly, in-frame insertion or deletion mutations are extremely rare in keratin diseases (table 2), and this ...
Bowel Cancer and Inherited Predisposition
... tissue or organ in the body. A group of cells that has resulted from uncontrolled cell division and growth is called a tumour. ...
... tissue or organ in the body. A group of cells that has resulted from uncontrolled cell division and growth is called a tumour. ...
Epstein–Barr Virus and Cytomegalovirus Infections
... suggesting lytic replication of EBV in the brain in addition to latent replication (Weinberg et al. 2002a). Secondly, EBV-infected B cells are in an activated state and elaborate several proinflammatory cytokines, which can cause injury of the surrounding parenchyma (Foss et al. 1994). This injury i ...
... suggesting lytic replication of EBV in the brain in addition to latent replication (Weinberg et al. 2002a). Secondly, EBV-infected B cells are in an activated state and elaborate several proinflammatory cytokines, which can cause injury of the surrounding parenchyma (Foss et al. 1994). This injury i ...
IFN
... Patients who are always hypocomplementemic regardless of clinical disease activity may have an underlying complement deficiency! ...
... Patients who are always hypocomplementemic regardless of clinical disease activity may have an underlying complement deficiency! ...
Stumps, a Drosophila gene required for FGF-directed migrations of tracheal and mesodermal cells. Genetics 152, 307-318. pdf
... transduction pathways that lead to directed cell migrations are not well defined. Here we describe a Drosophila gene called stumps that is required for FGF-dependent migrations of tracheal and mesodermal cells. These migrations are controlled by different FGF ligands and receptors, and they occur by ...
... transduction pathways that lead to directed cell migrations are not well defined. Here we describe a Drosophila gene called stumps that is required for FGF-dependent migrations of tracheal and mesodermal cells. These migrations are controlled by different FGF ligands and receptors, and they occur by ...
A A c ca as
... This supports the notion that, in some patients, eosinophilic bronchitis and asthma represent ends of a spectrum of the same disease, and that eosinophilic bronchitis can be an early manifestation of asthma [8]. Our patient achieved a complete and long-lasting remission after a short course of predn ...
... This supports the notion that, in some patients, eosinophilic bronchitis and asthma represent ends of a spectrum of the same disease, and that eosinophilic bronchitis can be an early manifestation of asthma [8]. Our patient achieved a complete and long-lasting remission after a short course of predn ...
Root Hairs - Biological Sciences
... The TTG gene encodes a small protein with WD40 repeats (Walker et al., 1999). Although the protein sequence does not provide a clear mechanistic understanding of TTG’s role, it is known that ttg mutations can be functionally complemented by expression of the maize R cDNA (under the control of the st ...
... The TTG gene encodes a small protein with WD40 repeats (Walker et al., 1999). Although the protein sequence does not provide a clear mechanistic understanding of TTG’s role, it is known that ttg mutations can be functionally complemented by expression of the maize R cDNA (under the control of the st ...
Mary Ann Osley*, Alastair Fleming, and Cheng
... that Bre1 interacts with Rad6 and targets it to chromatin provides additional evidence that Bre1 is a bona fide E3 that directs Rad6 to its histone substrate{Wood, 2003 #110}{Kao, 2004 #148}. Structural and functional homologs of Bre1 are found in other eukaryotes, but only in humans have any of th ...
... that Bre1 interacts with Rad6 and targets it to chromatin provides additional evidence that Bre1 is a bona fide E3 that directs Rad6 to its histone substrate{Wood, 2003 #110}{Kao, 2004 #148}. Structural and functional homologs of Bre1 are found in other eukaryotes, but only in humans have any of th ...
Hepatitis and HIV
... D. M. is a 38 y.o. man who has recently immigrated from India to join his wife who works as a nurse in the U.S. As part of the immigration process, he was tested for HIV and found to be positive. He has a history of multiple dental surgeries in India, but otherwise no medical problems. He denies a h ...
... D. M. is a 38 y.o. man who has recently immigrated from India to join his wife who works as a nurse in the U.S. As part of the immigration process, he was tested for HIV and found to be positive. He has a history of multiple dental surgeries in India, but otherwise no medical problems. He denies a h ...
Trachemys scripta elegans Red-Eared Turtle ( Fc)
... a hinge region encoded by a separate exon, which has been thought to be condensed into CH2 of IgY (15). However, our recent work on platypus Ig genes identified a new IgO-encoding gene and proved that the hinge region in IgG was independently formed at the 59 end of yCH2 and that yCH2 was lost durin ...
... a hinge region encoded by a separate exon, which has been thought to be condensed into CH2 of IgY (15). However, our recent work on platypus Ig genes identified a new IgO-encoding gene and proved that the hinge region in IgG was independently formed at the 59 end of yCH2 and that yCH2 was lost durin ...
PDF - Journal of Rare Disorders
... Each of our cells contains on an average 500 to 2,000 li le "power factories" called mitochondria that are responsible for supplying our energy needs. Approximately 1000 different proteins in mitochondria and defects in many such proteins can be characterized and described under the ...
... Each of our cells contains on an average 500 to 2,000 li le "power factories" called mitochondria that are responsible for supplying our energy needs. Approximately 1000 different proteins in mitochondria and defects in many such proteins can be characterized and described under the ...
Allele Mining Strategies: Principles and Utilisation for Blast
... the entire rice genome will be used to identify genes conferring important traits in the rice germplasm and to determine the function of unidentified genes in general. Molecular breeding approaches continue to be utilised in many countries to improve resistant and high-yielding commercial rice culti ...
... the entire rice genome will be used to identify genes conferring important traits in the rice germplasm and to determine the function of unidentified genes in general. Molecular breeding approaches continue to be utilised in many countries to improve resistant and high-yielding commercial rice culti ...
Evolution of the bilaterian germ line: lineage origin
... in the perinuclear cytoplasm associated with nuclear pores; (2) electron-dense cytoplasmic granules identifiable by transmission electron ...
... in the perinuclear cytoplasm associated with nuclear pores; (2) electron-dense cytoplasmic granules identifiable by transmission electron ...
Ocular Surface Disorders - Current Concepts and Management
... Topical autologous serum not only moistens the ocular surface, but also provides necessary tear proteins such as epidermal growth factor (EGF), vitamin A, transforming growth factor-B (TGF-B), fibronectin and other cytokines. The effect of EGF is primarily on epithelial wound healing whereas fibrone ...
... Topical autologous serum not only moistens the ocular surface, but also provides necessary tear proteins such as epidermal growth factor (EGF), vitamin A, transforming growth factor-B (TGF-B), fibronectin and other cytokines. The effect of EGF is primarily on epithelial wound healing whereas fibrone ...
(base) sequence of the genome might reflect biological information
... of chromosome II was enlarged to 990 nt (Figure 2(c), 648 ~ 1,638), or 1,584 nt (Figure 2(d), 54 ~ 1,638), respectively. That is, the base sequence of the complete ATP1 gene had self-similarity to the gene-position on chromosome II. Other genes of S. cerevisiae were highly homologous with the gene-p ...
... of chromosome II was enlarged to 990 nt (Figure 2(c), 648 ~ 1,638), or 1,584 nt (Figure 2(d), 54 ~ 1,638), respectively. That is, the base sequence of the complete ATP1 gene had self-similarity to the gene-position on chromosome II. Other genes of S. cerevisiae were highly homologous with the gene-p ...
Structural and Functional Studies of Insertion Element IS200
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
long program - Pan
... It is well documented that GRNs can evolve extensively through mutations to cis-regulatory modules. Transcription factor proteins that bind these cis-regulatory modules may also evolve to produce novelty. Coding changes, however, are considered to be more rare, because transcription factors are high ...
... It is well documented that GRNs can evolve extensively through mutations to cis-regulatory modules. Transcription factor proteins that bind these cis-regulatory modules may also evolve to produce novelty. Coding changes, however, are considered to be more rare, because transcription factors are high ...
SPT3 interacts with TFIID to allow normal transcription in
... function in vivo. To study further the sptlS-21 defect, extragenic suppressors of this mutation were isolated and analyzed. All of the extragenic suppressors of sptlS-21 are mutations in the previously identified SPT3 gene. Suppression of sptlS-21 by these spt3 mutations is allele-specific, suggesti ...
... function in vivo. To study further the sptlS-21 defect, extragenic suppressors of this mutation were isolated and analyzed. All of the extragenic suppressors of sptlS-21 are mutations in the previously identified SPT3 gene. Suppression of sptlS-21 by these spt3 mutations is allele-specific, suggesti ...
Final published version
... in a site-specific and oriented way in the ldhB promoter region results in high expression of the gene, and ultimately, this random event could restore a fully homolactic fermentation profile (20). In addition to the ldhB gene, two other genes, the ldhX and hicD (llmg_0475 in MG1363) genes, encoding ...
... in a site-specific and oriented way in the ldhB promoter region results in high expression of the gene, and ultimately, this random event could restore a fully homolactic fermentation profile (20). In addition to the ldhB gene, two other genes, the ldhX and hicD (llmg_0475 in MG1363) genes, encoding ...
Article On the Complexity of Chloroplast RNA
... the controls rescued with the WT gene (fig. 1). As might be expected from these results which showed that PsaA was present at normal levels, no changes were detectable in the growth rates of liquid cultures of the three trans-splicing mutants bypassed with the intron-less psaA, as compared with the ...
... the controls rescued with the WT gene (fig. 1). As might be expected from these results which showed that PsaA was present at normal levels, no changes were detectable in the growth rates of liquid cultures of the three trans-splicing mutants bypassed with the intron-less psaA, as compared with the ...
Spring 2016 Biology Item Release Scoring Guide
... Requires students to use subject-specific conceptual knowledge to interpret and explain events, phenomena, concepts and experiences using gradeappropriate scientific terminology, technological knowledge and mathematical knowledge. Communicate with clarity, focus and organization using rich, investig ...
... Requires students to use subject-specific conceptual knowledge to interpret and explain events, phenomena, concepts and experiences using gradeappropriate scientific terminology, technological knowledge and mathematical knowledge. Communicate with clarity, focus and organization using rich, investig ...
Paulina Vaitkienė A STUDY OF TUMOR SUPPRESSOR GENE
... suppressor gene O6-methylguanine DNA methyltransferase (MGMT), which encodes a DNA repair enzyme, sensitizes cancer cells to alkylating agents and is associated with a significantly improved outcome in GBM patients treated with radiotherapy and temozolomide (5). Recently, several microarray-based GB ...
... suppressor gene O6-methylguanine DNA methyltransferase (MGMT), which encodes a DNA repair enzyme, sensitizes cancer cells to alkylating agents and is associated with a significantly improved outcome in GBM patients treated with radiotherapy and temozolomide (5). Recently, several microarray-based GB ...
View PDF - OMICS International
... results showed 2 peaks of different size indicating a different numbers of CAG repeats between the 2 alleles on the two X chromosome; in non-digested sample, the 2 alleles had a different number of CAG repeats, while in the digested sample only 1 peak was found, suggesting a pattern of extremely ske ...
... results showed 2 peaks of different size indicating a different numbers of CAG repeats between the 2 alleles on the two X chromosome; in non-digested sample, the 2 alleles had a different number of CAG repeats, while in the digested sample only 1 peak was found, suggesting a pattern of extremely ske ...
DNA cytosine methylation in plant development
... Cytosine bases of the nuclear genome in higher plants are often extensively methylated. Cytosine methylation has been implicated in the silencing of both transposable elements (TEs) and endogenous genes, and loss of methylation may have severe functional consequences. The recent methylation profilin ...
... Cytosine bases of the nuclear genome in higher plants are often extensively methylated. Cytosine methylation has been implicated in the silencing of both transposable elements (TEs) and endogenous genes, and loss of methylation may have severe functional consequences. The recent methylation profilin ...
Journal of Bacteriology
... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...
... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...