SEGMENTAL VARIATION
... Importance of Copy Number Variants (CNVs) and Other Rearrangements in Health and Disease • Constitutional (germ-line) variants in hereditary conditions – Large and small copy number variants – Translocations and inversions: rarely cause a phenotype but may generate CNVs due to mis-pairing during me ...
... Importance of Copy Number Variants (CNVs) and Other Rearrangements in Health and Disease • Constitutional (germ-line) variants in hereditary conditions – Large and small copy number variants – Translocations and inversions: rarely cause a phenotype but may generate CNVs due to mis-pairing during me ...
i3017e02
... programmes will be an essential step in the initial phases of developing a national strategy and action plan for AnGR. Establishing linkages among institutions will be critical to maximizing efficiency in a cryoconservation programme. Collaboration with artificial insemination (AI) centres will be h ...
... programmes will be an essential step in the initial phases of developing a national strategy and action plan for AnGR. Establishing linkages among institutions will be critical to maximizing efficiency in a cryoconservation programme. Collaboration with artificial insemination (AI) centres will be h ...
Megaloblastic anemias
... If a patient with a severe megaloblastic anaemia is very ill and treatment must be started before vitamin B12 and red cell folate results are available, that treatment should always include both folic acid and vitamin B12. The use of folic acid alone in the presence of vitamin B12 deficiency may r ...
... If a patient with a severe megaloblastic anaemia is very ill and treatment must be started before vitamin B12 and red cell folate results are available, that treatment should always include both folic acid and vitamin B12. The use of folic acid alone in the presence of vitamin B12 deficiency may r ...
Interaction of Sesbania Mosaic Virus Movement Protein
... poly protein 2a, and ORF 2b for the RNA dependent RNA polymerase (RdRp) that is translated by a frame shift mechanism to yield poly protein 2ab. The 39- proximal ORF codes for the CP which is expressed via a sub genomic RNA [16]. The domain arrangement in poly protein 2a and 2ab was recently shown t ...
... poly protein 2a, and ORF 2b for the RNA dependent RNA polymerase (RdRp) that is translated by a frame shift mechanism to yield poly protein 2ab. The 39- proximal ORF codes for the CP which is expressed via a sub genomic RNA [16]. The domain arrangement in poly protein 2a and 2ab was recently shown t ...
MicroRNA: A novel class of master regulators of gene expression
... The challenges of studying microRNA are two-fold. First, the short nature (~22 nt) of microRNA sequences makes it difficult for traditional DNA-based analysis tools to achieve the required target sensitivity. Second, closely related microRNA family members differ by as little as one nucleotide, emph ...
... The challenges of studying microRNA are two-fold. First, the short nature (~22 nt) of microRNA sequences makes it difficult for traditional DNA-based analysis tools to achieve the required target sensitivity. Second, closely related microRNA family members differ by as little as one nucleotide, emph ...
38.1. Bone: Appendicular Skeleton, Trunk, Skull and Facial Bones
... High-grade conventional osteosarcoma. Osteosarcomas are characterized by complex DNA copy number alterations, with few recurrent abnormalities and a high level of genomic instability. To date, the search for common molecular therapeutic targets in osteosarcoma has been disappointing. However, the ge ...
... High-grade conventional osteosarcoma. Osteosarcomas are characterized by complex DNA copy number alterations, with few recurrent abnormalities and a high level of genomic instability. To date, the search for common molecular therapeutic targets in osteosarcoma has been disappointing. However, the ge ...
Gene duplications in prokaryotes can be
... Our paralog criterion was set to 75% identity between sequences. This is a fairly strict cut-off, as a more commonly used criterion is 30% sequence identity over more than 60% of the sequence length. By setting a relatively strict sequence identity cut-off, our analyses will focus on recently arisen ...
... Our paralog criterion was set to 75% identity between sequences. This is a fairly strict cut-off, as a more commonly used criterion is 30% sequence identity over more than 60% of the sequence length. By setting a relatively strict sequence identity cut-off, our analyses will focus on recently arisen ...
Chpt15_PosNegCntrl.doc
... For example, the lac operon encodes the enzymes needed for the uptake (lactose permease) and initial breakdown of lactose (the disaccharide -Dgalactosyl-1->4-D-glucose) into galactose and glucose (catalyzed by galactosidase). These monosaccharides are broken down to lactate (principally via glycol ...
... For example, the lac operon encodes the enzymes needed for the uptake (lactose permease) and initial breakdown of lactose (the disaccharide -Dgalactosyl-1->4-D-glucose) into galactose and glucose (catalyzed by galactosidase). These monosaccharides are broken down to lactate (principally via glycol ...
ch 5 presentation
... • Lipids are the one class of large biological molecules that do not form polymers • The unifying feature of lipids is having little or no affinity for water • Lipids are hydrophobic because they consist mostly of hydrocarbons, which form nonpolar covalent bonds • The most biologically important lip ...
... • Lipids are the one class of large biological molecules that do not form polymers • The unifying feature of lipids is having little or no affinity for water • Lipids are hydrophobic because they consist mostly of hydrocarbons, which form nonpolar covalent bonds • The most biologically important lip ...
Twin methodology in epigenetic studies
... the full ACE model can be compared with its nested models including the AE model (dropping the C component), the CE model (dropping the A component) and E model (dropping the A and C components). This enables selection of the best fitting and most parsimonious model for a given set of data. Instead ...
... the full ACE model can be compared with its nested models including the AE model (dropping the C component), the CE model (dropping the A component) and E model (dropping the A and C components). This enables selection of the best fitting and most parsimonious model for a given set of data. Instead ...
Analyses of complete nucleotide sequence of Iranian isolate of
... 2004; Masumi and Izadpanah 1998; Seifers et al. 2000; Salomon and Seifers 2004; Zare et al. 2005; 2006). Most of these viruses can infect maize. They all have a single stranded RNA genome of approximately 9500 nucleotides, encoding a single large polyprotein that is proteolytically processed by the ...
... 2004; Masumi and Izadpanah 1998; Seifers et al. 2000; Salomon and Seifers 2004; Zare et al. 2005; 2006). Most of these viruses can infect maize. They all have a single stranded RNA genome of approximately 9500 nucleotides, encoding a single large polyprotein that is proteolytically processed by the ...
Coupling of zygotic transcription to mitotic control at the Drosophila
... Xuemin Lu1, Jennifer M. Li2, Olivier Elemento3, Saeed Tavazoie3 and Eric F. Wieschaus1,4,* One of the most prominent features at the mid-blastula transition (MBT) observed in most embryos is a pause in cell cycle regulated by the nucleocytoplasmic (N/C) ratio. By using chromosome rearrangements to m ...
... Xuemin Lu1, Jennifer M. Li2, Olivier Elemento3, Saeed Tavazoie3 and Eric F. Wieschaus1,4,* One of the most prominent features at the mid-blastula transition (MBT) observed in most embryos is a pause in cell cycle regulated by the nucleocytoplasmic (N/C) ratio. By using chromosome rearrangements to m ...
current micro 40/5 - Bashan Foundation
... Reverse transcription (RT) and PCR. Prior to RT, 2 µg RNA was digested with 2 U DNase (deoxyribonuclease I, amplification grade, Gibco/BRL) in a volume of 20 µl (15 min, 25°C) with the buffer supplied by the manufacturer. The digestion was stopped by adding 2 µl 25 mM EDTA and incubating (10 min, 65 ...
... Reverse transcription (RT) and PCR. Prior to RT, 2 µg RNA was digested with 2 U DNase (deoxyribonuclease I, amplification grade, Gibco/BRL) in a volume of 20 µl (15 min, 25°C) with the buffer supplied by the manufacturer. The digestion was stopped by adding 2 µl 25 mM EDTA and incubating (10 min, 65 ...
Inheritance Lecture Notes - Instruction.greenriver.edu
... of the ligand-binding domain [maximal binding capacity, 38.2 fmol/mg protein (normal); Kd, 0.21 nmol/L; normal range, 0.03–0.13 nmol/L]. In trans-activation assays, the mutant 712F-AR showed considerable deficiency at low concentrations of testosterone (0.01–0.1 nmol/L) or dihydrotestosterone (0.01 ...
... of the ligand-binding domain [maximal binding capacity, 38.2 fmol/mg protein (normal); Kd, 0.21 nmol/L; normal range, 0.03–0.13 nmol/L]. In trans-activation assays, the mutant 712F-AR showed considerable deficiency at low concentrations of testosterone (0.01–0.1 nmol/L) or dihydrotestosterone (0.01 ...
Translating Stem Cell Research to Cardiac Disease Therapies
... Cardiology, University of Miami, Miller School of Medicine, Miami, Florida; zInternational Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and the xCedars-Sinai Heart Institute, Los Angeles, California. Dr. Rosen has received support ...
... Cardiology, University of Miami, Miller School of Medicine, Miami, Florida; zInternational Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London, London, United Kingdom; and the xCedars-Sinai Heart Institute, Los Angeles, California. Dr. Rosen has received support ...
Prokaryote Gene Expression Section 1 Overview of RNA
... RNA and protein synthesis are coupled processes in prokaryotes As soon as the 5’ end of the mRNA is biosynthesised it is available for translation Ribosomes bind, and start protein synthesis Degradation of the mRNA starts from the 5’ end through exoRNAase action The 5’ end can be degraded before the ...
... RNA and protein synthesis are coupled processes in prokaryotes As soon as the 5’ end of the mRNA is biosynthesised it is available for translation Ribosomes bind, and start protein synthesis Degradation of the mRNA starts from the 5’ end through exoRNAase action The 5’ end can be degraded before the ...
PDF - The Journal of General Physiology
... three different dates corresponding to 0, 40, and 50 per cent of the incorporated p3~ decayed. A total of nine different emulsions was counted; the average star size extended from 7.4 to 15.4 rays per star. The average of these determinations for the average number of p~2 atoms per phage particle, N ...
... three different dates corresponding to 0, 40, and 50 per cent of the incorporated p3~ decayed. A total of nine different emulsions was counted; the average star size extended from 7.4 to 15.4 rays per star. The average of these determinations for the average number of p~2 atoms per phage particle, N ...
UP-CPMT - 2007 Paper-1
... 3) nephron 4) both (1) and (2) 41. Regeneration in Hydra will be faster if it is cut off from 1) tentacles 2) hypostome 3) base 4) all of these 42. First mammal occur in which era-period? ...
... 3) nephron 4) both (1) and (2) 41. Regeneration in Hydra will be faster if it is cut off from 1) tentacles 2) hypostome 3) base 4) all of these 42. First mammal occur in which era-period? ...
Proc. Natl. Acad. Sci. USA 96, 4718-4723.
... presence of conserved EF-hand motifs in the predicted protein sequence of AtCBL suggests that it may function as a Ca21binding protein. To examine this possibility, we expressed the recombinant AtCBL1 protein as a GST fusion in Escherichia coli. Two approaches were used to confirm that the recombina ...
... presence of conserved EF-hand motifs in the predicted protein sequence of AtCBL suggests that it may function as a Ca21binding protein. To examine this possibility, we expressed the recombinant AtCBL1 protein as a GST fusion in Escherichia coli. Two approaches were used to confirm that the recombina ...
1 Total out of 100
... Your mom emails you and asks you to explain this news article to her. She is an astute individual and a supporter of government-sponsored research, but is a bit mystified about the relationship between fly and human alcohol consumption and wonders how the implied significance of the fly research can ...
... Your mom emails you and asks you to explain this news article to her. She is an astute individual and a supporter of government-sponsored research, but is a bit mystified about the relationship between fly and human alcohol consumption and wonders how the implied significance of the fly research can ...
Sathgudi Sweet orange
... 2. The complete genome of CMBVSON consisted of 7558 nucleotide containing for 6 open reading frames (ORFs). High variability (87.4% to 96%) observed in ORF 4 and 5 infecting sathgudi sweet orange, rangpur lime acid lime and pummelo. 3. The intergenic region (non coding region) has 731 nucleotide. In ...
... 2. The complete genome of CMBVSON consisted of 7558 nucleotide containing for 6 open reading frames (ORFs). High variability (87.4% to 96%) observed in ORF 4 and 5 infecting sathgudi sweet orange, rangpur lime acid lime and pummelo. 3. The intergenic region (non coding region) has 731 nucleotide. In ...