Clinical Microbiology Reviews
... The true value of an MIC is as a measuring tool that generates values to which other parameters, such as PD end points and clinical outcomes, can be reliably compared. This requires that MICs have a reasonable level of reproducibility, a subject that has not received a great deal of attention over t ...
... The true value of an MIC is as a measuring tool that generates values to which other parameters, such as PD end points and clinical outcomes, can be reliably compared. This requires that MICs have a reasonable level of reproducibility, a subject that has not received a great deal of attention over t ...
Chance and Necessity in Arthur Peacocke`s Scientific Work
... and communion of the whole of creation. At the very root of his subsequent deep thoughts on the nature of the universe and laws of creation, lay these first experiments. For somebody else, those could have been just data, but for Peacocke they germinated into something more metaphysical. The results ...
... and communion of the whole of creation. At the very root of his subsequent deep thoughts on the nature of the universe and laws of creation, lay these first experiments. For somebody else, those could have been just data, but for Peacocke they germinated into something more metaphysical. The results ...
Role of mimivirus collagen in rheumatoid arthritis
... widespread evolutionary and biological importance. The giant mimivirus is an amoebaassociated virus that replicates in the ubiquitously present amoeba Acanthamoeba polyphaga. Sequence analysis revealed that mimivirus harbours a linear double stranded DNA genome of ~1.2 Mbp making mimivirus the third ...
... widespread evolutionary and biological importance. The giant mimivirus is an amoebaassociated virus that replicates in the ubiquitously present amoeba Acanthamoeba polyphaga. Sequence analysis revealed that mimivirus harbours a linear double stranded DNA genome of ~1.2 Mbp making mimivirus the third ...
DOCTORAL THESIS
... 2. – EDEN To understand and modify the secondary cell walls of plants the project group Enzyme Discovery in Hybrid Aspen for Fiber Engineering (EDEN) was founded composed of nine laboratories in seven countries with funding from the European Commission. The main target of EDEN´s research is to genet ...
... 2. – EDEN To understand and modify the secondary cell walls of plants the project group Enzyme Discovery in Hybrid Aspen for Fiber Engineering (EDEN) was founded composed of nine laboratories in seven countries with funding from the European Commission. The main target of EDEN´s research is to genet ...
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... hybridization. Expression was found not only in the central nervous system, as was expected from the expression pattern of the endogenous Ndn gene, but also to be comparatively widespread, suggesting that the promoter region did not contain all of the regulatory control sequences present in the endo ...
... hybridization. Expression was found not only in the central nervous system, as was expected from the expression pattern of the endogenous Ndn gene, but also to be comparatively widespread, suggesting that the promoter region did not contain all of the regulatory control sequences present in the endo ...
Sickle Cell Disease - The Center for Children with Special Needs
... overwhelmed by schoolwork, and they may not know how to ask for assistance. They may not be able to catch up on missed assignments and may not feel a sense of belonging in the classroom. This can lead to intense feelings regarding relationships at school. In most cases the child will not be able to ...
... overwhelmed by schoolwork, and they may not know how to ask for assistance. They may not be able to catch up on missed assignments and may not feel a sense of belonging in the classroom. This can lead to intense feelings regarding relationships at school. In most cases the child will not be able to ...
The Critical Elements of Care (CEC) considers care issues across the life span of the child and is intended to educate and support those caring for a child with sickle cell disease.
... overwhelmed by schoolwork, and they may not know how to ask for assistance. They may not be able to catch up on missed assignments and may not feel a sense of belonging in the classroom. This can lead to intense feelings regarding relationships at school. In most cases the child will not be able to ...
... overwhelmed by schoolwork, and they may not know how to ask for assistance. They may not be able to catch up on missed assignments and may not feel a sense of belonging in the classroom. This can lead to intense feelings regarding relationships at school. In most cases the child will not be able to ...
`Candidatus Phytoplasma mali`, `Candidatus Phytoplasma pyri` and
... group, 2004). According to these recommendations, ‘a phytoplasma can be described as a novel ‘Candidatus Phytoplasma’ species if its 16S rDNA sequence has <97?5 % similarity to that of any previously described ‘Candidatus Phytoplasma’ species’. In cases where phytoplasmas share ¢97?5 % 16S rDNA sequ ...
... group, 2004). According to these recommendations, ‘a phytoplasma can be described as a novel ‘Candidatus Phytoplasma’ species if its 16S rDNA sequence has <97?5 % similarity to that of any previously described ‘Candidatus Phytoplasma’ species’. In cases where phytoplasmas share ¢97?5 % 16S rDNA sequ ...
Nonsensemediated decay of glutathione peroxidase 1 mRNA in the
... (Moriarty et al., 1998). These ®ndings indicate that halflife studies comparing the consequences of converting the UGA Sec codon to either UAA or UGC will determine whether the NMD of GPx1 mRNA is restricted to newly exported mRNA or characteristic of steady-state mRNA. An intron-less GPx1 gene fail ...
... (Moriarty et al., 1998). These ®ndings indicate that halflife studies comparing the consequences of converting the UGA Sec codon to either UAA or UGC will determine whether the NMD of GPx1 mRNA is restricted to newly exported mRNA or characteristic of steady-state mRNA. An intron-less GPx1 gene fail ...
Ebola haemorrhagic fever
... products are detectable, indicating diffuse intravascular coagulopathy. In a later stage, secondary bacterial infection might lead to raised counts of white blood cells.1,37–39 Patients with fatal disease develop clinical signs early during infection and die typically between day 6 and 16 with hypovo ...
... products are detectable, indicating diffuse intravascular coagulopathy. In a later stage, secondary bacterial infection might lead to raised counts of white blood cells.1,37–39 Patients with fatal disease develop clinical signs early during infection and die typically between day 6 and 16 with hypovo ...
Vernalization Gene Architecture as a Predictor of Growth Habit in
... facultative forms can be planted in the fall or spring. Growth habit is important because it determines the range of adaptation. Winter and fall-sown facultative varieties generally yield more than spring-planted forms, provided that they have sufficient winter hardiness. However, a lack of winter ...
... facultative forms can be planted in the fall or spring. Growth habit is important because it determines the range of adaptation. Winter and fall-sown facultative varieties generally yield more than spring-planted forms, provided that they have sufficient winter hardiness. However, a lack of winter ...
hhmi resource for new ap bio curriculum
... field of Biology (the breadth) with the depth of understanding of fundamental topics required of the students. The new course shifts from focusing on content coverage to a focus on enduring conceptual understandings and the supporting content. For the purpose of this teacher guide, the main foci wil ...
... field of Biology (the breadth) with the depth of understanding of fundamental topics required of the students. The new course shifts from focusing on content coverage to a focus on enduring conceptual understandings and the supporting content. For the purpose of this teacher guide, the main foci wil ...
Neisseria meningitidis: an overview of the carriage state
... During periods of endemic disease, about 10 % of the general population harbour Neisseria meningitidis in the nasopharynx. Since N. meningitidis is a strict human pathogen and most patients have not been in contact with other cases, asymptomatic carriers are presumably the major source of the pathog ...
... During periods of endemic disease, about 10 % of the general population harbour Neisseria meningitidis in the nasopharynx. Since N. meningitidis is a strict human pathogen and most patients have not been in contact with other cases, asymptomatic carriers are presumably the major source of the pathog ...
A novel role for the floral homeotic gene APETALA2
... valves and replum, respectively. In ful rpl double mutants, the valve margin identity genes become ectopically expressed, and, as a result, the entire outer surface of the ovary takes on valve margin identity. We carried out a genetic screen in this sensitized genetic background and identified a sup ...
... valves and replum, respectively. In ful rpl double mutants, the valve margin identity genes become ectopically expressed, and, as a result, the entire outer surface of the ovary takes on valve margin identity. We carried out a genetic screen in this sensitized genetic background and identified a sup ...
Leukaemia Section 3q rearrangements in myeloid malignancies Atlas of Genetics and Cytogenetics
... Recently we demonstrated EVI1 involvement in other recurrent rearrangements such as: - t(2;3)(p13-p23;q26) - t(3;6)(q26;q25) - t(3;13)(q26;q14) - t(3;17)(q26;q22) In addition, EVI1 is involved in more rare rearrangements such as inv(3)(p12q26) inv(3)(q23q26) - t(3;3)(p24;q26) - t(3;5)(q26;q34) - t(3 ...
... Recently we demonstrated EVI1 involvement in other recurrent rearrangements such as: - t(2;3)(p13-p23;q26) - t(3;6)(q26;q25) - t(3;13)(q26;q14) - t(3;17)(q26;q22) In addition, EVI1 is involved in more rare rearrangements such as inv(3)(p12q26) inv(3)(q23q26) - t(3;3)(p24;q26) - t(3;5)(q26;q34) - t(3 ...
RNA Editing, ADAR1, and the Innate Immune Response
... ADAR1 was originally thought to be the enzyme responsible for GluR-B mRNA editing [41,42] and through this function significantly affect neurological functions [43–45]. However, this important editing was subsequently attributed to ADAR2 [24]. ADAR1 indeed participates in the editing of many other s ...
... ADAR1 was originally thought to be the enzyme responsible for GluR-B mRNA editing [41,42] and through this function significantly affect neurological functions [43–45]. However, this important editing was subsequently attributed to ADAR2 [24]. ADAR1 indeed participates in the editing of many other s ...
Molecular Cloning of Dog Mast Cell Tryptase and a Related Protease
... (Gruber et al., 1988). These latter findings suggest that tryptase may have a proinflammatory role and may act locally with degranulated mast cell heparin as an anticoagulant. Mast cell tryptase differs markedly from other serine proteases in many of its biochemical features. It has two or more subu ...
... (Gruber et al., 1988). These latter findings suggest that tryptase may have a proinflammatory role and may act locally with degranulated mast cell heparin as an anticoagulant. Mast cell tryptase differs markedly from other serine proteases in many of its biochemical features. It has two or more subu ...
Hemolytic Anemias
... synthesis of β chains – compensatory increase in γ and δ chains – increased levels of fetal Hb (α2γ2) and Hb A2 (α2δ2) The excess α chain are toxic to RBC -markedly reduced life span of RBC (= hemolytic anemia) Tetramers of α chains have very high O2 affinity – poor delivery of oxygen to tissues ...
... synthesis of β chains – compensatory increase in γ and δ chains – increased levels of fetal Hb (α2γ2) and Hb A2 (α2δ2) The excess α chain are toxic to RBC -markedly reduced life span of RBC (= hemolytic anemia) Tetramers of α chains have very high O2 affinity – poor delivery of oxygen to tissues ...
Age-related macular degeneration: a perspective on genetic studies
... predisposed to AMD but these results have been disputed in later studies.14,15 The role of ABCA4 remains uncertain in AMD and the possibility that this gene causes a small number of AMD cases cannot be excluded. The protein bestrophin and its gene mutation is responsible for vitelliform macular dyst ...
... predisposed to AMD but these results have been disputed in later studies.14,15 The role of ABCA4 remains uncertain in AMD and the possibility that this gene causes a small number of AMD cases cannot be excluded. The protein bestrophin and its gene mutation is responsible for vitelliform macular dyst ...
Product description P003-D1 MLH1-MSH2-v01 - MRC
... containing MLH1 or MSH2 exon deletions or amplifications: http://www.nibsc.org/documents/ifu/11-218xxx.pdf. As an alternative, an artificial positive duplication DNA sample for MLH1 and MSH2 (product name SD027) can be ordered from MRC-Holland. This FOR RESEARCH USE ONLY SD027 DNA will show a duplic ...
... containing MLH1 or MSH2 exon deletions or amplifications: http://www.nibsc.org/documents/ifu/11-218xxx.pdf. As an alternative, an artificial positive duplication DNA sample for MLH1 and MSH2 (product name SD027) can be ordered from MRC-Holland. This FOR RESEARCH USE ONLY SD027 DNA will show a duplic ...
The development of apical embryonic pattern in Arabidopsis
... must derive from the EPR. In agreement with this, the bases of of embryogenesis, expression has spread and is found in a the cotyledons meet along a region that is three to four cells in continuous band between the presumptive cotyledons (Fig. diameter in the wild-type – approximately the same numbe ...
... must derive from the EPR. In agreement with this, the bases of of embryogenesis, expression has spread and is found in a the cotyledons meet along a region that is three to four cells in continuous band between the presumptive cotyledons (Fig. diameter in the wild-type – approximately the same numbe ...
Thesis_Lars Brichta_final
... All past and present members of the “SMA group” for being good workmates, especially Irmgard Hölker for contributing with skillful technical assistance (!), Claudia Helmken for reading the draft and for sending her unique and refreshing weekly e-mails maintaining a consistent atmosphere of good humo ...
... All past and present members of the “SMA group” for being good workmates, especially Irmgard Hölker for contributing with skillful technical assistance (!), Claudia Helmken for reading the draft and for sending her unique and refreshing weekly e-mails maintaining a consistent atmosphere of good humo ...
Genetics of Hemophilia
... arranged in sets of three, triplets, each set called a codon because it is a code. Given that there are four nucleotides, and each could be first, second or third within a codon (reading in only one direction), there are 64 possible codons. Of these possibilities, 61 call for specific amino acids an ...
... arranged in sets of three, triplets, each set called a codon because it is a code. Given that there are four nucleotides, and each could be first, second or third within a codon (reading in only one direction), there are 64 possible codons. Of these possibilities, 61 call for specific amino acids an ...