Virulence factors of Salmonella enterica serovar Enteritidis
... Bacterial penetration of the intestinal mucosa is often an important step in the establishment of an infection as it enables the microorganisms to pass the epithelial barrier. In mice, serovar Typhimurium has been demonstrated to invade the mucosal tissue rapidly. Both enterocytes and M cells can be ...
... Bacterial penetration of the intestinal mucosa is often an important step in the establishment of an infection as it enables the microorganisms to pass the epithelial barrier. In mice, serovar Typhimurium has been demonstrated to invade the mucosal tissue rapidly. Both enterocytes and M cells can be ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... reaction (PCR), and then digestion of the PCR products by restriction enzymes (RFLP) for both genes was performed. As regards GSTP1, the carriers of Val (G) allele were significantly more frequent among preeclampsia patients when compared to the control group (45.95% Vs. 19%, X2=10.40, OR=2.418, 95% ...
... reaction (PCR), and then digestion of the PCR products by restriction enzymes (RFLP) for both genes was performed. As regards GSTP1, the carriers of Val (G) allele were significantly more frequent among preeclampsia patients when compared to the control group (45.95% Vs. 19%, X2=10.40, OR=2.418, 95% ...
Polymeric nanoreactors for use in enzyme replacement therapy
... Nuclear DNA (nDNA) relies more on the de novo salvage pathway and is not affected by increased thymidine levels. ...
... Nuclear DNA (nDNA) relies more on the de novo salvage pathway and is not affected by increased thymidine levels. ...
Dickkopf1 Is Required for Embryonic Head Induction
... inhibit the Spemann organizer during embryonic head induction. That this pathway is capable of antagonizing the head organizer is suggested by the overexpression of Wnts during gastrulation, which leads to microcephaly in Xenopus (Christian and Moon, 1993; McGrew et al., 1997) and possibly in mouse ...
... inhibit the Spemann organizer during embryonic head induction. That this pathway is capable of antagonizing the head organizer is suggested by the overexpression of Wnts during gastrulation, which leads to microcephaly in Xenopus (Christian and Moon, 1993; McGrew et al., 1997) and possibly in mouse ...
PCR Clean-up Kit / 96-well PCR Clean
... cosmid DNA (per well) from up to 1.3 ml of bacterial culture. This method is based on a modified alkaline lysis of the bacteria in combination with the selective binding of the plasmid DNA to a special silica membrane. The purified plasmid or cosmid DNA is free from protein, genomic DNA and RNA and ...
... cosmid DNA (per well) from up to 1.3 ml of bacterial culture. This method is based on a modified alkaline lysis of the bacteria in combination with the selective binding of the plasmid DNA to a special silica membrane. The purified plasmid or cosmid DNA is free from protein, genomic DNA and RNA and ...
Aalborg Universitet Detection, identification and quantification of microorganisms in selected infections
... the realization that the culture-dependent methods employed for decades to identify the causative pathogens may have some insufficiencies. The purpose of this PhD study has been to evaluate if alternative methods to culture-dependent techniques could be used to investigate the microbial communities ...
... the realization that the culture-dependent methods employed for decades to identify the causative pathogens may have some insufficiencies. The purpose of this PhD study has been to evaluate if alternative methods to culture-dependent techniques could be used to investigate the microbial communities ...
Cloning and sequencing of the kedarcidin biosynthetic
... (ii) the (R)-2-aza-3-chloro-b-tyrosine moiety that has not been seen in any other natural product, (iii) a deceivingly simple isopropoxy group at the 2-naphthonate moiety, the biosynthesis of which has little literature precedence, and (iv) the peripheral moieties are appended to the enediyne core w ...
... (ii) the (R)-2-aza-3-chloro-b-tyrosine moiety that has not been seen in any other natural product, (iii) a deceivingly simple isopropoxy group at the 2-naphthonate moiety, the biosynthesis of which has little literature precedence, and (iv) the peripheral moieties are appended to the enediyne core w ...
Are there errors in glycogen biosynthesis and is laforin a repair
... question. The idea of an “error” requires that there is a “correct” outcome. Much discussion of catalytic errors has addressed the biosynthesis of information-rich biopolymers, like DNA [10], RNA [11] and proteins [12], for which a “correct” product can be defined. Errors occur when an incongruent b ...
... question. The idea of an “error” requires that there is a “correct” outcome. Much discussion of catalytic errors has addressed the biosynthesis of information-rich biopolymers, like DNA [10], RNA [11] and proteins [12], for which a “correct” product can be defined. Errors occur when an incongruent b ...
chromosomal
... interstitial deletion Caused by very small deletion on the long arm of chromosome 7. Deletion include elastin gene which code a protein that gives the blood vessels the stretchiness The lack of the elastin protein, people with Williams syndrome have disorder of circulatory system ...
... interstitial deletion Caused by very small deletion on the long arm of chromosome 7. Deletion include elastin gene which code a protein that gives the blood vessels the stretchiness The lack of the elastin protein, people with Williams syndrome have disorder of circulatory system ...
Mutations at the Darkener of apricot Locus Modulate Transcript
... at wa and w5Ps5,since white alleles with point mutations do not respond (RABINOW and BIRCHLER 1989). Doa acts upon wa as an inverse function ofits own dosage, i.e., is lightened by additional copies of wild-type Doa. Conversely, WJfis5 is directly affected by Doa, addition of wild-type copies produc ...
... at wa and w5Ps5,since white alleles with point mutations do not respond (RABINOW and BIRCHLER 1989). Doa acts upon wa as an inverse function ofits own dosage, i.e., is lightened by additional copies of wild-type Doa. Conversely, WJfis5 is directly affected by Doa, addition of wild-type copies produc ...
Genetic Codes with No Dedicated Stop Codon: Context
... While the genetic code is classically taught as being unambiguous, and indeed may largely be so, we now know this is an oversimplification. Since the original discovery of the standard genetic code, alternative translational interpretations of codons have been found, most notably in the use of the U ...
... While the genetic code is classically taught as being unambiguous, and indeed may largely be so, we now know this is an oversimplification. Since the original discovery of the standard genetic code, alternative translational interpretations of codons have been found, most notably in the use of the U ...
A Point Mutation in Transthyretin Increases Affinity for Thyroxine and
... overlap between the two groups. Free T4 by equilibrium dialysis and by a two-step direct free T4 assay was normal in all affected subjects. There was no significant difference in serum T3 levels between affected (135±21 ng/dl) and unaffected subjects (127±22 ng/dl). The latter finding is not unexpec ...
... overlap between the two groups. Free T4 by equilibrium dialysis and by a two-step direct free T4 assay was normal in all affected subjects. There was no significant difference in serum T3 levels between affected (135±21 ng/dl) and unaffected subjects (127±22 ng/dl). The latter finding is not unexpec ...
An unusual N-terminal deletion of the laminin a3a isoform leads to
... Laryngo-onycho-cutaneous (LOC or Shabbir) syndrome (OMIM 245660) is an autosomal recessive epithelial disorder confined to the Punjabi Muslim population. The condition is characterized by cutaneous erosions, nail dystrophy and exuberant vascular granulation tissue in certain epithelia, especially con ...
... Laryngo-onycho-cutaneous (LOC or Shabbir) syndrome (OMIM 245660) is an autosomal recessive epithelial disorder confined to the Punjabi Muslim population. The condition is characterized by cutaneous erosions, nail dystrophy and exuberant vascular granulation tissue in certain epithelia, especially con ...
Review Article Antimicrobial Peptides: Their Role as Infection-Selective Tracers for Molecular Imaging
... of leukocytes is considered the “gold standard” for infection imaging by PET. Unfortunately this process is very laborious and time-consuming and requires the handling of blood products [3–5]. Alternatively, indirectly labeled leukocytes can be achieved using radiolabeled molecules, such as chemotac ...
... of leukocytes is considered the “gold standard” for infection imaging by PET. Unfortunately this process is very laborious and time-consuming and requires the handling of blood products [3–5]. Alternatively, indirectly labeled leukocytes can be achieved using radiolabeled molecules, such as chemotac ...
SALSA MLPA probemix P018-F1 SHOX - MRC
... within the PAR1 region (pseudoautosomal region 1) which covers the 3000 kb of the X and Y chromosomes next to the p-telomere. This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are pres ...
... within the PAR1 region (pseudoautosomal region 1) which covers the 3000 kb of the X and Y chromosomes next to the p-telomere. This P018-F1 SHOX probemix contains probes for each exon of the human SHOX gene, as well as a probe just before the SHOX promoter region. In addition, several probes are pres ...
Molecular mechanics of the interactions of spermine with DNA: DNA
... of conformations, however, and there are a variety of distances and positions between the primary and secondary amino groups. Energetics of Spermine/DNA Complexes. Numerical results for spemune/DNA complexes are summarized in Tables I-IV. Because energies for each DNA sequence will be different, abs ...
... of conformations, however, and there are a variety of distances and positions between the primary and secondary amino groups. Energetics of Spermine/DNA Complexes. Numerical results for spemune/DNA complexes are summarized in Tables I-IV. Because energies for each DNA sequence will be different, abs ...
Matricellular Protein Cyr61 Bridges Lysophosphatidic Acid and
... temporal and spatial expression in SMCs. We observed specific and dramatic induction of Cyr61 expression stimulated by LPA in vascular SMCs. We further explored the role of Cyr61 in LPA-induced SMC migration and related molecular mechanisms. LPA elicits cellular responses mainly via its cognate G-pr ...
... temporal and spatial expression in SMCs. We observed specific and dramatic induction of Cyr61 expression stimulated by LPA in vascular SMCs. We further explored the role of Cyr61 in LPA-induced SMC migration and related molecular mechanisms. LPA elicits cellular responses mainly via its cognate G-pr ...
PTENgene and carcinoma of the endometrium
... 1992; Burke et al, 1996; Prat, 1996). Many patients have an increased capacity for converting androstenedione (of adrenal origin) to estrone in the body fat and hence the association with obesity (Fox, 1992; Prat, 1996). Interestingly, risk factors such as obesity, menstrual irregularities and nulli ...
... 1992; Burke et al, 1996; Prat, 1996). Many patients have an increased capacity for converting androstenedione (of adrenal origin) to estrone in the body fat and hence the association with obesity (Fox, 1992; Prat, 1996). Interestingly, risk factors such as obesity, menstrual irregularities and nulli ...
Nucleic acid vaccines against rickettsial diseases and methods of use
... have been developed against certain rickettsial diseases, for example against R. prowazekii and R. rickettsii. HoWever, these vaccines have major problems or disadvantages, including undesirable toxic reactions, difficulty in standardiZation, and expense (WoodWard, T. [1981] “Rick ...
... have been developed against certain rickettsial diseases, for example against R. prowazekii and R. rickettsii. HoWever, these vaccines have major problems or disadvantages, including undesirable toxic reactions, difficulty in standardiZation, and expense (WoodWard, T. [1981] “Rick ...
genomebiology.com
... revealed that TEs are less likely to be fixed within transcribed regions relative to orthologous regions in human and mouse [16]. In G. gallus, D. rerio and C. intestinalis, 33.2%, 47.3% and 39.4% of TEs reside within introns, respectively, whereas in the human genome, approximately 60% of TEs resid ...
... revealed that TEs are less likely to be fixed within transcribed regions relative to orthologous regions in human and mouse [16]. In G. gallus, D. rerio and C. intestinalis, 33.2%, 47.3% and 39.4% of TEs reside within introns, respectively, whereas in the human genome, approximately 60% of TEs resid ...
The Myriad case (Association for Molecular Pathology v
... • Native BRCA1/2 resides on chromosomes 17/13 part of millions of nucleotides • Isolated BRCA1/2 – exons only covering as few as 15 to about 10000 nucleotides not found in nature © 2011 Connolly Bove Lodge & Hutz LLP • Focus is on structure Myriad Slip Op. at 42 © 2011 Connolly Bove Lodge & Hutz ...
... • Native BRCA1/2 resides on chromosomes 17/13 part of millions of nucleotides • Isolated BRCA1/2 – exons only covering as few as 15 to about 10000 nucleotides not found in nature © 2011 Connolly Bove Lodge & Hutz LLP • Focus is on structure Myriad Slip Op. at 42 © 2011 Connolly Bove Lodge & Hutz ...
Rapamycin increases mitochondrial efficiency by mtDNA
... activity, decreases H2O2 production and generates distinct shifts in the metabolite profiles ...
... activity, decreases H2O2 production and generates distinct shifts in the metabolite profiles ...