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... - Expressed primarily on Ag-presenting cells (macrophages, dendritic cells, and B cells), where they present processed ...
... - Expressed primarily on Ag-presenting cells (macrophages, dendritic cells, and B cells), where they present processed ...
Analysis of the histone H3 gene family in Arabidopsis and
... Histones are major components of chromatin, the protein–DNA complex involved in DNA packaging and transcriptional regulation. Histone genes have been extensively investigated at the genome level in animal systems and have been classified as replication dependent, replication independent or tissue sp ...
... Histones are major components of chromatin, the protein–DNA complex involved in DNA packaging and transcriptional regulation. Histone genes have been extensively investigated at the genome level in animal systems and have been classified as replication dependent, replication independent or tissue sp ...
Tracing the origin of our species through palaeogenomics
... length. These sequences had then to be mapped to the phylogenetically closest genome available, in this case the one of present-day humans, since a de novo assemblage of an ancient genome based on these short molecules is not possible. The sequences may contain mistakes due to the damages that occur ...
... length. These sequences had then to be mapped to the phylogenetically closest genome available, in this case the one of present-day humans, since a de novo assemblage of an ancient genome based on these short molecules is not possible. The sequences may contain mistakes due to the damages that occur ...
Functions of DNA methylation: islands, start sites, gene bodies and
... there is abundant evidence that methylated CGIs at TSSs are associated with some silent genes, the timing of de novo methylation with respect to gene silencing is now beginning to be elucidated. The function of DNA methylation is intrinsically linked to the mechanisms for establishing, maintaining a ...
... there is abundant evidence that methylated CGIs at TSSs are associated with some silent genes, the timing of de novo methylation with respect to gene silencing is now beginning to be elucidated. The function of DNA methylation is intrinsically linked to the mechanisms for establishing, maintaining a ...
... hydrophobic agents, particularly for xenobiotics such as benzo(a)pyrene. It has also been shown to regulate cell-volume activated chloride channels. Pgp 170 could, therefore, be of particular importance in cellular mechanisms of defence in the airways and in the control of mucus layer composition. F ...
A new polymerase chain reaction/restriction fragment length
... second enzyme has no restriction site for VK210 (Fig. 2). Other fragments below 38 bp, not considered for variant determination, were also formed after the RFLP procedure. 4. Discussion Malaria is one of the most prevalent severe infectious diseases in tropical and subtropical regions worldwide. Bec ...
... second enzyme has no restriction site for VK210 (Fig. 2). Other fragments below 38 bp, not considered for variant determination, were also formed after the RFLP procedure. 4. Discussion Malaria is one of the most prevalent severe infectious diseases in tropical and subtropical regions worldwide. Bec ...
medically important viruses
... Dissemination occurs in patients with depressed cell-mediated immunity. Laboratory Diagnosis: Virus causes cytopathic effect (CPE) in cell culture. ...
... Dissemination occurs in patients with depressed cell-mediated immunity. Laboratory Diagnosis: Virus causes cytopathic effect (CPE) in cell culture. ...
Analysis and nucleotide sequence of an origin of DNA replication in
... in the pBR322 vector portion, pWHI266 was partially digested with $au3A, ligated with the BamHl cleaved insertion sequence and transformed to E. coil RRI. Triangles indicate insertion sites of the BamHl insertion element and brackets the deleted Sau3A fragments.The insertion element is a 4.7-kb DNA ...
... in the pBR322 vector portion, pWHI266 was partially digested with $au3A, ligated with the BamHl cleaved insertion sequence and transformed to E. coil RRI. Triangles indicate insertion sites of the BamHl insertion element and brackets the deleted Sau3A fragments.The insertion element is a 4.7-kb DNA ...
Exploring the genomic traits of fungus
... encodes the machinery required for the assembly of adhesive Flp (fimbrial low-molecule-weight protein) pili and is necessary for bacterial adhesion to surfaces, biofilm formation, and pathogenesis as shown for Aggregatibacter actinomycetemcomitans [14], Haemophilus [15], Pseudomonas [16], Yersinia e ...
... encodes the machinery required for the assembly of adhesive Flp (fimbrial low-molecule-weight protein) pili and is necessary for bacterial adhesion to surfaces, biofilm formation, and pathogenesis as shown for Aggregatibacter actinomycetemcomitans [14], Haemophilus [15], Pseudomonas [16], Yersinia e ...
Pairing of homologous regions in the mouse genome is associated
... larger regions of the chromosomes would come into close proximity, we used whole chromosome painting together with probes marking the KvDMR region and a region near the centromeric end of chromosome 7. Most nuclei showed two separate chromosome 7 domains which tended to be positioned away from each ...
... larger regions of the chromosomes would come into close proximity, we used whole chromosome painting together with probes marking the KvDMR region and a region near the centromeric end of chromosome 7. Most nuclei showed two separate chromosome 7 domains which tended to be positioned away from each ...
ARGONAUTE1 Acts in Arabidopsis Root Radial
... ellipsoidal cells in the outer layer and rectangular cells in the inner layers (Fig. 3H). In contrast, the corresponding region of ago1-101 scr-3 roots was filled with spherical cells with less radial stratification (Fig. 3I). Similar defects were observed in ago1-101 shr-2 double mutant roots (Fig. 3 ...
... ellipsoidal cells in the outer layer and rectangular cells in the inner layers (Fig. 3H). In contrast, the corresponding region of ago1-101 scr-3 roots was filled with spherical cells with less radial stratification (Fig. 3I). Similar defects were observed in ago1-101 shr-2 double mutant roots (Fig. 3 ...
2015 Pearson Education, Inc.
... Haploid cells have only one copy of each chromosome. Diploid cells have two copies of each chromosome. ...
... Haploid cells have only one copy of each chromosome. Diploid cells have two copies of each chromosome. ...
Molecular Evaluation of Vitamin D3 Receptor Agonists
... In the last few years several in vitro and cell culture methods have been developed that can be used for a molecular evaluation of the ef®cacy of the VDR±ligand interaction. One of the most powerful methods is the limited protease digestion assay, in which interaction of the VDR with a ligand protec ...
... In the last few years several in vitro and cell culture methods have been developed that can be used for a molecular evaluation of the ef®cacy of the VDR±ligand interaction. One of the most powerful methods is the limited protease digestion assay, in which interaction of the VDR with a ligand protec ...
Applications of Molecular genetics in - e
... CA and GT repeats, are most frequent. Also known as short tandem repeats or simple sequence repeats, microsatellites are polymorphic markers. An example of microsatellite containing “CA” repeats is given as following: ...
... CA and GT repeats, are most frequent. Also known as short tandem repeats or simple sequence repeats, microsatellites are polymorphic markers. An example of microsatellite containing “CA” repeats is given as following: ...
Lecture 2
... Having up to a million “isomorphic” classification problems per individual cries out for a parallel treatment. The RLMM/BRLMM strategy is to keep the individual classifiers simple - Mahalanobis - and put empirical priors over the parameters (means, variances) in the models. This hierarchical approac ...
... Having up to a million “isomorphic” classification problems per individual cries out for a parallel treatment. The RLMM/BRLMM strategy is to keep the individual classifiers simple - Mahalanobis - and put empirical priors over the parameters (means, variances) in the models. This hierarchical approac ...
Developing a CRISPR/Cas9 System for Volvox Carteri
... targeted mutations. The Cas9/CRISPR system is simpler and more precise than previously developed genome editing systems. The high precision is due to the CRISPR associated (Cas) endonuclease’s ability to bind DNA via associated guide RNAs. Cas endonucleases can delete or add bases to the genome, whi ...
... targeted mutations. The Cas9/CRISPR system is simpler and more precise than previously developed genome editing systems. The high precision is due to the CRISPR associated (Cas) endonuclease’s ability to bind DNA via associated guide RNAs. Cas endonucleases can delete or add bases to the genome, whi ...
Microsatellite Polymorphism in the Heme Oxygenase
... Previous studies indicate that tumor necrosis factor (TNF)α promoter polymorphism is one of the most frequently reported candidate host factors associated with CM in Africa as well as in Asia (12-14). In addition to TNF-α, many other genes have been postulated to be involved in the pathogenesis of C ...
... Previous studies indicate that tumor necrosis factor (TNF)α promoter polymorphism is one of the most frequently reported candidate host factors associated with CM in Africa as well as in Asia (12-14). In addition to TNF-α, many other genes have been postulated to be involved in the pathogenesis of C ...
Compound Heterozygous Beta Thalassemia
... acquired conditions. Heterozygous HPFH have an HbF level between10-35% and have benign course [1]. When these people tie to another bearer of the beta globin mutation, the expression in offspring carrying a compound heterozygous genotype vary widely. Molecular studies provide more honest penetration ...
... acquired conditions. Heterozygous HPFH have an HbF level between10-35% and have benign course [1]. When these people tie to another bearer of the beta globin mutation, the expression in offspring carrying a compound heterozygous genotype vary widely. Molecular studies provide more honest penetration ...
Control of Growth and of the Nuclear Division Cycle in Neurospora
... zoopfii (126), and in the slime mold Physarium polycephalum (124). Many data are also available on the yeast S. cerevisiae. Two groups of workers (19, 185) have shown that RNA per cell (or the RNA/DNA ratio) varies with the growth rate in batch cultures, although in a nonlinear fashion, and less sha ...
... zoopfii (126), and in the slime mold Physarium polycephalum (124). Many data are also available on the yeast S. cerevisiae. Two groups of workers (19, 185) have shown that RNA per cell (or the RNA/DNA ratio) varies with the growth rate in batch cultures, although in a nonlinear fashion, and less sha ...
On the monophyly of chromalveolates using a six
... of eukaryotes. One of these, the chromalveolates, represents a large fraction of protist and algal diversity. The chromalveolate hypothesis was originally based on similarities between the photosynthetic organelles (plastids) found in many of its members and has been supported by analyses of plastid ...
... of eukaryotes. One of these, the chromalveolates, represents a large fraction of protist and algal diversity. The chromalveolate hypothesis was originally based on similarities between the photosynthetic organelles (plastids) found in many of its members and has been supported by analyses of plastid ...
Tandem and segmental gene duplication and
... functionally distinct alleles, recognizing different varieties of a pathogen (e.g. the flax L locus and the Rpp13 locus of Arabidopsis), or only one resistant allele (e.g. Rpm1 and Rps2 of Arabidopsis thalina). Other R genes belong to families of tightly linked genes (clusters), some of which includ ...
... functionally distinct alleles, recognizing different varieties of a pathogen (e.g. the flax L locus and the Rpp13 locus of Arabidopsis), or only one resistant allele (e.g. Rpm1 and Rps2 of Arabidopsis thalina). Other R genes belong to families of tightly linked genes (clusters), some of which includ ...
Gene Duplication, Gene Conversion and the Evolution of
... Nonrecombining chromosomes, such as the Y, are expected to degenerate over time due to reduced efficacy of natural selection compared to chromosomes that recombine. However, gene duplication, coupled with gene conversion between duplicate pairs, can potentially counteract forces of evolutionary deca ...
... Nonrecombining chromosomes, such as the Y, are expected to degenerate over time due to reduced efficacy of natural selection compared to chromosomes that recombine. However, gene duplication, coupled with gene conversion between duplicate pairs, can potentially counteract forces of evolutionary deca ...
Cleavage - University of San Diego Home Pages
... To our limited intelligence, it would seem a simple task to divide a nucleus into equal parts. The cell, manifestly, entertains a very different opinion. E. B. Wilson, 1923 ...
... To our limited intelligence, it would seem a simple task to divide a nucleus into equal parts. The cell, manifestly, entertains a very different opinion. E. B. Wilson, 1923 ...
annotation and analysis of newly discovered mycobacteriophage
... for both essential and non-essential genes, in-frame internal deletions, point and nonsense mutations, gene tags, and specific insertions of genes from other organisms.2 Mycobacteriophage Background Bacteriophages are viruses that infect bacteria. They are the most abundant DNA containing entities o ...
... for both essential and non-essential genes, in-frame internal deletions, point and nonsense mutations, gene tags, and specific insertions of genes from other organisms.2 Mycobacteriophage Background Bacteriophages are viruses that infect bacteria. They are the most abundant DNA containing entities o ...