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Current - Indian Association for Cancer Research
Current - Indian Association for Cancer Research

... Smt. Mangala Bamane Award. In this session there were 9 young scientists who presented their work for about 10 minutes each. The day concluded by a key note address by Dr. E. Premkumar Reddy on “Chemical biological approaches for targeting the cancer genome”. He discussed various therapeutic strateg ...
5.3 Regulation of the Cell Cycle
5.3 Regulation of the Cell Cycle

... cycle are • a. kinases and cyclins. • b. hormones and enzymes. • c. phosphates and enzymes. • d. proteins and platelets. ...
Structural biology of viruses
Structural biology of viruses

... right of the molecule and is hidden through contacts to another protein in a homodimer. The anchor to the viral membrane is at the C-terminus of the protein, but this part of the protein was removed before crystallization and is therefore not seen here. ...
Assume that a particular genetic condition in a mammalian species
Assume that a particular genetic condition in a mammalian species

... Students were expected to be able to describe the most likely pattern of inheritance based on an understanding of Mendelian genetics and the specific information given to them in the question. They needed to relate that understanding to molecular genetics in their explanation of mutations as the cau ...
Prof. Emmanuelle Charpentier (France) Dr. Jennifer A. Doudna (USA)
Prof. Emmanuelle Charpentier (France) Dr. Jennifer A. Doudna (USA)

... converted into a revolutionary genome editing technology. It was an achievement that truly took the world by storm. When a bacterium is invaded by a foreign virus, the invader’s DNA is fragmented by the Cas enzyme and stored in the CRISPR locus as spacer sequences. If the bacterium detects the same ...
The contribution of tumorigenic stem cells to haematopoietic
The contribution of tumorigenic stem cells to haematopoietic

... The cycle of events that a cell completes from one division to the next is called the cell cycle. During the cell cycle the cell grows in size, it duplicates its hereditary material - that is, it copies the DNA molecules in the chromosomes - and it divides into two daughter cells. This year's Nobel ...
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Compare the activities of the enzymes in prokaryotic transcription to

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dna ppt
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... Sequence alignment • Why is this a problem? • The two sequences will differ by “substitutions”, “insertions” and “deletions” accumulated during evolution • The comparison algorithm has to be robust to such possibilities. – A special technique called “dynamic programming” does all this, and is “effi ...
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... without a change in DNA sequence, – often to the structure of the chromosome, – or through modification of the nucleotide bases, – or through post transcriptional regulation. ...
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... • The repressor binding to the operator interferes with binding of RNA Pol to the promoter, and therefore mRNA encoding LacZ and LacY is only made at very low levels. • When cells are grown in the presence of lactose, however, a lactose metabolite called allolactose , which is a combination of gluco ...
Solid Tumour Section Soft tissue tumors: t(X;20)(p11.23;q13.33) in biphasic synovial sarcoma
Solid Tumour Section Soft tissue tumors: t(X;20)(p11.23;q13.33) in biphasic synovial sarcoma

... Bottom: FISH cohybridization using a pool of RP11-552E4 and RP11-344N17 (red), RP5-1005F21 (purple), and pZ20 (green) as probes for chromosomes X, 20, and the two markers. The results on mar2 are shown as a three-color image (left), as well as separately for each of the probes (right). ...
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DNA microarrays and beyond: completing the journey from tissue to

... To date, most chip users have used two approaches. One is to use a form of replicate analysis (Fig. 1a, b). The other is to impose an arbitrary threshold of signal difference between experimental and control samples (fold-change), above which differences are considered to be real1,7. Each approach h ...
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gene_expression_info

... 4. Complimentary base pairs form H bonds between the codon and anticodon (UAC with the AUG) 5. Another tRNA (Pro) complimentary base pairs with the next codon in the ribosome at position A. 6. The enzyme peptidyl transferase forms a peptide bond between the two aa (met and Pro) 7. The first tRNA is ...
RNA - Gulf Coast State College
RNA - Gulf Coast State College

... fine as long as no triplet can code for more than one a.acid. • Note that several codons can also act as start (AUG) or stop (UAA) signals. ...
RNA - Gulf Coast State College
RNA - Gulf Coast State College

... fine as long as no triplet can code for more than one a.acid. • Note that several codons can also act as start (AUG) or stop (UAA) signals. ...
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...  A short sequence (R) is repeated at each end of the viral RNA, so the 5´ and 3´ ends are R-U5 and U3-R, respectively.  Reverse transcriptase starts synthesis when a tRNA primer binds to a site 100-200 bases from the 5´ end.  When the enzyme reaches the end, the 5´-terminal bases of RNA are degra ...
Cell membrane worksheet
Cell membrane worksheet

... Step 3. Read the following passage and mark up the text by underlining or circling the main terminologies or concepts. Put question marks next to the words you don’t understand. Do not use highlighters! The Cell Membrane Cell membranes are not rigid like an eggshell. Rather; they are fluid like a so ...
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HANDOUT: CH 18 pt 1 Study

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14.3 Studying the Human Genome
14.3 Studying the Human Genome

... The Human Genome Project was a 13-year international effort to sequence all 3 billion base pairs in human DNA and identify all human genes. The project was completed in 2003. ▶ The researchers identified markers in widely separated strands of DNA. ▶ They used “shotgun sequencing,” which uses a compu ...
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... applying the principles of modern genetics. ...
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biochem ch 18 [3-12

... When appropriate signal inactivates APC, β-catenin levels increase, and it travels to nucleus where it activates myc or cyclin D1 transcription, leading to cell proliferation o APC is tumor suppressor gene; if inactivated, it can’t bind β-catenin and inhibit cell proliferation  Mutations in APC or ...
DNA - Santa Susana High School
DNA - Santa Susana High School

... • DNA Replication is a semiconservative process where the new DNA is copied onto a parental (conserved) strand. It takes place with surprising efficiency and speed copying ~10 billion base pairs in a few hours with little or no errors. • Origin of replication: site of initiation of replication – bac ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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