K -Channel Transgenes Reduce K Currents in Paramecium
... (Doyle et al. 1998). Some channels are homotetramers, especially those overexpressed heterologously from a single subunit gene, whereas others appear to be heterotetramers. Jegla and Salkoff (1995) first described two K⫹-channel sequences from a Paramecium tetraurelia genomic library. We have expand ...
... (Doyle et al. 1998). Some channels are homotetramers, especially those overexpressed heterologously from a single subunit gene, whereas others appear to be heterotetramers. Jegla and Salkoff (1995) first described two K⫹-channel sequences from a Paramecium tetraurelia genomic library. We have expand ...
A process for analysis of microarray comparative genomics
... genomic DNA from the test and reference sample with different fluorescent dyes followed by co-hybridisation to the microarray slide. If a gene is conserved in both samples the fluorescence emitted at the corresponding position on the array will be a mixture derived from both labels. If the gene is p ...
... genomic DNA from the test and reference sample with different fluorescent dyes followed by co-hybridisation to the microarray slide. If a gene is conserved in both samples the fluorescence emitted at the corresponding position on the array will be a mixture derived from both labels. If the gene is p ...
An S Receptor Kinase Gene in Self-Compatible
... Because the A10 allele is not associated with self-incompatibility, it was not known whether this allele was genetically linked to the S locus or if it was present in another part of the Brassica genome. There are potentially two S loci in B. napus because it is composed of the genomes of both B. ca ...
... Because the A10 allele is not associated with self-incompatibility, it was not known whether this allele was genetically linked to the S locus or if it was present in another part of the Brassica genome. There are potentially two S loci in B. napus because it is composed of the genomes of both B. ca ...
Cytology of Genetics
... There are other models that have been proposed that address differences between what has been observed and what would be expected with the Holliday model. One such model is the Meselson-Radding model. ...
... There are other models that have been proposed that address differences between what has been observed and what would be expected with the Holliday model. One such model is the Meselson-Radding model. ...
Department of Biomedical Informatics
... most common form of genetic variation. As the name suggests, each SNP is a difference in a single nucleotide (A,T,C,or G) of an individual's DNA sequence, such as having AAGG instead of ATGG. There may be from 1 to 10 million SNPs in the entire human genome, but perhaps only a few thousand relate to ...
... most common form of genetic variation. As the name suggests, each SNP is a difference in a single nucleotide (A,T,C,or G) of an individual's DNA sequence, such as having AAGG instead of ATGG. There may be from 1 to 10 million SNPs in the entire human genome, but perhaps only a few thousand relate to ...
Visualization, description and analysis of the Drosophila melanogaster
... evolutionary process. On one hand, the molecule is intrinsically mutable, being this the origin of genetic variation. On the other hand, it allows the replication of old and new variants from one generation to another. The reproductive or survival advantage or disadvantage an individual has for carr ...
... evolutionary process. On one hand, the molecule is intrinsically mutable, being this the origin of genetic variation. On the other hand, it allows the replication of old and new variants from one generation to another. The reproductive or survival advantage or disadvantage an individual has for carr ...
rna, meet small molecules
... certain kinds of proteins are readily targetable by small molecules,” Gilman told BioCentury. Proteins need well-defined binding sites like the catalytic domains of enzymes or the ligand binding domains of receptors to be good targets for small molecules. Gilman estimates that only about 3,000 prote ...
... certain kinds of proteins are readily targetable by small molecules,” Gilman told BioCentury. Proteins need well-defined binding sites like the catalytic domains of enzymes or the ligand binding domains of receptors to be good targets for small molecules. Gilman estimates that only about 3,000 prote ...
- Cal State LA - Instructional Web Server
... Remaining Tasks Analyze the remaining sub-families Determine whether identified motifs agree across subfamilies BLAST motifs against all Alu sequences and correlate alignment scores with expression level ...
... Remaining Tasks Analyze the remaining sub-families Determine whether identified motifs agree across subfamilies BLAST motifs against all Alu sequences and correlate alignment scores with expression level ...
DNA MUTATION, REPAIR, AND TRANSPOSITION
... 2. Silent mutations are those that do not produce a detectable phenotypic change. They can occur in the region between genes, in introns, in the 5' and 3' untranslated regions of a gene, and in the wobble position of a codon. 4. Both types of mutation restore the wild-type function of a gene without ...
... 2. Silent mutations are those that do not produce a detectable phenotypic change. They can occur in the region between genes, in introns, in the 5' and 3' untranslated regions of a gene, and in the wobble position of a codon. 4. Both types of mutation restore the wild-type function of a gene without ...
1 Feline Hypertrophic Cardiomyopathy (HCM) Genetic Testing
... have HCM on an ultrasound exam should be eliminated from the breeding population. Cats with a positive HCM genetic test should be screened by ultrasound to determine disease status and this overall information used in breeding decisions. Other health, type, and behavioral attributes should certainly ...
... have HCM on an ultrasound exam should be eliminated from the breeding population. Cats with a positive HCM genetic test should be screened by ultrasound to determine disease status and this overall information used in breeding decisions. Other health, type, and behavioral attributes should certainly ...
2013 Holiday Lectures on Science Medicine in the Genomic Era
... strand is shown; t he sequence of the complementary DNA strand is not shown.) ...
... strand is shown; t he sequence of the complementary DNA strand is not shown.) ...
Caspary T, Cleary MA, Baker CC, Guan XJ, Tilghman SM. Mol Cell Biol. 1998 Jun;18(6):3466-74. Multiple mechanisms of imprinting on distal mouse chromosome 7.
... been shown for approximately 20 autosomal genes in mice and humans (4). A fundamental question about imprinting involves the mechanism used for distinguishing the maternal and paternal alleles of a gene. The leading candidate is DNA methylation that is established in different patterns in the male a ...
... been shown for approximately 20 autosomal genes in mice and humans (4). A fundamental question about imprinting involves the mechanism used for distinguishing the maternal and paternal alleles of a gene. The leading candidate is DNA methylation that is established in different patterns in the male a ...
Chapter 17
... • Three properties of RNA enable it to function as an enzyme – It can form a three-dimensional structure because of its ability to base pair with itself – Some bases in RNA contain functional groups – RNA may hydrogen-bond with other nucleic acid molecules ...
... • Three properties of RNA enable it to function as an enzyme – It can form a three-dimensional structure because of its ability to base pair with itself – Some bases in RNA contain functional groups – RNA may hydrogen-bond with other nucleic acid molecules ...
Articles - American Scientist
... within the mimivirus then apparentFigure 2. The genomes of giant viruses can be larger than those of some bacteria. These gely fuses with the surrounding memnomes are also packed with novelty. In the case of mimivirus (top), 86 percent of its predicted brane compartment, forming a conduit protein-co ...
... within the mimivirus then apparentFigure 2. The genomes of giant viruses can be larger than those of some bacteria. These gely fuses with the surrounding memnomes are also packed with novelty. In the case of mimivirus (top), 86 percent of its predicted brane compartment, forming a conduit protein-co ...
Horizontal Gene Transfer between Bacteria
... ‘Transfer’ refers to translocation of genetic material into a cell, followed by stable integration into the recipient genome, including autonomously-replicating components of the genome (e.g. a plasmid, accessory chromosome or organelle chromosome). The transferred gene can be perpetuated in the off ...
... ‘Transfer’ refers to translocation of genetic material into a cell, followed by stable integration into the recipient genome, including autonomously-replicating components of the genome (e.g. a plasmid, accessory chromosome or organelle chromosome). The transferred gene can be perpetuated in the off ...
Evolution of antifreeze glycoprotein gene from a trypsinogen gene in
... (i.e., PCR-amplification of the first-strand cDNA using the anchor primer and a primer designed from the 39 flanking sequence of AFGP gene that shares sequence identity with plaice trypsinogen cDNA). The 59 RACE-PCR products were cloned as a pool into pCRII, and one of the clones was isolated and se ...
... (i.e., PCR-amplification of the first-strand cDNA using the anchor primer and a primer designed from the 39 flanking sequence of AFGP gene that shares sequence identity with plaice trypsinogen cDNA). The 59 RACE-PCR products were cloned as a pool into pCRII, and one of the clones was isolated and se ...
Microcin B17 Blocks DNA Replication and Induces
... hypersensitive to microcin B 17. Strains producing a non-cleavable SOS repressor (lexA2 mutant) are also more sensitive than wild-type, whereas strains carrying a mutation which causes constitutive expression of the SOS response (spr-55) are less sensitive to microcin. Microcin B17 does not induce t ...
... hypersensitive to microcin B 17. Strains producing a non-cleavable SOS repressor (lexA2 mutant) are also more sensitive than wild-type, whereas strains carrying a mutation which causes constitutive expression of the SOS response (spr-55) are less sensitive to microcin. Microcin B17 does not induce t ...
Gene Expression in Prokaryotes
... An operon can be defined as a cluster gene that encode the proteins necessary to perform coordinated function Genes of the same operon have related functions within the cell and are turned on (expressed) and off together (suppressed). The first operon discovered was the lac operon so named because i ...
... An operon can be defined as a cluster gene that encode the proteins necessary to perform coordinated function Genes of the same operon have related functions within the cell and are turned on (expressed) and off together (suppressed). The first operon discovered was the lac operon so named because i ...
... Fire et al. (4) studied on the gene function especially on the gene responsible for movement in C.elegans. When this nematods were injected with the mixture of sense and antisense RNA, nematodes were observed with the impaired movement suggesting a defective muscle gene protein. They concluded that ...