Uracil in DNA – occurrence, consequences and repair
... replication fork because it has a turnover number (600 – 1000 per min) which is orders of magnitude higher than that of other uracil-DNA glycosylases. In Ung7/7 cells the steady state level of uracil in genomic DNA is approximately 2000 per cell, while it was below detection level, and at least 10-f ...
... replication fork because it has a turnover number (600 – 1000 per min) which is orders of magnitude higher than that of other uracil-DNA glycosylases. In Ung7/7 cells the steady state level of uracil in genomic DNA is approximately 2000 per cell, while it was below detection level, and at least 10-f ...
The Genetics of Alcohol Metabolism
... In higher organisms, including humans, the genes encoding the various components of the body are not just simple stretches of DNA that serve as a template from which proteins are generated. Instead, they have a complex structure involv ing, in some cases, dozens of pieces of coding sequences inters ...
... In higher organisms, including humans, the genes encoding the various components of the body are not just simple stretches of DNA that serve as a template from which proteins are generated. Instead, they have a complex structure involv ing, in some cases, dozens of pieces of coding sequences inters ...
A P element-homologous sequence in the house fly, Musca domestica
... of conservation differs for different species. One explanation for differing degrees of sequence conservation is that some P elements may have acquired additional or new functions in certain genomes. For example, in D. melanogaster, internally deleted P elements serve as a repressor of transposition ...
... of conservation differs for different species. One explanation for differing degrees of sequence conservation is that some P elements may have acquired additional or new functions in certain genomes. For example, in D. melanogaster, internally deleted P elements serve as a repressor of transposition ...
Overview of molecular methods in immunohematology
... Why not determine routine ABO and RHD by testing DNA? Like all donors, antigen-negative donors must have their ABO and Rh type determined. However, for several reasons DNA analysis is not the method of choice for routine ABO and D determination of donor blood. They include the following: the natural ...
... Why not determine routine ABO and RHD by testing DNA? Like all donors, antigen-negative donors must have their ABO and Rh type determined. However, for several reasons DNA analysis is not the method of choice for routine ABO and D determination of donor blood. They include the following: the natural ...
Role of Utility and Inference in the Evolution of Functional Information
... Information theory explores the statistical properties of signals but entirely ignores the meaning of the transmitted messages. Biosemiotics attempts to fill this gap by studying the meaning of the various kinds of information that are used by living organisms, including DNA sequences, cell signalin ...
... Information theory explores the statistical properties of signals but entirely ignores the meaning of the transmitted messages. Biosemiotics attempts to fill this gap by studying the meaning of the various kinds of information that are used by living organisms, including DNA sequences, cell signalin ...
A Comparative Gene Map of the Horse (Equus caballus)
... Type I loci In addition to amplifying gene-specific fragments, a key feature necessary for the effective use of PCR-based markers in synteny mapping with interspecific SCH panels is the ability to differentiate between fragments amplified from the donor species (i.e. horse) and the murine background ...
... Type I loci In addition to amplifying gene-specific fragments, a key feature necessary for the effective use of PCR-based markers in synteny mapping with interspecific SCH panels is the ability to differentiate between fragments amplified from the donor species (i.e. horse) and the murine background ...
Cleavage of a model DNA replication fork by a Type I restriction
... DNA replication is suggested by the restriction alleviation phenomena: the phenotypic decrease of restriction activity on invading DNA, it is induced by several DNA damaging agents or is constitutively seen in some mutants. The underlying mechanism varies among the enzyme subtypes. For EcoKI (Type I ...
... DNA replication is suggested by the restriction alleviation phenomena: the phenotypic decrease of restriction activity on invading DNA, it is induced by several DNA damaging agents or is constitutively seen in some mutants. The underlying mechanism varies among the enzyme subtypes. For EcoKI (Type I ...
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... The neuropilin-2 (NRP2) gene is localized to 2q34, an autism susceptibility locus. NRP2 has been demonstrated to both guide axons and to control neuronal migration in the central nervous system. It has been reported that NRP2 may be required in vivo for sorting migrating cortical and ...
... The neuropilin-2 (NRP2) gene is localized to 2q34, an autism susceptibility locus. NRP2 has been demonstrated to both guide axons and to control neuronal migration in the central nervous system. It has been reported that NRP2 may be required in vivo for sorting migrating cortical and ...
Bone Marrow Failure Associated with Herpesvirus 8 Infection in a
... between the latent and the lytic stages of the virus life cycle. Demonstration of HHV-8 mRNA by RT-PCR, especially of structural gene transcripts, appears to offer the most accurate reflection of viral replication. Detection of structural gene transcripts is indicative of chronic persistent infectio ...
... between the latent and the lytic stages of the virus life cycle. Demonstration of HHV-8 mRNA by RT-PCR, especially of structural gene transcripts, appears to offer the most accurate reflection of viral replication. Detection of structural gene transcripts is indicative of chronic persistent infectio ...
tRNA and Protein Building
... RNA produced in the nucleus of a cell moves out of the nucleus to the cell’s ribosomes. This RNA is a specific sequence of base copied from the DNA which carries the chromosomal genetic message to the cytoplasm. Thus, it is called messenger RNA (mRNA). At the ribosomes, mRNA directs the building of ...
... RNA produced in the nucleus of a cell moves out of the nucleus to the cell’s ribosomes. This RNA is a specific sequence of base copied from the DNA which carries the chromosomal genetic message to the cytoplasm. Thus, it is called messenger RNA (mRNA). At the ribosomes, mRNA directs the building of ...
Rules, regulations, and policies for breeding and biotechnology
... example noticeable in traits related to disease resistance in animals and to biomass in plants. A decade after the discovery of heterosis, the fact that many traits depend on many genes, so called quantitative traits, was understood and statistical models were developed to account for such traits in ...
... example noticeable in traits related to disease resistance in animals and to biomass in plants. A decade after the discovery of heterosis, the fact that many traits depend on many genes, so called quantitative traits, was understood and statistical models were developed to account for such traits in ...
Gene Finding by Computational Analysis
... • DNA is usually tightly wound around histone proteins and forms a chromosome • The total info stored in all chromosomes constitutes a genome • In most multi-cell organisms, every cell contains the same complete set of chromosomes – May have some small different due to mutation ...
... • DNA is usually tightly wound around histone proteins and forms a chromosome • The total info stored in all chromosomes constitutes a genome • In most multi-cell organisms, every cell contains the same complete set of chromosomes – May have some small different due to mutation ...
Bcmb625-XistPaper-26apr07clp
... Using 3D reconstruction analysis: - identify Xist domain via RNA FISH - identify repressed gene locations via DNA FISH ...
... Using 3D reconstruction analysis: - identify Xist domain via RNA FISH - identify repressed gene locations via DNA FISH ...
The Chlamydomonas genome project: a decade on
... the gene models in the genome (see below) because these regions do not often encode proteins but still have to be scanned. Furthermore, some gene finding algorithms will annotate large and spurious families of genes in repetitive sequences. In a process known as repeat masking, the genome is scanned ...
... the gene models in the genome (see below) because these regions do not often encode proteins but still have to be scanned. Furthermore, some gene finding algorithms will annotate large and spurious families of genes in repetitive sequences. In a process known as repeat masking, the genome is scanned ...
Minute Sketches - Paul D. Heideman
... adding words as they go. In this process, the user makes the connections between the physical relationships among concepts and associate the connections with the correct words. Later, recreating the sketch without words is faster, and the user may think the words without writing them on the sketch. ...
... adding words as they go. In this process, the user makes the connections between the physical relationships among concepts and associate the connections with the correct words. Later, recreating the sketch without words is faster, and the user may think the words without writing them on the sketch. ...
letters
... Next, we probed the functional relationship between EZH2 and DNA methyltransferases. As these proteins act as transcriptional repressors11,12,15, we investigated whether they can silence a common target gene. Recent work has identified several EZH2-target genes, including the MYT1 gene16. We first e ...
... Next, we probed the functional relationship between EZH2 and DNA methyltransferases. As these proteins act as transcriptional repressors11,12,15, we investigated whether they can silence a common target gene. Recent work has identified several EZH2-target genes, including the MYT1 gene16. We first e ...
MCB 371/372 - Gogarten Lab | UConn
... the CDD PSSMs from the NCBI’s FTP server, but these are not in the correct checkpoint format to act as seeds for a databank search. According to Eric Sayers from the NCBI help desk: Yes, indeed. The problem is that we produce two “flavors” of scoremats: one with intermediate data (frequencies) and o ...
... the CDD PSSMs from the NCBI’s FTP server, but these are not in the correct checkpoint format to act as seeds for a databank search. According to Eric Sayers from the NCBI help desk: Yes, indeed. The problem is that we produce two “flavors” of scoremats: one with intermediate data (frequencies) and o ...
Tps1 regulates the pentose phosphate pathway, nitrogen
... The coding sequence of TPS3, designated MG08707.5, was identified from the M. grisea genome sequence by homology to S. cerevisiae TPS3 (accession number NC_001145) ...
... The coding sequence of TPS3, designated MG08707.5, was identified from the M. grisea genome sequence by homology to S. cerevisiae TPS3 (accession number NC_001145) ...
NUCLEOTIDES AND NUCLEIC ACIDS
... quence in the cell’s DNA. A segment of a DNA molecule that contains the information required for the synthesis of a functional biological product, whether protein or RNA, is referred to as a gene. A cell typically has many thousands of genes, and DNA molecules, not surprisingly, tend to be very larg ...
... quence in the cell’s DNA. A segment of a DNA molecule that contains the information required for the synthesis of a functional biological product, whether protein or RNA, is referred to as a gene. A cell typically has many thousands of genes, and DNA molecules, not surprisingly, tend to be very larg ...
Protocol S1.
... Additional support for these conclusions is provided by the examples in Figure S5, which show that regulatory relationships become detectable as soon as samples of the relevant condition are added to the compendium. The figures show that LexA targets are only detectable when SOS response conditions ...
... Additional support for these conclusions is provided by the examples in Figure S5, which show that regulatory relationships become detectable as soon as samples of the relevant condition are added to the compendium. The figures show that LexA targets are only detectable when SOS response conditions ...