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Protein-coding genes in eukaryotic DNA
Protein-coding genes in eukaryotic DNA

... Finished sequence: a clone insert is contiguously sequenced with high quality standard of error rate 0.01%. There are usually no gaps in the sequence. Draft sequence: clone sequences may contain several regions separated by gaps. The true order and orientation of the pieces may not be known. ...
Key Stage 3 - DNA detectives
Key Stage 3 - DNA detectives

... seen. They needed to work it out, draw parallels with this and the starter activity.  Let each pair collect a copy of the bases sheet (page 3) and Scientist A sheet (cut out from page 4 of the pupil worksheet). They fold the sheet in half, glue the two sides then cut them out. If you have time stud ...
Dennis Vaughn1,John Jackson1, Matt Moscou24,Karin Werner24
Dennis Vaughn1,John Jackson1, Matt Moscou24,Karin Werner24

... all dominant or all recessive genes for specific phenotypic traits. This makes study of Mendelian inheritance through a population easy to study given that the phenotypes chosen are easily distinguishable and measurable even to high school students. One gene of interest used in the teaching module i ...
Slide 1
Slide 1

... CAAAAAAAAAAAAAAAAAAAAAAAA A • 306 base pairs long: This sequence remains the same, no matter where it is found in the genome ...
F. Mutation and Repair 1. Background on DNA Mutations
F. Mutation and Repair 1. Background on DNA Mutations

... 2. Common Types and Mechanisms of DNA Damage, Mutation and Repair a. The alteration of a single base pair (point mutation) can result from chemical damage followed by copying error b. The insertion or deletion of a single base pair (point mutation) during DNA replication c. Single-stranded and doubl ...
Chapter 5
Chapter 5

... advancing complexity of living organisms. 1. The idea is that during meiosis in sexually reproducing organisms, crossover mutations can form multiple copies of a gene, a chromosome or the entire genome. 2. The organism survived just fine with one copy so it only repairs damages (mutations) to one co ...
Workshop#7
Workshop#7

... GenBank. Learn how to read a GenBank flat file. Learn how to search GenBank for information. Understand difference between header, features and sequence. Distinguish between a primary database and secondary database. Homework #2 due today. Homework #3 due Tues. Oct. 9 ...
Supplementary Material and Methods
Supplementary Material and Methods

... discriminate the translocated and the non-translocated BCL2 alleles in cases 1 and 2 we first sequenced the coding regions of the BCL2 gene in cases 1 and 2 using genomic DNA from whole tissue sections. In case 1 we found one SNP whereas no SNP was detected in case 2. We designed specific primers to ...
Course Outline - Pima Community College
Course Outline - Pima Community College

... exploration, history and application of recombinant DNA technology, fundamentals of cell biology and genetics, the Human Genome Project, and bioethics. Also includes an emphasis on a variety of advanced biotechniques and skills. Prerequisite(s): BIO 112 and 131. ...
The corn snake genome sequenced for the first time
The corn snake genome sequenced for the first time

... identification of other mutations responsible for multiple variations of snake skin coloration will be greatly facilitated. This will allow us to save much time in our future research. As in amelanism, these spontaneous mutations that can appear randomly in any individual, are the fundamental fuel o ...
biotechnology: tools and applications
biotechnology: tools and applications

... Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
Lambda Gene Family
Lambda Gene Family

... recombination created vast number of genes for antibody formation • This introduced a new concept: targeted mutation or recombination of DNA: is it possible?? • Paradox: how could stability be maintained in C region and diversity exist in V region? ...
word - marric
word - marric

... subunits: a five-carbon pentose sugar, a phosphoric acid group, and one of four nitrogen bases. (For DNA these nitrogen bases are adenine, guanine, cytosine, or thymine.) DNA and RNA differ in a number of major ways. A DNA nucleotide contains a deoxyribose sugar, but RNA contains ribose sugar. The n ...
poster - GeoGenetics
poster - GeoGenetics

... Background Ancient DNA has been shown to survive in fossil material however, post-mortem DNA damage reactions, which fragment the DNA backbone into short pieces and generate hydrolytic and oxidative base derivatives, often limit the amount of DNA templates preserved. Since extraction methods are des ...
Slide 1
Slide 1

... paralogs, repeats, structural features, syntenic relationships, ChIP-chip data ... • Based on experimental data and computational predictions. ...
DNA Structure and Replication, and Virus Structure and Replication
DNA Structure and Replication, and Virus Structure and Replication

... What enzyme is responsible for breaking the hydrogen bonds that hold together the base pairs during replication? (also called “unzipping” the DNA strand) The enzyme helicase breaks the hydrogen bonds between nitrogen base pairs during DNA replication. What enzyme is responsible for proofreading the ...
DNA sequencing
DNA sequencing

... genome variation that is associated with a specific human disease, while the word polymorphism implies a variation that is neither harmful nor beneficial. However, scientists are now learning that many polymorphisms actually do affect a person's characteristics, though in more complex and sometimes ...
EOC Review 2 - Wayne County Public Schools
EOC Review 2 - Wayne County Public Schools

... make them unable to carry oxygen is ______. People who are heterozygous are immune to the mosquito carrying disease called ______________. ...
lecture_11(LP)
lecture_11(LP)

... The strands of DNA can come apart . . . and go back together! ...
Genetics and Heredity
Genetics and Heredity

... Statistics indicated a pattern. ...
Sickle cell / mutations
Sickle cell / mutations

... in the nucleotide sequence, or base pair sequence, of DNA. Most mutations are either neutral (they have no effect) or harmful, but occasionally mutations can actually cause a helpful change. Some mutations change only a single base in the DNA sequence – these are called point mutations. Other mutati ...
What is Bioinformatics? - UNC
What is Bioinformatics? - UNC

... computer science, and statistics to understand and organize the information associated with these molecules on a large scale ...
A Next Generation Sequencing Panel for DNA Typing of
A Next Generation Sequencing Panel for DNA Typing of

... individual identification. However, forensic analysis using NGS technology is challenging, as the DNA is often present in low copy number, highly degraded and contaminated. These features limit the quality and quantity of the usable DNA, and will thus require a highly accurate, reproducible, and rob ...
Ch. 13: DNA, RNA and Proteins
Ch. 13: DNA, RNA and Proteins

... • Proteins are made at ribosomes, out in the cytoplasm; either free or attached to rER • DNA opens and one side is ‘read’ and a copy is made • Can make multiple copies, send to lots of ribosomes, make lots of protein at once • RNA is edited and the final version, mRNA leaves the nucleus, carrying th ...
DNA (Deoxyribonucleic Acid)
DNA (Deoxyribonucleic Acid)

... DNA by the numbers •  Each cell has about 2 m of DNA. •  The average human has 75 trillion cells. •  The average human has enough DNA to go from the earth to the The earth is 150 billion m ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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