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Explaining the Likelihood Ratio in DNA Mixture
Explaining the Likelihood Ratio in DNA Mixture

... one's beliefs (or probability) based on data (6). He showed how to use evidence to revise our belief in a hypothesis. "Bayes theorem," popularized in the 19th century by Pierre-Simon Laplace (7), is the cornerstone of statistical inference based on mathematical probability. In the 1940s, Alan Turing ...
A fost luat în studiu caracterul multifoliolar deoarece acest caracter
A fost luat în studiu caracterul multifoliolar deoarece acest caracter

... From the F1 generation a plant (F1-M8), showing strong multileaflet character, was chosen to perform the bulk segregating analysis. Of the different types of molecular markers that have been developed for Medicago species two types were chosen for this study: RAPD (Random Amplified polymorphic DNA), ...
Rapid Selection of Multiple Gene Integrant for the Production of
Rapid Selection of Multiple Gene Integrant for the Production of

... acid and DNA sequence of them are different and this was the only reason of expression level difference. The previous reports about the expression of hirudin variants were studied about only one variant at one time even though two of them were tested in one organism. Several cases about the correlat ...
Molecular cloning and biochemical characterization of a
Molecular cloning and biochemical characterization of a

... PAGE and transferred to nitrocellulose membrane (Amersham). Western blot analysis was performed using the ECL protocol (Amersham) and a 1 : 5000 dilution of the pea LOX antibody [14]. Identification of lipoxygenase products Two hundred micrograms of proteins from soluble and microsomal fractions wer ...
Specialized Transduction by Bacteriophage P22 in Salmonella typhimurium: Genetic and Physical Structure of the Transducing Genomes and the Prophage Attachment Site.
Specialized Transduction by Bacteriophage P22 in Salmonella typhimurium: Genetic and Physical Structure of the Transducing Genomes and the Prophage Attachment Site.

... P22pro-I and P22pro-3 are specialized transducing derivatives of phage P22 that carry the proA and proB genes of Salmonella typhimurium. These genes lie immediately adjacent to the prophage attachment site on the bacterial chromosome. By examining DNA heteroduplexes in the electron microscope, we fo ...
Mutual Interactions of the Phosphate Groups in Locally Deformed
Mutual Interactions of the Phosphate Groups in Locally Deformed

... rating in DNA, but not solvent and ions, that grooves play crucial role in DNA bending (Zhurkin et al. 1979). We extend this result by two findings. First, the grooves play opposite roles in B- and A-DNA; bending is favoured into the major groove in the former structure while minor groove is the fav ...
Conjugative plasmids: vessels of the communal gene pool
Conjugative plasmids: vessels of the communal gene pool

... mean that many conferrable traits can be transferred between discrete replicating elements (chromosomes or plasmids) by the movement of relatively small fragments of DNA. Phylogenetic analyses of complete genomes have also shown that some prokaryotic genes are more likely to be transferred than othe ...
Gene Section ETV6 (ets variant 6) Atlas of Genetics and Cytogenetics
Gene Section ETV6 (ets variant 6) Atlas of Genetics and Cytogenetics

... constitutive activation of the kinase activity of the partner protein, modification of the original functions of a transcription factor, loss of function of the fusion gene, affecting ETV6 and the partner gene, activation of a proto-oncogene in the vicinity of a chromosomal translocation and dominan ...
Homologous Recombination Between Episomal Plasmids and Chromosomes in Yeast.
Homologous Recombination Between Episomal Plasmids and Chromosomes in Yeast.

... Revised copy accepted August 2, 1983 ABSTRACT ...
The Evolution of CONSTANS-Like Gene Families
The Evolution of CONSTANS-Like Gene Families

... American Society of Plant Biologists Copyright © 2003 American Society of Plant Biologists. All rights reserved. ...
cbb752-mg-spr09-bioinfo
cbb752-mg-spr09-bioinfo

... molecules (in the sense of physical-chemistry) and then applying “informatics” techniques (derived from disciplines such as applied math, CS, and statistics) to understand and organize the information associated with these molecules, on a large-scale. • Bioinformatics is a practical discipline with ...
p53 powerpoint
p53 powerpoint

... p53 Mutant Mice Develop Cancer ...
RESOURCE - Madison Central High
RESOURCE - Madison Central High

... Genotyping: a Brief History ........................................................................................................... 103 Restriction Fragment Length Polymorphism ............................................................................... 103 The Human Genome Project .......... ...
Genetics of Bacteriophage P22. II. Gene Order and Gene Function.
Genetics of Bacteriophage P22. II. Gene Order and Gene Function.

... A complete genetic map of the temperate Salmonella phage P22 has been constructed using a variety of methods. The map is circular, about 100 map units (percent recombination) in length, and shows clustering of related functions. The map order by function closely resembles the order reported for the ...
Identifying 3D expression domains by graph clustering
Identifying 3D expression domains by graph clustering

... that chromatin can be divided into several principal types. This was done by analyzing the  binding profiles of chromatin proteins using a 2­state HMM. For every protein the target and  non­target loci are determined and identifies the most likely segmentation of ‘bound’ and  ‘unbound’ loci. The typ ...
Translation Section 1 From Genes to Proteins Chapter 10
Translation Section 1 From Genes to Proteins Chapter 10

... • Both prokaryotic and eukaryotic cells are able to regulate which genes are expressed and which are not, depending on the cell’s needs. • The piece of DNA that overlaps the promoter site and serves as the on-off switch is called an operator. ...
Aminoacyl-tRNA Synthetase Production for Unnatural Amino Acid
Aminoacyl-tRNA Synthetase Production for Unnatural Amino Acid

... the subject of considerable research. This work focuses on two ideas for furthering that research. The first idea is the adaptation of CFPS to make proteins containing unnatural amino acids. Unnatural amino acids are not found in natural biological proteins; they are synthesized artificially to poss ...
J. Biol. Chem.
J. Biol. Chem.

... The covalent Top1-DNA intermediate is the cellular target of camptothecin (CPT) and clinically useful analogs, such as topotecan (TPT) and SN-38, the active metabolite of irinotecan (CPT-11) (reviewed in Refs. 2 and 4 – 6). These Top1 poisons reversibly stabilize the covalent Top1-DNA intermediate b ...
The Maize Genome Poster
The Maize Genome Poster

... Corn, also known as maize (from the Spanish maíz), was first domesticated nearly 10,000 years ago from teosinte, a wild grass that looked quite different from our modern crop. Teosinte grew in Mexico and Central America as a bushy plant with many spikes, the precursor to our familiar ear of corn. Th ...
A natural recessive resistance gene against potato virus
A natural recessive resistance gene against potato virus

... We show here that the pvr2 locus in pepper, conferring recessive resistance against strains of potato virus Y (PVY), corresponds to a eukaryotic initiation factor 4E (eIF4E) gene. RFLP analysis on the PVY-susceptible and resistant pepper cultivars, using an eIF4E cDNA from tobacco as probe, revealed ...
New Construct Approaches for Efficient Gene Silencing in Plants
New Construct Approaches for Efficient Gene Silencing in Plants

... transcriptional terminator. Here, we show that this regulatory element becomes obsolete when gene fragments are positioned between two oppositely oriented and functionally active promoters. The resulting convergent transcription triggers gene silencing that is at least as effective as unidirectional ...


... obtained from the cross Elgin × E420. The polymorphic fragment generated with primer UBC330 showed a 3:1 segregation ratio but was not linked to the Rps1 locus. Linkage analysis of the five RAPD markers that produce E420-specific bands along with two RFLP markers (Diers et al. 1992) relative to the ...
Comparative Analysis of Structural Diversity and
Comparative Analysis of Structural Diversity and

... a mitochondrial targeting presequence, compared with genes without a presequence? Is it common for a transferred gene to gain a presequence from another gene for a mitochondrial protein, or from a gene for a nonmitochondrial protein? How common are introns in different locations of the genes (preseq ...
software development and application in bioinformatics: single
software development and application in bioinformatics: single

... This thesis incorporates two projects, one in assessing software availability and application in detecting SNPs for next generation sequencing, and the other in software engineering of a social networking environment for use in biomedical informatics. SNP Detection: The study on variations in DNA se ...
Mutations in the MicroRNA Complementarity Site
Mutations in the MicroRNA Complementarity Site

... carpels. Our results suggest that the ICU4 gene has an adaxializing function and that it is down-regulated by microRNAs that require the HASTY protein for their biogenesis. ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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