localization of histone gene transcripts in newt lampbrush
... It is provided by the lampbrush chromosomes of Amphibia, where many RNA transcripts of DNA sequences on the lateral loops may lie as closely packed together as the size of RNA polymerase molecules permits (Miller & Beatty, 1969; Angelier & Lacroix, 1975; Scheer, Franke, Trendelenburg & Spring, 1976) ...
... It is provided by the lampbrush chromosomes of Amphibia, where many RNA transcripts of DNA sequences on the lateral loops may lie as closely packed together as the size of RNA polymerase molecules permits (Miller & Beatty, 1969; Angelier & Lacroix, 1975; Scheer, Franke, Trendelenburg & Spring, 1976) ...
Functions of DNA methylation: islands, start sites, gene bodies and
... cytosine; see BOX 1) — have emphasized that the position of the methylation in the transcriptional unit influences its relationship to gene control. For example, methylation in the immediate vicinity of the TSS blocks initiation, but methylation in the gene body does not block and might even stimula ...
... cytosine; see BOX 1) — have emphasized that the position of the methylation in the transcriptional unit influences its relationship to gene control. For example, methylation in the immediate vicinity of the TSS blocks initiation, but methylation in the gene body does not block and might even stimula ...
SNP
... they are in physical proximity and one fluorophore’s emission spectrum (the donor) overlaps the other’s (the acceptor) excitation spectrum. When FRET occurs the donor emission is quenched and the acceptor emission increases when the donor is excited FRET can be monitored by quenching of donor emissi ...
... they are in physical proximity and one fluorophore’s emission spectrum (the donor) overlaps the other’s (the acceptor) excitation spectrum. When FRET occurs the donor emission is quenched and the acceptor emission increases when the donor is excited FRET can be monitored by quenching of donor emissi ...
Biotechnology Book (May 2005)
... Biotechnology is a revolutionary and accessible concept that can boost agriculture and modernize overall economy of a country. The development and dependence on biotechnology has largely increased in countries all over the world especially in the last few years. The human Genome, production of antib ...
... Biotechnology is a revolutionary and accessible concept that can boost agriculture and modernize overall economy of a country. The development and dependence on biotechnology has largely increased in countries all over the world especially in the last few years. The human Genome, production of antib ...
LECTURE 13: EPIGENETICS – IMPRINTING Reading: Ch. 18, p
... normally. The only possible genetic difference between males and females in this experiment was the sex chromosomes, but even XX animals failed to thrive! We know now that one of the reasons that mammalian gynogenetic and androgenetic diploids cannot be made is because of an epigenetic phenomenon ca ...
... normally. The only possible genetic difference between males and females in this experiment was the sex chromosomes, but even XX animals failed to thrive! We know now that one of the reasons that mammalian gynogenetic and androgenetic diploids cannot be made is because of an epigenetic phenomenon ca ...
Castric et al. (MBE 2010) - GEPV
... of SI genes is the role played by recombination and/or gene conversion. Indeed, whether recombination occurs at all in the genomic region of the S-locus is still a debated topic. Although Wang et al. (2001) found recombinant haplotypes in Petunia inflata, and so direct evidence that intragenic recom ...
... of SI genes is the role played by recombination and/or gene conversion. Indeed, whether recombination occurs at all in the genomic region of the S-locus is still a debated topic. Although Wang et al. (2001) found recombinant haplotypes in Petunia inflata, and so direct evidence that intragenic recom ...
004 - cse.sc.edu
... • Automate computer work that you do by hand save time & reduce errors • Run the same analysis on lots of similar data files = scale-up • Analyze data, make decisions • sort Blast results by e-value &/or species of best mach ...
... • Automate computer work that you do by hand save time & reduce errors • Run the same analysis on lots of similar data files = scale-up • Analyze data, make decisions • sort Blast results by e-value &/or species of best mach ...
Studies on Polynucleotides
... dCTP were used. Experiment 3 in Table I shows the results obtained on nearest neighbor analysis of the product obtained when [cG2P]dCTP alone was used. As expected, the radi0activit.y Ivas in dAp and dCp, the ratio found being 1.3. The result may again indicate that the incorporation of the terminal ...
... dCTP were used. Experiment 3 in Table I shows the results obtained on nearest neighbor analysis of the product obtained when [cG2P]dCTP alone was used. As expected, the radi0activit.y Ivas in dAp and dCp, the ratio found being 1.3. The result may again indicate that the incorporation of the terminal ...
Genome-Wide Analysis of Natural Selection on
... regulatory elements (GREs) have a significant impact on evolution[2,3]. Since then, various lines of evidence have confirmed the functional impact of gene regulatory mutations[4]. The majority of known human polymorphisms occur in noncoding regions, many of which are likely to underlie gene expressi ...
... regulatory elements (GREs) have a significant impact on evolution[2,3]. Since then, various lines of evidence have confirmed the functional impact of gene regulatory mutations[4]. The majority of known human polymorphisms occur in noncoding regions, many of which are likely to underlie gene expressi ...
Supplementary Figures (doc 9746K)
... 3’ splice site; (4) new 5’ splice site; (5) intragenic; and (6) intergenic. The first two categories are junctions whose start and stop sites have been annotated in the Ensembl gene annotation. The only difference is that the new junction group uses different combinations of start and stop sites. Th ...
... 3’ splice site; (4) new 5’ splice site; (5) intragenic; and (6) intergenic. The first two categories are junctions whose start and stop sites have been annotated in the Ensembl gene annotation. The only difference is that the new junction group uses different combinations of start and stop sites. Th ...
Disruption of an N-acetyltransferase gene in the
... also associated with the melanic phenotypes. A 126 bp deletion in the mln genome causes two alternatively spliced transcripts with premature terminations. An enzymatic assay demonstrated the absolute loss of AANAT activity in the mutant proteins. We also performed RNA interference of AANAT in wild-t ...
... also associated with the melanic phenotypes. A 126 bp deletion in the mln genome causes two alternatively spliced transcripts with premature terminations. An enzymatic assay demonstrated the absolute loss of AANAT activity in the mutant proteins. We also performed RNA interference of AANAT in wild-t ...
The Arabidopsis STICHEL Gene Is a Regulator of Trichome Branch
... and were mapped based on sequence comparison with sequenced fragments of the IGF BACs. Molecular markers used for mapping are shown together with the recombination frequencies. The blowup of the chromosomal region between the two markers argyp and F8N6-sub#51 shows a higher resolution map and the pr ...
... and were mapped based on sequence comparison with sequenced fragments of the IGF BACs. Molecular markers used for mapping are shown together with the recombination frequencies. The blowup of the chromosomal region between the two markers argyp and F8N6-sub#51 shows a higher resolution map and the pr ...
20060710_GOannotCamp_Stanford
... Concept: Use all information from all papers about a single gene to annotate. Reality: A subset of the total papers associated with a gene has GO information, other papers have redundant or back-up information (from a GO perspective). Some MODs have ways of associating genes to papers (SGD, TAIR, MG ...
... Concept: Use all information from all papers about a single gene to annotate. Reality: A subset of the total papers associated with a gene has GO information, other papers have redundant or back-up information (from a GO perspective). Some MODs have ways of associating genes to papers (SGD, TAIR, MG ...
Predicting tRNA and tmRNA genes Aragorn - SEA
... “Transfer-messenger RNA (tmRNA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties. In trans-translation, tmRNA and its associated proteins bind to bacterial ribosomes which have stalled in the middle of protein biosynthesis, for example when reaching the end of a mess ...
... “Transfer-messenger RNA (tmRNA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties. In trans-translation, tmRNA and its associated proteins bind to bacterial ribosomes which have stalled in the middle of protein biosynthesis, for example when reaching the end of a mess ...
Molecular pathogenesis of feline leukemia virus
... Fig. 1. Concepts of retroviral insertional mutagenesis. The provirus contains long terminal repeats (LTRs) at both ends. LTRs can be subdivided into three regions: U3, R and U5. U3 contains the enhancer and promoter sequences that drive viral as well as cellular gene transcription. Retroviral gag, p ...
... Fig. 1. Concepts of retroviral insertional mutagenesis. The provirus contains long terminal repeats (LTRs) at both ends. LTRs can be subdivided into three regions: U3, R and U5. U3 contains the enhancer and promoter sequences that drive viral as well as cellular gene transcription. Retroviral gag, p ...
A global picture of tRNA genes in plant genomes
... monocots, respectively. The internal or external motifs required for efficient transcription of tRNA genes by RNA polymerase III are well conserved among angiosperms. A brief analysis of the mitochondrial and plastidial tRNA gene populations is also provided. Keywords: alga, angiosperm, non-coding R ...
... monocots, respectively. The internal or external motifs required for efficient transcription of tRNA genes by RNA polymerase III are well conserved among angiosperms. A brief analysis of the mitochondrial and plastidial tRNA gene populations is also provided. Keywords: alga, angiosperm, non-coding R ...
Predicting_tRNA_and_tmRNA_genes_12-2-16
... “Transfer-messenger RNA (tmRNA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties. In trans-translation, tmRNA and its associated proteins bind to bacterial ribosomes which have stalled in the middle of protein biosynthesis, for example when reaching the end of a mess ...
... “Transfer-messenger RNA (tmRNA) is a bacterial RNA molecule with dual tRNA-like and messenger RNA-like properties. In trans-translation, tmRNA and its associated proteins bind to bacterial ribosomes which have stalled in the middle of protein biosynthesis, for example when reaching the end of a mess ...
Characteristics of a Laboratory Strain of Coleomegilla maculata with
... phenotypic strains has not yet been examined or analyzed. Patterning in insects may be regulated by transcription factors such as optomotor-blind (omb) or bric a brac (bab) [11]. Color patterns in wings of butterflies are complex, and may be the product of the co-option of developmental pathways, as ...
... phenotypic strains has not yet been examined or analyzed. Patterning in insects may be regulated by transcription factors such as optomotor-blind (omb) or bric a brac (bab) [11]. Color patterns in wings of butterflies are complex, and may be the product of the co-option of developmental pathways, as ...
Analysis of clones carrying repeated DNA sequences in two YAC
... The purpose of the experiments described here was to identify and characterize YAC clones containing these main categories of repeated DNA sequences. This would enable chromosome walks into these highly repeated regions to be quickly recognized and terminated. YAC clones containing chimaeric inserts ...
... The purpose of the experiments described here was to identify and characterize YAC clones containing these main categories of repeated DNA sequences. This would enable chromosome walks into these highly repeated regions to be quickly recognized and terminated. YAC clones containing chimaeric inserts ...
Identification and characterization of putative conserved IAM
... sequences is computed using k-mer counting. A tree is then constructed from the triangular distance matrix computed from the pairwise similarities using UPGMA and a root is identified. The resulting tree is improved by building a new progressive alignment and a new tree is constructed by computing a ...
... sequences is computed using k-mer counting. A tree is then constructed from the triangular distance matrix computed from the pairwise similarities using UPGMA and a root is identified. The resulting tree is improved by building a new progressive alignment and a new tree is constructed by computing a ...
SOP Criteria for Variant Classification
... same set of data. e.g. if BS1 is applied based on ExAC data, then other data (such as parental data) is preferred to use if BS2 is to be applied too. ...
... same set of data. e.g. if BS1 is applied based on ExAC data, then other data (such as parental data) is preferred to use if BS2 is to be applied too. ...
Synthesis and Evaluation of Guanidino Phthalocyanines for G
... nucleotide bases, which form hydrogen-bonded pairs, are nearly perpendicular to the helix axis. The bases occupy the core of the helix while the sugar-phosphate backbones wind around the outside, forming the major and minor grooves. Only the edges of the base pairs are exposed to solvent. Each base ...
... nucleotide bases, which form hydrogen-bonded pairs, are nearly perpendicular to the helix axis. The bases occupy the core of the helix while the sugar-phosphate backbones wind around the outside, forming the major and minor grooves. Only the edges of the base pairs are exposed to solvent. Each base ...
CS790 – Introduction to Bioinformatics
... Prior to cell division, all the genetic instructions must be “copied” so that each new cell will have a complete set DNA polymerase is the enzyme that copies DNA • Reads the old strand in the 3´ to 5´ direction ...
... Prior to cell division, all the genetic instructions must be “copied” so that each new cell will have a complete set DNA polymerase is the enzyme that copies DNA • Reads the old strand in the 3´ to 5´ direction ...
Cell
... •the Drosophila genome is only 150 million bp (vs 3 billion bp in humans) •they did it! ...
... •the Drosophila genome is only 150 million bp (vs 3 billion bp in humans) •they did it! ...
RAD51 Gene 135G/C polymorphism and ovarian cancer risk: a meta
... incorrectly, eventually leading to genome instability or mutations which may lead to an increased susceptibility to cancer [17]. RAD51, a kind of ubiquitous strand exchange protein, is known to be a core component involved in DNA double-strand break repair in HR repair pathway [18]. The RAD51 gene 1 ...
... incorrectly, eventually leading to genome instability or mutations which may lead to an increased susceptibility to cancer [17]. RAD51, a kind of ubiquitous strand exchange protein, is known to be a core component involved in DNA double-strand break repair in HR repair pathway [18]. The RAD51 gene 1 ...