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GOPoster - Computational Biology and Informatics Laboratory
GOPoster - Computational Biology and Informatics Laboratory

... to protein domains as listed in ProDom and CDD is described. The algorithm generates rules for function-domain association based on the intersection of functions assigned to gene products by GO that contain ProDom and/or CDD domains at varying levels of sequence similarity. The hierarchical nature o ...
Title Heterochromatin Blocks Constituting the Entire
Title Heterochromatin Blocks Constituting the Entire

... Centromeres and telomeres of higher eukaryotes generally contain repetitive sequences, which often form pericentric or subtelomeric heterochromatin blocks. C-banding analysis of chromosomes of Azara’s owl monkey, a primate species, showed that the short arms of acrocentric chromosomes consist mostly ...
1 Introduction
1 Introduction

... topoisomerase IIβ (Austin et al, 1993). A large body of literature has been published about mutations within or near the putative ATP-binding sites, in the conserved nucleotide binding motif (residue 472-477), or at the active tyrosine site (review in Vassetzky et al, 1995). In contrast to the conse ...
Uracil in DNA
Uracil in DNA

... Uracil in viral DNA Two species of phage (viruses that infect bacteria) are known to have DNA genomes with only uracil and no thymine. We do not yet know whether these phages are representatives of an ancient life form that never evolved thymine DNA, or whether their uracil-substituted genomes are a ...
Tissue Engineering for In Vitro Analysis of Matrix Metalloproteinases
Tissue Engineering for In Vitro Analysis of Matrix Metalloproteinases

... DNA demonstrated that the presence of decorin prevented an increase in the matrix component production. C, Total collagen content normalized to DNA demonstrated a similar trend as the GAG data, although not statistically significant. D, Reverse Date of download: 4/29/2017 transcription–polymerase ch ...
Addendum D - Sounds of Wonder
Addendum D - Sounds of Wonder

... The message left this time goes beyond the Solfeggio System, so it won’t be reported here. However, the other pictures presented quite another picture. Obviously the geometric shape must have something to do with DNA, or why bequeath it to us? What seemed most obvious was the cube in the center, oth ...
Nonenzymatic Sequence-Specific Cleavage of Single
Nonenzymatic Sequence-Specific Cleavage of Single

... Figure 3. (Right) Autoradiogram of tne LU% aenaturing polyacrylamide gel. Lane I: Maxam-Gilbert chemical sequencing G reaction." Lane 2 Control of 'lP duplex labeled at the 5'-end with I2P containing no modified uridine (dTTP was used in the Klenow reaction. instead of MTdUTP), I pg of sonicated cal ...
Lecture 2
Lecture 2

... allowing more measurements to be made using a single chip These considerations all place more and more demands on the low-level analysis: to maintain the quality of existing measurements, and to obtain good new ones. ...
Figure 15 - GEP Community Server
Figure 15 - GEP Community Server

... chromosome function and gene expression. A subset of DNA binding proteins, including the transcription factors, exhibits sequence-specific affinity. Consequently, short conserved motifs are often found near transcription start sites (TSS), corresponding to sites where transcription factors bind to t ...
PDF
PDF

... Salinity is one of the major natural hazards hampering rice production. Approximately 20% of irrigated areas worldwide (about 45 million ha) are estimated to suffer from salinity problems by various degrees (FAO, 2010). 21.5 million hectares of land areas in Asia are affected by salinity and estimat ...
A Ribosomal Protein AgRPS3aE from Halophilic Aspergillus
A Ribosomal Protein AgRPS3aE from Halophilic Aspergillus

... salt-tolerant properties of AgRPS3aE were demonstrated in M. oryzae and two model plant species, Arabidopsis and tobacco. These observations provide strong evidence that AgRPS3aE confers salt tolerance not only in fungi but also in plants. Many studies have shown that ribosomal protein genes, includ ...
File
File

... 1) The top diagram depicts the very large regulatory region upstream of the Hoxd13 gene. The area between the slashes represents the DNA located between the promoter and the regulatory region. 2) The diagrams to the left of the bar graph show, first, the intact DNA and, next, the three altered DNA s ...
Influence of the environment and probes on rapid DNA sequencing
Influence of the environment and probes on rapid DNA sequencing

... the current with vacuum in between the electrodes is ∼ 0.1 aA at a bias of 0.1 V, i.e., orders of magnitude lower than the currents obtained with DNA in between the electrodes. Since we envision operating the nanopore/electrode device in a regime where the transverse field is much stronger than the ...
Introduction to the GCG Wisconsin Package
Introduction to the GCG Wisconsin Package

...  For non-coding nucleotide homology search, considering either reducing the word size from 11 to 6/7, or using the FASTA.  The number of scoring matrices is limited, BLOSUM62/45/80 and PAM70 available for – MATRix parameter. ...
Apolipoprotein A5, a Newly Identified Gene That Affects Plasma
Apolipoprotein A5, a Newly Identified Gene That Affects Plasma

... facilitated genome-wide strategies to uncover functional regions of the mammalian genome. With the increasing availability of genomic sequences from multiple species, comparative genomic approaches have proven to be a powerful means for annotating human sequence.1–3 A basic underlying hypothesis of ...
S-Phase Checkpoint Genes Safeguard High
S-Phase Checkpoint Genes Safeguard High

... phosphorylation requires Nbs1 (Kim et al., 2002b), a constituent of MRN (Mre11, Rad50, and Nbs1). MRN is a wellstudied protein complex required for double-strand break repair and is conserved across Eukaryotae (reviewed in D’Amours and Jackson, 2002; Wyman and Kanaar, 2002; Bradbury and Jackson, 200 ...
Introduction to the GCG Wisconsin Package
Introduction to the GCG Wisconsin Package

Apolipoprotein A5, a Newly Identified Gene That Affects Plasma
Apolipoprotein A5, a Newly Identified Gene That Affects Plasma

... facilitated genome-wide strategies to uncover functional regions of the mammalian genome. With the increasing availability of genomic sequences from multiple species, comparative genomic approaches have proven to be a powerful means for annotating human sequence.1–3 A basic underlying hypothesis of ...
From Genes to Proteins
From Genes to Proteins

... When the RNA nucleotides are added during transcription, they are linked together with covalent bonds. As RNA polymerase moves down the strand, a single strand of RNA grows. Behind RNA polymerase, the two strands of DNA close up by forming hydrogen bonds between complementary bases, re-forming the D ...
FREE Sample Here
FREE Sample Here

... Answer: adenine:thymine, guanine:cytosine Section: 1.3 32) What is meant by the term genetic code? Answer: The genetic code consists of a linear series of three adjacent nucleotides present in mRNA molecules. Section: 1.3 33) Compare and contrast nonenzymatic and enzymatic proteins. Answer: Both are ...
First slide - Plant Ontology
First slide - Plant Ontology

... “ontology” term is borrowed from philosophy to describe the concepts and relationships about certain knowledge domains; for practical reason, ontology is written as a set of definitions of controlled vocabularies with given hierarchical relationships to one another, and can easily ...
Specialized Transduction
Specialized Transduction

... (called λ doc, for defective, one cohesive end) are produced by an aberration of the normal packaging mechanism in which one of the DNA ends arises by cos cleavage and the other arises by a less specific cleavage of host DNA (45, 64). Lambda docL chromosomes have the λ left end and host DNA from the ...
The relationships of the New Zealand wrens
The relationships of the New Zealand wrens

... and salt concentration, the dissociated single strands of conspecific DNA will reassociate only with their homologous partners and the matching of complementary base pairs will be essentially perfect. Similarly, if the single-stranded DNA molecules of two different species are combined under conditi ...
Comprehension Question - We can offer most test bank and solution
Comprehension Question - We can offer most test bank and solution

... Strengths – Fruit flies have proven to be an excellent model system for studying aspects of biology that they share with humans. Fruit flies are simpler in structure and physiology than humans and have a much simpler genome. They are small and easy to raise, they have a short generation time, and th ...
Protein–DNA Interactions: Amino Acid Conservation and the Effects
Protein–DNA Interactions: Amino Acid Conservation and the Effects

... where binding is independent of DNA sequence; (ii) highly specific, where binding is specific and all members of the family target the same DNA sequence; and (iii) multi-specific, where binding is also specific, but individual family members target different DNA sequences. Overall, protein residues ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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