Feature Engaging with Molecular Form to Understand Function
... characteristic of life. When Watson and Crick published the structure of DNA, they noted that DNA base pairing creates a double-stranded form that provides a means of accurately copying the genetic information. Understanding this link between form and function is important for understanding the basi ...
... characteristic of life. When Watson and Crick published the structure of DNA, they noted that DNA base pairing creates a double-stranded form that provides a means of accurately copying the genetic information. Understanding this link between form and function is important for understanding the basi ...
Functional Divergence of the Nuclear Receptor NR2C1
... divergence within NRs. Combining these models can uncover functionally relevant patterns of evolution that may not be apparent when they are used in isolation (Schott et al. 2014). Prior to interpreting the modeling results, we carried out a suite of reliability and robustness analyses, which led us ...
... divergence within NRs. Combining these models can uncover functionally relevant patterns of evolution that may not be apparent when they are used in isolation (Schott et al. 2014). Prior to interpreting the modeling results, we carried out a suite of reliability and robustness analyses, which led us ...
Slide 1
... Thus, homologous stretches of nonfunctional DNA, on which selection does not operate and which evolve by random genetic drift, can be compared between two species to calculate the amount of sequence divergence. If the generation time and the time since the two species have diverged from each other a ...
... Thus, homologous stretches of nonfunctional DNA, on which selection does not operate and which evolve by random genetic drift, can be compared between two species to calculate the amount of sequence divergence. If the generation time and the time since the two species have diverged from each other a ...
Erp, an extracellular protein family specific to
... smegmatis and M. xenopi and the selected recombinant plasmids were sequenced. The DNA sequences were assembled and the deduced amino acid sequences were shown to contain repeated sequences based on the PGLTS motif, as already described for the M. tuberculosis and M. leprae proteins. Fig. 1 shows a s ...
... smegmatis and M. xenopi and the selected recombinant plasmids were sequenced. The DNA sequences were assembled and the deduced amino acid sequences were shown to contain repeated sequences based on the PGLTS motif, as already described for the M. tuberculosis and M. leprae proteins. Fig. 1 shows a s ...
Chromatin regulates origin activity in Drosophila follicle cells
... Supplementary Fig. S8). Among Rpd3-mutant clones comprised of five or fewer cells, 20% (n ¼ 41) had at least one large nucleus, and measurement of total 4,6-diamidino-2-phenylindole (DAPI) fluorescence indicated that they contained approximately twofold more DNA than neighbouring non-mutant cells (F ...
... Supplementary Fig. S8). Among Rpd3-mutant clones comprised of five or fewer cells, 20% (n ¼ 41) had at least one large nucleus, and measurement of total 4,6-diamidino-2-phenylindole (DAPI) fluorescence indicated that they contained approximately twofold more DNA than neighbouring non-mutant cells (F ...
1 X chromosome crossover formation and genome stability in
... fidelity propagation of unaltered genomic information across generations. Yet, germ cells in most metazoans also intentionally create double-strand breaks (DSBs) to promote DNA exchange between parental chromosomes, a process known as crossing over. Homologous recombination is employed in the repair ...
... fidelity propagation of unaltered genomic information across generations. Yet, germ cells in most metazoans also intentionally create double-strand breaks (DSBs) to promote DNA exchange between parental chromosomes, a process known as crossing over. Homologous recombination is employed in the repair ...
Lecture Notes with Key Figures PowerPoint - HMartin
... • Nucleotides can have one, two, or three phosphate groups and are called NMPs, NDPs, and NTPs, respectively. ...
... • Nucleotides can have one, two, or three phosphate groups and are called NMPs, NDPs, and NTPs, respectively. ...
HOMOLOGY IN BIOLOGY: A Problem for Naturalistic Science
... due to construction according to pre-existing patterns, i.e., to design. Ironically, therefore, Berra's analogy shows that phylogenetic homology is not sufficient to exclude design-based explanations. In order to demonstrate naturalistic evolution, it is necessary to show that the mechanism by whic ...
... due to construction according to pre-existing patterns, i.e., to design. Ironically, therefore, Berra's analogy shows that phylogenetic homology is not sufficient to exclude design-based explanations. In order to demonstrate naturalistic evolution, it is necessary to show that the mechanism by whic ...
Supplementary Figure Legends (doc 52K)
... Supplementary Figure S1. Cumulative 14CO2 recovered from incubations with 14C-labelled substrates (circles), and the respective removal of these hydrocarbons in incubations with the corresponding unlabelled substrates as measured by HPLC (naphthalene and phenanthrene) or GCMS (n-hexadecane) (squares ...
... Supplementary Figure S1. Cumulative 14CO2 recovered from incubations with 14C-labelled substrates (circles), and the respective removal of these hydrocarbons in incubations with the corresponding unlabelled substrates as measured by HPLC (naphthalene and phenanthrene) or GCMS (n-hexadecane) (squares ...
Integrating multi-scale data on homologous recombination into a
... The early stage of recognition during which strand exchange progresses rapidly encompasses much of the mystery of homologous recombination: what structural features allow the search to form the correct homologous pairing in much less than an hour? In principle, molecular modeling should be an approp ...
... The early stage of recognition during which strand exchange progresses rapidly encompasses much of the mystery of homologous recombination: what structural features allow the search to form the correct homologous pairing in much less than an hour? In principle, molecular modeling should be an approp ...
Genetic Markers for Sex Identification in Forensic DNA Analysis
... In forensic casework there is often a need to determine the sex of an individual based on DNA evidence in instances such as identification of victims of mass disaster, missing persons investigations, and sexual assault cases. Analysis of Y-specific target sequences on the Y chromosome is a largely e ...
... In forensic casework there is often a need to determine the sex of an individual based on DNA evidence in instances such as identification of victims of mass disaster, missing persons investigations, and sexual assault cases. Analysis of Y-specific target sequences on the Y chromosome is a largely e ...
Table S3 - BioMed Central
... Search in NCBI Gene ids, e.g. ‘123’ for human PLIN2. Translates discontinued NCBI Gene IDs if they have been replaced in later versions of the database. Does not include entries with old (discontinued) Gene IDs in results unless specifically set by the “Include ...
... Search in NCBI Gene ids, e.g. ‘123’ for human PLIN2. Translates discontinued NCBI Gene IDs if they have been replaced in later versions of the database. Does not include entries with old (discontinued) Gene IDs in results unless specifically set by the “Include ...
mart
... computer • well-defined structure • reproducible analyses • no need for network connection ...
... computer • well-defined structure • reproducible analyses • no need for network connection ...
video slide - Mrs. H-D
... Because only cells that can make both arginine and tryptophan (arg+ trp+ cells) can grow into colonies on minimal medium, the lack of colonies on the two control plates showed that no further mutations had occurred restoring this ability to cells of the mutant strains. Thus, each cell from the mixtu ...
... Because only cells that can make both arginine and tryptophan (arg+ trp+ cells) can grow into colonies on minimal medium, the lack of colonies on the two control plates showed that no further mutations had occurred restoring this ability to cells of the mutant strains. Thus, each cell from the mixtu ...
Genomic Gene Clustering Analysis of Pathways
... A potential source of overestimating the amount of clustering is the fact that genes frequently undergo tandem duplications. In our analysis, such tandem pairs would be assigned to the same pathway if the duplication was recent, yet would not necessarily reflect functional coupling. Both genes may h ...
... A potential source of overestimating the amount of clustering is the fact that genes frequently undergo tandem duplications. In our analysis, such tandem pairs would be assigned to the same pathway if the duplication was recent, yet would not necessarily reflect functional coupling. Both genes may h ...
Sterile, 24-well tissue culture plates are filled with melted minimal ... 1.0 ml per well using a repeating syringe. After the...
... that the mts(MN9) strain might carry a chromosomal aberration. When mts(MN9) was crossed with cpc-1 (CD86 or CD15) only three classes of segregants were observed: the two parental classes and a new class of slow germinating ascospores with slow vegetative growth. The latter is presumed to be a dupli ...
... that the mts(MN9) strain might carry a chromosomal aberration. When mts(MN9) was crossed with cpc-1 (CD86 or CD15) only three classes of segregants were observed: the two parental classes and a new class of slow germinating ascospores with slow vegetative growth. The latter is presumed to be a dupli ...
Compressed q-gram Indexing for Highly Repetitive Biological
... A weak point of these BWT-based indices is that, although counting the number of occurrences of pattern substrings is fast, retrieving their positions in the collection is relatively slow. This is particularly noticeable when searching for short sequences, which have many occurrences. In turn, this ...
... A weak point of these BWT-based indices is that, although counting the number of occurrences of pattern substrings is fast, retrieving their positions in the collection is relatively slow. This is particularly noticeable when searching for short sequences, which have many occurrences. In turn, this ...
DNA Sequence Variation in the Human Y Chromosome: Functions
... [3, 50]. Deletion of any of the three azoospermia (AZFa, AZFb or AZFc) factor(s) and some still unidentified regulatory elements located elsewhere in the genome have been suspected to be responsible for male infertility. Considerable overlap of the AZFb and AZFc regions encompassing a number of gene ...
... [3, 50]. Deletion of any of the three azoospermia (AZFa, AZFb or AZFc) factor(s) and some still unidentified regulatory elements located elsewhere in the genome have been suspected to be responsible for male infertility. Considerable overlap of the AZFb and AZFc regions encompassing a number of gene ...
Liquid Crystal Phases: Chiral Nematic Phase
... o Carl R. Woese first presented this independent RNA idea in late 1960s (Woese, C. The Genetic Code, Harper & Row, New York, 1967). o Walter Gilbert first used the phrase "RNA World" in 1986 (Gilbert, Walter, Nature, 1986) o DNA replication need proteins and enzymes while at the origin of life there ...
... o Carl R. Woese first presented this independent RNA idea in late 1960s (Woese, C. The Genetic Code, Harper & Row, New York, 1967). o Walter Gilbert first used the phrase "RNA World" in 1986 (Gilbert, Walter, Nature, 1986) o DNA replication need proteins and enzymes while at the origin of life there ...
2001_butterfield_THE SUGARCANE GENOME
... robustum and S. officinarum, and a monoploid number of 10 for ancestral Saccharum may indicate a more ancient origin for these species than S. spontaneum. This would agree with the conclusions of Wilson et al. (1999). An alternative explanation for preferential pairing, however, could be the presenc ...
... robustum and S. officinarum, and a monoploid number of 10 for ancestral Saccharum may indicate a more ancient origin for these species than S. spontaneum. This would agree with the conclusions of Wilson et al. (1999). An alternative explanation for preferential pairing, however, could be the presenc ...
- Global Genes
... Expectations of Gene Therapy The potential benefits of gene therapy are broad reaching. Like an expert archer poised to hit a bull’s-eye, researchers around the world are taking aim at minimizing the proliferation of rare diseases via gene therapy. Gene therapy goes further than just treating some o ...
... Expectations of Gene Therapy The potential benefits of gene therapy are broad reaching. Like an expert archer poised to hit a bull’s-eye, researchers around the world are taking aim at minimizing the proliferation of rare diseases via gene therapy. Gene therapy goes further than just treating some o ...
Evolution of Disintegrin Cysteine-Rich and
... Woessner (1991) considered that convergent evolution could explain such similarity. Convergent evolution could also be applied to explain the structural resemblance of the proteolytic motifs between snake venom MDCs and mammalian MMPs. Considering this possibility, the zinc-binding motif may have ar ...
... Woessner (1991) considered that convergent evolution could explain such similarity. Convergent evolution could also be applied to explain the structural resemblance of the proteolytic motifs between snake venom MDCs and mammalian MMPs. Considering this possibility, the zinc-binding motif may have ar ...
Operophtera brumata with pheromone-baited traps, December 2005
... terminals from Nova Scotia is not far from this site. It is quite possible that many of the winter moths we captured originated from sites many miles from where we caught them in traps. In other pheromone trap surveys, such as that done with gypsy moth, males sometimes fly 100 miles or more before c ...
... terminals from Nova Scotia is not far from this site. It is quite possible that many of the winter moths we captured originated from sites many miles from where we caught them in traps. In other pheromone trap surveys, such as that done with gypsy moth, males sometimes fly 100 miles or more before c ...
MS Word - VCU Secrets of the Sequence
... SNP, pronounced “snip”, is an acronym for Single Nucleotide Polymorphism. SNP’s are singlenucleotide substitutions of one base for another. Each SNP location in the genome can have up to four versions: one for each nucleotide, A, C, G, and T. However, not all single-nucleotide changes are SNP’s. To ...
... SNP, pronounced “snip”, is an acronym for Single Nucleotide Polymorphism. SNP’s are singlenucleotide substitutions of one base for another. Each SNP location in the genome can have up to four versions: one for each nucleotide, A, C, G, and T. However, not all single-nucleotide changes are SNP’s. To ...
Genes for Two Mitochondrial Ribosomal Proteins in
... Repeated transfer to the nucleus has led to a highly variable distribution of ribosomal protein and succinate dehydrogenase genes among mitochondrial genomes of angiosperms. This variability is highlighted by the complete sequence determination of the mitochondrial genomes of Arabidopsis (Unseld et ...
... Repeated transfer to the nucleus has led to a highly variable distribution of ribosomal protein and succinate dehydrogenase genes among mitochondrial genomes of angiosperms. This variability is highlighted by the complete sequence determination of the mitochondrial genomes of Arabidopsis (Unseld et ...