Sequences 5` to Translation Start Regulate
... tissue specificity of expression. The extra regions of nucleotide sequence conservation between SSU301 and SSU611 might contribute to the high expression levels of these two genes. Studies that define the c/s-acting elements in 5' promoter regions generally use deletion analysis of the pertinent seq ...
... tissue specificity of expression. The extra regions of nucleotide sequence conservation between SSU301 and SSU611 might contribute to the high expression levels of these two genes. Studies that define the c/s-acting elements in 5' promoter regions generally use deletion analysis of the pertinent seq ...
Genetics_Review_Jeopardy_
... During this process the DNA strands separate and one DNA strand is used to make mRNA, and during this process mRNA is used to produce proteins. What are transcription and translation? ...
... During this process the DNA strands separate and one DNA strand is used to make mRNA, and during this process mRNA is used to produce proteins. What are transcription and translation? ...
Mapping strategies for sequence reads (with focus on RNA-seq)
... uires a set of known junctions from the reference ond, the QPALMA pipeline’s initial mapping phase ...
... uires a set of known junctions from the reference ond, the QPALMA pipeline’s initial mapping phase ...
Slides
... §Successful information-based system involves conservation and transfer §DNA - stable structure that maximizes storage and duplication §RNA - more reactive with numerous roles in protein synthesis and gene expression regulation ...
... §Successful information-based system involves conservation and transfer §DNA - stable structure that maximizes storage and duplication §RNA - more reactive with numerous roles in protein synthesis and gene expression regulation ...
Complete Protocol
... 5. Composition of Buffers and Solutions ................................................................................................... 7 6. References .......................................................................................................................................... 7 7. R ...
... 5. Composition of Buffers and Solutions ................................................................................................... 7 6. References .......................................................................................................................................... 7 7. R ...
here - Genomes Unzipped
... mechanisms of gene regulation, analogous perhaps to A→I RNA editing [3]. An alternative explanation is that some RDD sites are technical artifacts due to errors in mapping sequencing reads to a reference genome or systematic sequencing errors. To evaluate this possibility, we examined the sequence a ...
... mechanisms of gene regulation, analogous perhaps to A→I RNA editing [3]. An alternative explanation is that some RDD sites are technical artifacts due to errors in mapping sequencing reads to a reference genome or systematic sequencing errors. To evaluate this possibility, we examined the sequence a ...
What is a functional genetic polymorphism?
... an associated polymorphism is not defined and must be surmised or extrapolated as an effect on the gene that contains this polymorphism. In rare cases, a polymorphism may be a nonsynonymous coding region variation that alters the gene product protein structure. Most common polymorphisms are potentia ...
... an associated polymorphism is not defined and must be surmised or extrapolated as an effect on the gene that contains this polymorphism. In rare cases, a polymorphism may be a nonsynonymous coding region variation that alters the gene product protein structure. Most common polymorphisms are potentia ...
When epigenetics meets alternative splicing: the roles of DNA
... in sequencing technologies have commenced a new era for studying genome-wide epigenetic factors, as well as new layers of splicing regulation. The available single-nucleotide-resolution data has made it possible to observe that exons, rather than flanking introns, are already marked at the DNA level ...
... in sequencing technologies have commenced a new era for studying genome-wide epigenetic factors, as well as new layers of splicing regulation. The available single-nucleotide-resolution data has made it possible to observe that exons, rather than flanking introns, are already marked at the DNA level ...
Telomere Shortening and Tumor Formation by Mouse Cells Lacking
... (vertebrates: (TTAGGG)n ) -contain non-coding DNA material -protect chromosomes -prevent fusions and degradation and a constant loss of important DNA from chromosome ends http://www.wissenschaft-online.de/sixcms/ media.php/912/thumbnails/Telomer1.jpg.644586.jpg ...
... (vertebrates: (TTAGGG)n ) -contain non-coding DNA material -protect chromosomes -prevent fusions and degradation and a constant loss of important DNA from chromosome ends http://www.wissenschaft-online.de/sixcms/ media.php/912/thumbnails/Telomer1.jpg.644586.jpg ...
A twist in sea urchin gastrulation and mesoderm specification
... The bHLH (basic helix-loop-helix) transcription factor, sea urchin myogenic factor-1 (SUM-1), plays an important role in myogenic determination during sea urchin embryogenesis. SUM-1-mediated transactivation is restricted to the mesenchyme lineages in transgenic sea urchin embryos, suggesting that o ...
... The bHLH (basic helix-loop-helix) transcription factor, sea urchin myogenic factor-1 (SUM-1), plays an important role in myogenic determination during sea urchin embryogenesis. SUM-1-mediated transactivation is restricted to the mesenchyme lineages in transgenic sea urchin embryos, suggesting that o ...
Identification and characterization of an early gene in the Lymantria
... SK(+) (Stratagene) to generate pDB120. This fragment contains two internal StyI sites (at nucleotide positions 430 and 1018, see Fig. 3). Digestion of pDB120 with StyI, end-filling the overhangs with Sequenase (USB), and religation, resulted in a subclone, pDB162, which contains a truncated form of ...
... SK(+) (Stratagene) to generate pDB120. This fragment contains two internal StyI sites (at nucleotide positions 430 and 1018, see Fig. 3). Digestion of pDB120 with StyI, end-filling the overhangs with Sequenase (USB), and religation, resulted in a subclone, pDB162, which contains a truncated form of ...
miRNA pptx - NUS School of Computing
... Improving miRNA Target Genes Prediction Rikky Wenang Purbojati ...
... Improving miRNA Target Genes Prediction Rikky Wenang Purbojati ...
DNA and RNA:
... shape and to speed up important chemical reactions such as photosynthesis and respiration. A cell will not live long if it cannot reliably create the proteins that it needs for survival. This chapter looks at how cells reliably make proteins. To place these ideas in the proper context, remember that ...
... shape and to speed up important chemical reactions such as photosynthesis and respiration. A cell will not live long if it cannot reliably create the proteins that it needs for survival. This chapter looks at how cells reliably make proteins. To place these ideas in the proper context, remember that ...
11.7 Repressor binds cooperatively at each operator using a helix
... 1. Phages have a lytic life cycle, in which infection of a host bacterium is followed by production of a large number of phage particles, lysis of the cell, and release of the viruses. 2. Lytic infection falls typically into three phases. In the first phase a small number of phage genes are transcri ...
... 1. Phages have a lytic life cycle, in which infection of a host bacterium is followed by production of a large number of phage particles, lysis of the cell, and release of the viruses. 2. Lytic infection falls typically into three phases. In the first phase a small number of phage genes are transcri ...
Chapter 12 Translation and the Genetic Code
... Hydrogen bondsbetween a hydrogen atom in a polar covalent bond & a second electronegative atom Ionic bondselectrostatic interaction two oppositely charged ions van der Waals interactionsinteractions between dipoles (requires close proximity and specific orientation) ...
... Hydrogen bondsbetween a hydrogen atom in a polar covalent bond & a second electronegative atom Ionic bondselectrostatic interaction two oppositely charged ions van der Waals interactionsinteractions between dipoles (requires close proximity and specific orientation) ...
Kallikrein-like prorenin-converting enzymes in inbred
... Kallikreins are a group of serine proteases and are distinguished by having serine residue at their active site. Their general function is to convert inactive pro-peptide into its biologically active form. In recent years, emerging evidence indicates that some kallikrein–kinin enzymes also play a ro ...
... Kallikreins are a group of serine proteases and are distinguished by having serine residue at their active site. Their general function is to convert inactive pro-peptide into its biologically active form. In recent years, emerging evidence indicates that some kallikrein–kinin enzymes also play a ro ...
Genetics: The Science of Heredity
... Mutations Mutations can cause a cell to produce an incorrect protein during protein synthesis. As a result, the organism’s trait, or phenotype, may be different from what it normally would have been. ...
... Mutations Mutations can cause a cell to produce an incorrect protein during protein synthesis. As a result, the organism’s trait, or phenotype, may be different from what it normally would have been. ...
Plant Telomere Biology
... natural ends of larger eukaryotic chromosomes had a similar structure. Presumably, these short simple repeats somehow defended chromosomes against the end replication problem and other assaults on their integrity. In 1988, Eric Richards, then a graduate with Fred Ausubel at Harvard, cloned telomeric ...
... natural ends of larger eukaryotic chromosomes had a similar structure. Presumably, these short simple repeats somehow defended chromosomes against the end replication problem and other assaults on their integrity. In 1988, Eric Richards, then a graduate with Fred Ausubel at Harvard, cloned telomeric ...
A Novel Two Domain-Fusion Protein in Cyanobacteria with
... Hlips 1–4 (encoded by hli1, hli2, hli3, and hli4, respectively) range in size from 50 to 73 amino acids. They all contain a short N-terminus region followed by a predicted TMH (Figure 2A). In contrast, Hlip5 (CYB_1999 in Synechococcus OS-B’ and CYA_0389 in Synechococcus OS-A) is 102 amino acids long ...
... Hlips 1–4 (encoded by hli1, hli2, hli3, and hli4, respectively) range in size from 50 to 73 amino acids. They all contain a short N-terminus region followed by a predicted TMH (Figure 2A). In contrast, Hlip5 (CYB_1999 in Synechococcus OS-B’ and CYA_0389 in Synechococcus OS-A) is 102 amino acids long ...
Is HP1 an RNA detector that functions both in repression and
... composition (James and Elgin, 1986; James et al., 1989). HP1 immunostaining on polytene chromosomes from Drosophila larval salivary glands was used to show enrichment of the protein in pericentric heterochromatin. Since that initial discovery, HP1 homologues have been found in species ranging from f ...
... composition (James and Elgin, 1986; James et al., 1989). HP1 immunostaining on polytene chromosomes from Drosophila larval salivary glands was used to show enrichment of the protein in pericentric heterochromatin. Since that initial discovery, HP1 homologues have been found in species ranging from f ...
Polymorphic miRNA-mediated gene regulation: contribution to
... However, it has recently become apparent that in many cases target mRNA levels are in fact reduced, albeit to a lesser degree than the protein levels - thus certainly not fully accounting for it. miRNAs were shown to accelerate deadenylation of maternal targets during early embryogenesis in zebrafis ...
... However, it has recently become apparent that in many cases target mRNA levels are in fact reduced, albeit to a lesser degree than the protein levels - thus certainly not fully accounting for it. miRNAs were shown to accelerate deadenylation of maternal targets during early embryogenesis in zebrafis ...
A laktóz (lac) operon – egy példa a prokarióta génszabályozásra
... Pasteur Institute in Paris, for their work in elucidating the regulatory mechanism of lac operon, received the Nobel Prize in Physiology or Medicine in 1965. They examined two mutations: induced mutations of coding and regulator regions. SLIDE 2 Structure of the lac operon-I The lac operon is the be ...
... Pasteur Institute in Paris, for their work in elucidating the regulatory mechanism of lac operon, received the Nobel Prize in Physiology or Medicine in 1965. They examined two mutations: induced mutations of coding and regulator regions. SLIDE 2 Structure of the lac operon-I The lac operon is the be ...
Document
... one in every 25 bases is edited on average, which leads to about 1 in every 8 codons being edited on average. In plant mitochondrial mRNAs, about 2% of the nucleotides are edited on average. In the remainder of this article, we briefly describe the editing events in these organisms. Then we focus fi ...
... one in every 25 bases is edited on average, which leads to about 1 in every 8 codons being edited on average. In plant mitochondrial mRNAs, about 2% of the nucleotides are edited on average. In the remainder of this article, we briefly describe the editing events in these organisms. Then we focus fi ...
Molecular cloning and functional characterisation of a glucose
... TATA-like motif at position 3107 with correlated CAP signal, as assessed using the EUKPROM algorithm (PC Gene, IntelliGenetics). The 5P upstream region of the initiation codon was found to be A+T-rich and harbouring a number of regulatory elements. Most striking was the presence of a putative proges ...
... TATA-like motif at position 3107 with correlated CAP signal, as assessed using the EUKPROM algorithm (PC Gene, IntelliGenetics). The 5P upstream region of the initiation codon was found to be A+T-rich and harbouring a number of regulatory elements. Most striking was the presence of a putative proges ...
Genes & Inheritance Series: Set 3 Copyright © 2005 Version: 2.0
... Cells need to control the rate and frequency of protein synthesis. These controls often occur at transcription. Sometimes genes are induced (and therefore transcribed) only when an enzyme product is required to catalyze reactions that may occur infrequently, e.g. use of a particular substrate that i ...
... Cells need to control the rate and frequency of protein synthesis. These controls often occur at transcription. Sometimes genes are induced (and therefore transcribed) only when an enzyme product is required to catalyze reactions that may occur infrequently, e.g. use of a particular substrate that i ...
Non-coding RNA
A non-coding RNA (ncRNA) is an RNA molecule that is not translated into a protein. Less-frequently used synonyms are non-protein-coding RNA (npcRNA), non-messenger RNA (nmRNA) and functional RNA (fRNA). The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene.Non-coding RNA genes include highly abundant and functionally important RNAs such as transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as RNAs such as snoRNAs, microRNAs, siRNAs, snRNAs, exRNAs, and piRNAs and the long ncRNAs that include examples such as Xist and HOTAIR (see here for a more complete list of ncRNAs). The number of ncRNAs encoded within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest the existence of thousands of ncRNAs., but see Since many of the newly identified ncRNAs have not been validated for their function, it is possible that many are non-functional. It is also likely that many ncRNAs are non functional (sometimes referred to as Junk RNA), and are the product of spurious transcription.