The universal reagent for genome tailoring
... Another variation of this approach is pronuclear injection of a Cre expression vector, and the resultant transient Cre expression does its job during preimplantation development (Araki et al., 1995). Injecting Cre RNA or protein itself may also work. These latter three means are obviously more tedio ...
... Another variation of this approach is pronuclear injection of a Cre expression vector, and the resultant transient Cre expression does its job during preimplantation development (Araki et al., 1995). Injecting Cre RNA or protein itself may also work. These latter three means are obviously more tedio ...
Mothers against dpp participates in a DPP/TGF
... factor-β (TGF-β) superfamily are required for control of many aspects of cell growth, patterning and differentiation in many organisms (Kingsley, 1994). Receptor serine-threonine kinases on the surface of responsive cells are activated by these secreted molecules and thereby initiate an intracellula ...
... factor-β (TGF-β) superfamily are required for control of many aspects of cell growth, patterning and differentiation in many organisms (Kingsley, 1994). Receptor serine-threonine kinases on the surface of responsive cells are activated by these secreted molecules and thereby initiate an intracellula ...
Genetic polymorphisms of vein wall remodeling in chronic venous
... The ECM is a complex and dynamic framework of collagen, proteoglycans, elastin, glycoproteins, and cellular components. Degradation or destruction of the ECM disrupts the homeostasis of the vein (much of which is maintained by the MMPs, discussed later), thereby leading to varicosity. Vein wall weak ...
... The ECM is a complex and dynamic framework of collagen, proteoglycans, elastin, glycoproteins, and cellular components. Degradation or destruction of the ECM disrupts the homeostasis of the vein (much of which is maintained by the MMPs, discussed later), thereby leading to varicosity. Vein wall weak ...
Nuclear Envelope, Nuclear Lamina, and Inherited Disease
... homology domains and a carboxyl-terminal region containing a distinct functional domain. The carboxyl-terminal regions function in activities such as a membrane association, intermediate filament binding and microtubule binding. Nesprins have this general structure with a transmembrane segment in t ...
... homology domains and a carboxyl-terminal region containing a distinct functional domain. The carboxyl-terminal regions function in activities such as a membrane association, intermediate filament binding and microtubule binding. Nesprins have this general structure with a transmembrane segment in t ...
Application title: Cloning genes for expression in AAV vectors for
... low rate of quasi-random integration (10-3-10-4) (Lin and Ertl, 2008). In dogs, rAAV was demonstrated to persist episomally for up to 8 years with no evidence of chromosomal DNA integration (Niemeyer et al., 2009). However, if rAAV vectors are specifically designed to contain large stretches of unin ...
... low rate of quasi-random integration (10-3-10-4) (Lin and Ertl, 2008). In dogs, rAAV was demonstrated to persist episomally for up to 8 years with no evidence of chromosomal DNA integration (Niemeyer et al., 2009). However, if rAAV vectors are specifically designed to contain large stretches of unin ...
Identification of Mga1, a G‐protein α‐subunit gene involved in
... Heterotrimeric G-proteins consist of three subunits: Ga, Gb and Gg. They function as ‘molecular switches’ in G-protein signalling pathways to regulate the duration and intensity of the signal, eventually going on to regulate downstream cell processes. Most characterized filamentous fungi possess thr ...
... Heterotrimeric G-proteins consist of three subunits: Ga, Gb and Gg. They function as ‘molecular switches’ in G-protein signalling pathways to regulate the duration and intensity of the signal, eventually going on to regulate downstream cell processes. Most characterized filamentous fungi possess thr ...
The Effect of OmpA Expression on Hfr Conjugation Efficiency
... different classes (A1-A3) of conjugation-deficient OmpA mutants in which mutants may have differing susceptibilities to bacteriophages. These mutants lack detectable amounts of OmpA polypeptide (A1), have normal amounts of OmpA (A2), or have detectable but reduced amounts of OmpA protein (A3). These ...
... different classes (A1-A3) of conjugation-deficient OmpA mutants in which mutants may have differing susceptibilities to bacteriophages. These mutants lack detectable amounts of OmpA polypeptide (A1), have normal amounts of OmpA (A2), or have detectable but reduced amounts of OmpA protein (A3). These ...
Analysis of TALE superclass homeobox genes
... HAC (2). However, this analysis was incomplete and this group of genes has now been identified as the Meis genes (13,23,24). An unfinished cosmid sequence (T28F12, Genome Sequencing Center, personal communication) matching ceh-25 was found in the C.elegans genome project. Analysis of the ceh-25 regi ...
... HAC (2). However, this analysis was incomplete and this group of genes has now been identified as the Meis genes (13,23,24). An unfinished cosmid sequence (T28F12, Genome Sequencing Center, personal communication) matching ceh-25 was found in the C.elegans genome project. Analysis of the ceh-25 regi ...
TAN Huarong
... is easily degraded in nature. Nikkomycin biosynthesis has been investigated extensively, but the biosynthetic pathway remains unknown. In order to elucidate the pathway and to improve nikkomycin productivity, the gene cluster of nikkomycin biosynthesis has been cloned and sequenced. The function of ...
... is easily degraded in nature. Nikkomycin biosynthesis has been investigated extensively, but the biosynthetic pathway remains unknown. In order to elucidate the pathway and to improve nikkomycin productivity, the gene cluster of nikkomycin biosynthesis has been cloned and sequenced. The function of ...
Mannose binding lectin and FccRIIa (CD32
... SSP–PCR and SSOP techniques as described. However, a number of individuals could not be haplotyped using these methods alone due to each sample possessing only structurally encoding wild alleles as determined by SSP– PCR and being positive for X, Y, L and H polymorphisms. In such a situation, it was ...
... SSP–PCR and SSOP techniques as described. However, a number of individuals could not be haplotyped using these methods alone due to each sample possessing only structurally encoding wild alleles as determined by SSP– PCR and being positive for X, Y, L and H polymorphisms. In such a situation, it was ...
Bacterial plasmids - Micro-Rao
... the chromosome were earlier called episomes. Plasmids differ from chromosomes in being small and coding for genes that are non-essential for the bacterial survival. Absence of plasmids doesn’t kill bacterium, but their presence provides additional benefits to the bacterial cell. Plasmids vary in siz ...
... the chromosome were earlier called episomes. Plasmids differ from chromosomes in being small and coding for genes that are non-essential for the bacterial survival. Absence of plasmids doesn’t kill bacterium, but their presence provides additional benefits to the bacterial cell. Plasmids vary in siz ...
`Candidatus Midichloria mitochondrii`, an endosymbiont of the tick
... family rank: the Rickettsiaceae and the Anaplasmataceae. The six genera of the order also form well-defined monophyletic clusters within the two families: Rickettsia and Orientia within the Rickettsiaceae and Anaplasma, Wolbachia, Ehrlichia and Neorickettsia within the Anaplasmataceae. The family An ...
... family rank: the Rickettsiaceae and the Anaplasmataceae. The six genera of the order also form well-defined monophyletic clusters within the two families: Rickettsia and Orientia within the Rickettsiaceae and Anaplasma, Wolbachia, Ehrlichia and Neorickettsia within the Anaplasmataceae. The family An ...
Activation of Silent Genes by Transposons Tn5 and TnlO
... are absolutely polar; they block normal transcription of the target region and their own transcripts are terminatedbeforereachingthenextdownstream gene. This suggests that polarity sites are common and areusually present within the untranslated region downstream of the element. Insertions activate t ...
... are absolutely polar; they block normal transcription of the target region and their own transcripts are terminatedbeforereachingthenextdownstream gene. This suggests that polarity sites are common and areusually present within the untranslated region downstream of the element. Insertions activate t ...
Gene Section CTSH (cathepsin H) Atlas of Genetics and Cytogenetics
... The cathepsin H gene has a TATA- and CAAT-less promoter and upstream of exon 1 only one GC box was detected, suggesting the presence of one more exon. Two different forms of cathepsin H cDNA, the fulllength form (CTSH) and a truncated form with deletion of 12 amino acids at the signal peptide region ...
... The cathepsin H gene has a TATA- and CAAT-less promoter and upstream of exon 1 only one GC box was detected, suggesting the presence of one more exon. Two different forms of cathepsin H cDNA, the fulllength form (CTSH) and a truncated form with deletion of 12 amino acids at the signal peptide region ...
Is there a gene for liking broccoli?
... Maybe you are a broccoli fan, or maybe you just can’t stand the taste. Scientists are interested in learning more about why we eat specific foods. Taste is one of the sensory factors that is important in determining what we eat, so it is an important topic for scientific research. The tastes we can ...
... Maybe you are a broccoli fan, or maybe you just can’t stand the taste. Scientists are interested in learning more about why we eat specific foods. Taste is one of the sensory factors that is important in determining what we eat, so it is an important topic for scientific research. The tastes we can ...
GROW`N`GLOW: THE ACE1 TWO-HYBRID
... bioluminescent cnidarian Aequorea victoria4 and the metallothionein encoding CUP1 gene5. ...
... bioluminescent cnidarian Aequorea victoria4 and the metallothionein encoding CUP1 gene5. ...
Human Heredity - Cloudfront.net
... In order to apply Mendelian genetics to humans, biologists must identify an inherited trait controlled by a single gene. They must establish that the trait is inherited and not the result of environmental influences. They have to study how the trait is passed from one generation to the next. Slide 9 ...
... In order to apply Mendelian genetics to humans, biologists must identify an inherited trait controlled by a single gene. They must establish that the trait is inherited and not the result of environmental influences. They have to study how the trait is passed from one generation to the next. Slide 9 ...
Document
... • Established function of intracellular trafficking of transmembrane proteins to cell surface • linked with depression in both humans and animal models • ↓ levels in post-mortem brain tissues of depressed individuals – P11 knockout (KO) mice display a depression-like phenotype ...
... • Established function of intracellular trafficking of transmembrane proteins to cell surface • linked with depression in both humans and animal models • ↓ levels in post-mortem brain tissues of depressed individuals – P11 knockout (KO) mice display a depression-like phenotype ...
Biology
... was published. In a few cases, biologists were able to identify genes that directly control a single human trait such as blood type. Slide 13 of 43 Copyright Pearson Prentice Hall ...
... was published. In a few cases, biologists were able to identify genes that directly control a single human trait such as blood type. Slide 13 of 43 Copyright Pearson Prentice Hall ...
module 3: transcription part ii
... first. Let’s examine the beginning of the tra gene. Type "contig1:9,825-9,870" into the "position/search" textbox and then click on the "jump" button. In Module 2, we identified the transcription start site (TSS) of the A isoform of tra at position 9,851. To show the TSS's that have been annotated b ...
... first. Let’s examine the beginning of the tra gene. Type "contig1:9,825-9,870" into the "position/search" textbox and then click on the "jump" button. In Module 2, we identified the transcription start site (TSS) of the A isoform of tra at position 9,851. To show the TSS's that have been annotated b ...
3.14 C: Genetic Disorders Quiz PROCTOR VERSION
... Scientists use observable evidence to direct their questions about phenomena. For which question would the karyotype provide the most evidence? ...
... Scientists use observable evidence to direct their questions about phenomena. For which question would the karyotype provide the most evidence? ...
Homeotic selector genes
... • many HOM-C genes have autoregulatory binding sites in their promoters – but positive feedback, in itself, is insufficient to maintain memory without other factors – another group of genes, the Polycomb group, are required to repress homeotic selector genes that should not be expressed in a particu ...
... • many HOM-C genes have autoregulatory binding sites in their promoters – but positive feedback, in itself, is insufficient to maintain memory without other factors – another group of genes, the Polycomb group, are required to repress homeotic selector genes that should not be expressed in a particu ...
3 Shapes of Bacteria
... Endospore•a thick celled structure that forms inside the cell •they are the major cause of food poisoning •allows the bacteria to survive for many years •they can withstand boiling, freezing, and extremely dry conditions •it encloses all the nuclear materials and some cytoplasm ...
... Endospore•a thick celled structure that forms inside the cell •they are the major cause of food poisoning •allows the bacteria to survive for many years •they can withstand boiling, freezing, and extremely dry conditions •it encloses all the nuclear materials and some cytoplasm ...
Blue cone monochromacy: Causative mutations and associated
... (BCM), and to determine the underlying molecular genetic basis of disease. Methods: Affected members of three British families with BCM were examined clinically and underwent detailed electrophysiological and psychophysical testing. Blood samples were taken for DNA extraction. Molecular analysis inv ...
... (BCM), and to determine the underlying molecular genetic basis of disease. Methods: Affected members of three British families with BCM were examined clinically and underwent detailed electrophysiological and psychophysical testing. Blood samples were taken for DNA extraction. Molecular analysis inv ...
tAIg = w
... them to have a threefold difference in translation rate (21.6 and 6.4 codons per second, respectively). Remarkably, the wi of these codons, which is based on the tRNA pool and affinity of codon-anti-codon coupling and is the basis for the tAI calculation, captures the ratio of translation rate betwe ...
... them to have a threefold difference in translation rate (21.6 and 6.4 codons per second, respectively). Remarkably, the wi of these codons, which is based on the tRNA pool and affinity of codon-anti-codon coupling and is the basis for the tAI calculation, captures the ratio of translation rate betwe ...