 
									
								
									Gene Section NFATC2 (nuclear factor of activated T cells, cytoplasmic, calcineurin
									
... © 2013 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
                        	... © 2013 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
									Describe the operon hypothesis and discuss
									
... promoter site repressor site operator site structural genes inducer Function Max. 4 binds RNA polymerase* at 3' site on DNA (* also cAMP-CAP) produces repressor protein: stops RNA polymerase attaching to promoter site of attachment of repressor protein codes for sequential protein serves to inactiva ...
                        	... promoter site repressor site operator site structural genes inducer Function Max. 4 binds RNA polymerase* at 3' site on DNA (* also cAMP-CAP) produces repressor protein: stops RNA polymerase attaching to promoter site of attachment of repressor protein codes for sequential protein serves to inactiva ...
									Quiz 2
									
... all the cells are still dividing and can make any of the specialized cell types the embryo will need. Even later in development, stem cells are present in the body Usually, they only make one kind of cell ( fro example, blood or skin), but one of the unique properties of stem cells is that they can ...
                        	... all the cells are still dividing and can make any of the specialized cell types the embryo will need. Even later in development, stem cells are present in the body Usually, they only make one kind of cell ( fro example, blood or skin), but one of the unique properties of stem cells is that they can ...
									Intermolecular Interactions
									
... for the specific function; then clone the gene(s), mutate or knock them out (down) and demonstrate altered function (biochemistry+reverse genetics). 2. Genetic approach: mutagenize and see the phenotypic deviation, find the mutant, identify and clone the gene conferring that specific trait, predict ...
                        	... for the specific function; then clone the gene(s), mutate or knock them out (down) and demonstrate altered function (biochemistry+reverse genetics). 2. Genetic approach: mutagenize and see the phenotypic deviation, find the mutant, identify and clone the gene conferring that specific trait, predict ...
									Eukaryotic Gene Regulation
									
... genes for _____________________________. i. These proteins are found only in a specific cell type. ii. They give the cell its characteristic _______________ and function. iii. Many of these proteins are transcription factors, which bind to specific control elements in the enhancers of various target ...
                        	... genes for _____________________________. i. These proteins are found only in a specific cell type. ii. They give the cell its characteristic _______________ and function. iii. Many of these proteins are transcription factors, which bind to specific control elements in the enhancers of various target ...
									Gene Regulation in Eukaryotes Webquest
									
... these stuff genes on and off. The body-plan genes are what throw these switches, which tell the stuff genes what to do and when. This subtle choreography can have profound effects on how different animal bodies are formed. And this knowledge is helping us solve perhaps the biggest Darwinian puzzle o ...
                        	... these stuff genes on and off. The body-plan genes are what throw these switches, which tell the stuff genes what to do and when. This subtle choreography can have profound effects on how different animal bodies are formed. And this knowledge is helping us solve perhaps the biggest Darwinian puzzle o ...
									Overview of Articles for the literature talks Nr PMID Titel Date
									
... response. In this study, we address the dynamics of growth factor signaling through profiling of protein phosphorylation and gene expression, demonstrating the presence of a kinetically defined cluster of delayed early genes that function to attenuate the early events of growth factor signaling. Usi ...
                        	... response. In this study, we address the dynamics of growth factor signaling through profiling of protein phosphorylation and gene expression, demonstrating the presence of a kinetically defined cluster of delayed early genes that function to attenuate the early events of growth factor signaling. Usi ...
									LEGO PROTEIN SYNTHESIS (25 pts)
									
... As well as these 'specialized' proteins, almost all your cells share a common set of 'housekeeping' proteins. I know that you must be wondering……How do cells decide which proteins to make? Almost all your cells have the same set of genes (DNA). These carry instructions for making every protein in yo ...
                        	... As well as these 'specialized' proteins, almost all your cells share a common set of 'housekeeping' proteins. I know that you must be wondering……How do cells decide which proteins to make? Almost all your cells have the same set of genes (DNA). These carry instructions for making every protein in yo ...
									You and your Genes.
									
... • In the future, genetic modification could be used to treat or prevent genetic disease. • They could do this by putting normal alleles into the cells with the faulty alleles. • Genetic modification could also be used to make designer babies. • There are different ethical issues about this and many ...
                        	... • In the future, genetic modification could be used to treat or prevent genetic disease. • They could do this by putting normal alleles into the cells with the faulty alleles. • Genetic modification could also be used to make designer babies. • There are different ethical issues about this and many ...
									Immune System
									
... antibodies with unique constant region (IgE) Antigen binds to B cell and activates it Antigen binds to IgE on mast cells ...
                        	... antibodies with unique constant region (IgE) Antigen binds to B cell and activates it Antigen binds to IgE on mast cells ...
									MUTATIONS CAN OCCUR IN SOMATIC OR IN REPRODUCTIVE
									
... new nucleotide alters the codon affecting the sequence of amino acids and possible shape of functions of a protein ...
                        	... new nucleotide alters the codon affecting the sequence of amino acids and possible shape of functions of a protein ...
									DNA Chips
									
... transcribed into DNA & this DNA copy is integrated into host cell’s genome. - Integrated retrovirus’ genes transcribed & replicated like other chromosomal genes. - By inserting a cloned gene into a defective retrovirus vector, can get a cloned gene integrated into human cell’s genome, but can’t prod ...
                        	... transcribed into DNA & this DNA copy is integrated into host cell’s genome. - Integrated retrovirus’ genes transcribed & replicated like other chromosomal genes. - By inserting a cloned gene into a defective retrovirus vector, can get a cloned gene integrated into human cell’s genome, but can’t prod ...
									Paradigm Shifts in Biomedical Research
									
... and Cancer Checkpoints ensure that cells complete one event before proceeding to the next event Cancer is a disease of uncontrolled cell growth, sloppy DNA replication and errors in chromosome segregation ...
                        	... and Cancer Checkpoints ensure that cells complete one event before proceeding to the next event Cancer is a disease of uncontrolled cell growth, sloppy DNA replication and errors in chromosome segregation ...
									The Genetic Basis of Development
									
...  conservation of developmental genes in animals:  homeobox (180-nucleotide sequence) region found in homeotic genes & other developmental genes of many invertebrates and vertebrates is similar/identical  many developmental genes are highly conserved among species but may play different developmen ...
                        	...  conservation of developmental genes in animals:  homeobox (180-nucleotide sequence) region found in homeotic genes & other developmental genes of many invertebrates and vertebrates is similar/identical  many developmental genes are highly conserved among species but may play different developmen ...
									Ficha - temáticos
									
... have, for nearly two decades, regularly investigated the hereditary hemoglobinopathies present in the Brazilian population. The environment of the State University of Campinas facilitates this type of study, since in addition to laboratory investigations, including the analysis of proteins and nucle ...
                        	... have, for nearly two decades, regularly investigated the hereditary hemoglobinopathies present in the Brazilian population. The environment of the State University of Campinas facilitates this type of study, since in addition to laboratory investigations, including the analysis of proteins and nucle ...
									The Cell Recorded Lectures
									
... c. able to develop only into a few different types of cells Specialized d. not able to develop into any other types of cells 11. Describe four different times when a gene might be expressed or ‘turned on’. ...
                        	... c. able to develop only into a few different types of cells Specialized d. not able to develop into any other types of cells 11. Describe four different times when a gene might be expressed or ‘turned on’. ...
									FACULTY SPONSOR`S NAME AND DEGREE:
									
... that is, they are "immortal". Hence replicative senescence is a mechanism of protection against cancer. We have been studying human diploid fibroblasts (HF) to understand the mechanism of multi-step carcinogenesis ("transformation") of such cells in culture and its effect on cellular aging. We have ...
                        	... that is, they are "immortal". Hence replicative senescence is a mechanism of protection against cancer. We have been studying human diploid fibroblasts (HF) to understand the mechanism of multi-step carcinogenesis ("transformation") of such cells in culture and its effect on cellular aging. We have ...
									Airgas template
									
... One gene could mask the effect of another: epistasis/hypostasis One gene might depend on another: complementary Two genes together might create a new phenotype: collaborative A form of gene interaction whereby one gene masks or interferes with the phenotypic expression of one or more genes at other ...
                        	... One gene could mask the effect of another: epistasis/hypostasis One gene might depend on another: complementary Two genes together might create a new phenotype: collaborative A form of gene interaction whereby one gene masks or interferes with the phenotypic expression of one or more genes at other ...
									Non-Viral oncogene
									
... which converts PIPIII to PIPII because PIPIII will activate Pl-3/AKT which will activate BCL-2 that will inhibit apoptosis and induce cell transformation) ...
                        	... which converts PIPIII to PIPII because PIPIII will activate Pl-3/AKT which will activate BCL-2 that will inhibit apoptosis and induce cell transformation) ...
									GENETICS VOCABULARY STUDY GUIDE Chapter 2 – section 3 1
									
... 16. Having two different alleles for a trait. 17. Having two identical alleles for a trait. 18. An organism that has two different alleles for a trait. 19. The process that occurs in the formation of s ...
                        	... 16. Having two different alleles for a trait. 17. Having two identical alleles for a trait. 18. An organism that has two different alleles for a trait. 19. The process that occurs in the formation of s ...
									References - 기초의과학연구센터 MRC
									
... rearrangement was also affected by Apcdd1 knocking down. Further, we evaluated altered expression patterns of signaling molecules, related with EK, using RT-qPCR to understand the precise signaling regulations of Apcdd1. In addition, renal transplantation was employed to understand the detailed deve ...
                        	... rearrangement was also affected by Apcdd1 knocking down. Further, we evaluated altered expression patterns of signaling molecules, related with EK, using RT-qPCR to understand the precise signaling regulations of Apcdd1. In addition, renal transplantation was employed to understand the detailed deve ...
									Kolkata International School cum Conference on Systems Biology
									
... overcome these problems. Extracellular receptors and/or secreted growth factors that drive cancer metastasis make provocative targets as they are easily accessible on the cell surface and usually show high response rates at lower drug doses, resulting in negligible side effects. To discover novel can ...
                        	... overcome these problems. Extracellular receptors and/or secreted growth factors that drive cancer metastasis make provocative targets as they are easily accessible on the cell surface and usually show high response rates at lower drug doses, resulting in negligible side effects. To discover novel can ...
									Gene Section RASSF1 (Ras association (RalGDS/AF-6) domain family member 1)
									
... percentage in other tumors and indicate a role for this gene in malignant progression (62 % of bladder carcinoma; 49 % of breast tumors; 40 % of ovarian tumors; 12 % of colon cancer). ...
                        	... percentage in other tumors and indicate a role for this gene in malignant progression (62 % of bladder carcinoma; 49 % of breast tumors; 40 % of ovarian tumors; 12 % of colon cancer). ...
 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									 
									