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TIGAR: a promising new drug target for Parkinson`s research project
TIGAR: a promising new drug target for Parkinson`s research project

... Parkinson’s in great detail. Zebrafish with a faulty version of the PINK1 gene have problems with their energy-producing cell batteries (known as ‘mitochondria’) and slowly lose dopamine-producing nerve cells. ...
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... Despite your best efforts, and that of Michael Cummings, many students will confuse chromosome pairs with sister chromatids, sister chromatids with arms, and the events of meiosis I, meiosis II, and mitosis. Mitosis and meiosis are physical processes that must be studied visually for best results. O ...
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... protein-making machinery, called the ribosome, reads the mRNA sequence and translates it into the amino acid sequence of the protein. The ribosome starts at the sequence AUG, then reads 3 nucleotides at a time. Each 3-nucleotide codon specifies a particular amino acid. The “stop” codons (UAA, UAG, a ...
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... sequence of nucleotides, but they differ in at least one nucleotide in the sequence. Different alleles can result in different characteristics as follows: differences in the nucleotide sequence in the gene result in differences in the nucleotide sequence in mRNA result in differences in the amino ac ...
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... cell lines, was derived without consent in 1951 from Henrietta Lacks, who had cervical cancer. The cells and the way they were acquired have been the subject of controversy over the years. Last year, the HeLa genome was sequenced, rekindling ethics issues because the family had not consented to the ...
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... Copyright © 1995 by Academic Press, Inc. All rights of reproduction in any form reserved. ...
Prentice Hall Biology
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... • Recessive alleles – phenotype expressed in homozygous recessive individuals only. • Dominate alleles – phenotype expressed if the dominate allele is present (homozygous and heterozygous dominant). • Codominant alleles – both alleles are ...
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Leukaemia Section t(2;9)(p23;q33) TRAF1/ALK Atlas of Genetics and Cytogenetics in Oncology and Haematology

... with cytologic features of "hallmark" cells characteristic of ALCL. Immunohistochemical staining for CD30 shows strong positivity in the tumor cells, with a membranous and Golgi zone distribution. Staining for ALK shows strong cytoplasmic positivity without nuclear staining. The absence of nuclear s ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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