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MAGMA manual (version 1.05)
MAGMA manual (version 1.05)

... MAGMA detects a header in the file it will look for SNP IDs and p-values in the SNP and P column respectively. If no header is found it will use the first column for SNP IDs and the second column for p-values. If you want to use different columns instead, you can add the use modifier (with two value ...
METADOMAIN: A PROFILE HMM-BASED PROTEIN DOMAIN
METADOMAIN: A PROFILE HMM-BASED PROTEIN DOMAIN

... Low sensitivity of HMMER on classifying short reads. Because of the high sensitivity of remote homology recognition, HMMER has been successfully applied to genome-wide domain analysis. However, its sensitivity is significantly limited by the short reads of metagenomic data sets and poorly conserved d ...
LIST OF CHECK-UP QUESTIONS for
LIST OF CHECK-UP QUESTIONS for

... c) binary fission d) budding e) conjugation CORRECT f) schizogony 48. Each sperm consists of: a) a head region b) body or midpiece c) tail or flagellum. d) end piece e) all of these CORRECT 49. How many chromosomes are present in each spermatogonium, an oogonium? a) 46 CORRECT b) 23 c) 1600 d) 400 e ...
HW4_final
HW4_final

... 3. In a different study it has been shown that PUM2 binds RNA only in loop regions (single stranded) of the folded RNA which contain the consensus motif. The researcher is studying 5 RNA sequences in the 3’ untranslated regions of different genes (sequences are found below) and is interested to lear ...
Ret/PTC3 is the most frequent form of gene rearrangement
Ret/PTC3 is the most frequent form of gene rearrangement

... The inactivation of tumor suppressor genes and the activation of oncogenes play important roles in the carcinogenesis of a variety of solid tumors in humans (Nakamura 1993; Nakamura 1996), while chromosomal rearrangements that produce chimeric oncogenes are occasionally associated with hematologic m ...
CBSE XII BIO QS with key(2009-2015)
CBSE XII BIO QS with key(2009-2015)

... Seeds produced without fertilization are referred to as apomictic =1 Advantage: desired characters retained in offspring (progeny)/ no segregation of characters in offspring(progeny)/ assured seed production in absenceof pollinators=1(any other relevant advantage) Disadvantage: cannot control accumu ...
PDF
PDF

... is one cause of congenital primary aphakia (Fig. 2E,F) (Valleix et al., 2006). Human aphakia is a rare congenital eye disorder in which the lens is missing. In primary aphakia, lens formation does not take place and the secondary ocular defects, including a complete aplasia of the anterior segment o ...
The Drosophila Gene Disruption Project: Progress
The Drosophila Gene Disruption Project: Progress

... have been described (Thibault et al. 2004). These lines probably do not represent a completely random collection of insertions, because some lines disrupting major hotspots appear to have been culled by Exelixis. However, we found many cases where at least two lines bearing identical piggyBac insert ...
PDF
PDF

... larvae, whose polymorphic epidermal cells sequentially produce first larval, then pupal and finally adult structures (Riddiford, 1994), while internally growing imaginal discs, if any occur, give rise to appendages only, particularly the wings (Svacha, 1992). Seminal studies in Drosophila have defin ...
Phylogenetic ANOVA: The Expression Variance and
Phylogenetic ANOVA: The Expression Variance and

... additionally been parameterized in an evolutionary model allowing for constrained trait ...
Part
Part

... In a testcross involving F1 dihybrid flies, more parentaltype offspring were produced then the recombinat type offspeing. This indicates ...
The genetics of diabetes mellitus
The genetics of diabetes mellitus

... had evidence for linkage, with sibling pair disease concordance or discordance being strongly affected by allele sharing at the D15S107 locus 21. Evidence for this association also arises from other studies on 104 Caucasian families and 81 Danish families22,23. However, contradictory results were re ...
Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in
Parallel Genetic and Phenotypic Evolution of DNA Superhelicity in

... (Kar et al. 2005), and IHF (Arfin et al. 2000), have also been shown to be global regulators of gene transcription in bacteria. These proteins are expressed at various levels during the cell cycle, generating yet another level of interplay between environmental signals, DNA superhelicity, and global ...
Rapid and accurate cancer somatic mutation
Rapid and accurate cancer somatic mutation

... non-receptor kinase pathways, as well as additional oncogene and tumor suppressor pathways. The targeted diseases include all major cancer types. In addition, a collection of more than 900 pre-verified somatic mutation assays enables researchers to study single mutations or to customize the mutation ...
Archives of Microbiology
Archives of Microbiology

... IdentiWcation of nifH and vnfH sequences An investigation of nitrogenase and hydrogenase genes in A. azotica carried out by Southern blotting yielded two signals with a probe for nifH, possibly due to the presence of nifH and vnfH, and one signal each using a probe for the uptake hydrogenase gene hu ...
International Agency for Research on Cancer (IARC)
International Agency for Research on Cancer (IARC)

Light Quality–Dependent Nuclear Import of the Plant Photoreceptors
Light Quality–Dependent Nuclear Import of the Plant Photoreceptors

... showed that this fusion protein is imported into the nuclei, an observation that indicates the presence of a functional nuclear localization sequence (NLS) in the C-terminal region of Arabidopsis phyB. The photoreceptors that have been characterized thus far, namely, phyA, cryptochrome 1 (CRY1), and ...
Obligate phototrophy in cyanobacteria: more than a lack of sugar
Obligate phototrophy in cyanobacteria: more than a lack of sugar

... 3.1. Search for glcP homologous genes in various cyanobacteria The strains tested (Table 1) were chosen upon two criteria, their (in)capacity of heterotrophic growth on glucose and when known of glucose uptake, and a G+C content as close as possible to that of Synechocystis PCC6803 [15,16]. Total DN ...
Genetic Control of Root Hair Development in
Genetic Control of Root Hair Development in

... wall to yield to interna1 pressure. The elongation stage of root hair development is known to depend on growth at the root hair tip (Sievers and Schnepf, 1981).For tip growth to occur, new cell wall components need to be directed to, and deposited at, the tip of the growing tube. The mechanism respo ...
wsp Gene Sequences from the Wolbachia of Filarial Nematodes
wsp Gene Sequences from the Wolbachia of Filarial Nematodes

... and WSPintR from nematode Wolbachia were sequenced directly, and the sequences were aligned to the wsp gene available for arthropod Wolbachia. We also tried to align wsp to the gene sequences available for the major outer membrane proteins of Anaplasma, Ehrlichia, and Cowdria species. While alignmen ...
Foundations of Biology - Geoscience Research Institute
Foundations of Biology - Geoscience Research Institute

... The Key To Morgan’s Discovery The key to Morgan’s discovery was the observation that all the white-eyed individuals in the F2 generation were males  Without this vital data on the association of white eyes with being male, the gene for white eyes could have been seen as a simple recessive trait on ...
PowerPoint Presentation - No Slide Title
PowerPoint Presentation - No Slide Title

... • Static genetic information is stored in DNA • Genes are portions of DNA which are “transcribed” into mRNA • mRNA is “translated” by ribosomes into proteins • Proteins carry out the essential cellular functions: enzymatic, regulatory, structural Sanguinetti, 2011 ...
Identification of New Genes Involved in Meiosis by a Genetic Screen
Identification of New Genes Involved in Meiosis by a Genetic Screen

... CO products (Lynn, 2007) (Figure 2). ZMM proteins Zip1, Zip2, Zip3, Zip4, Msh4, Msh5, Mer3 and Spo16 co-localize on meiotic chromosomes, and each of the deletion mutants confers similar phenotype suggesting that this group of 8 proteins is functionally collaborative (Börner et al., 2004). zmm mutant ...
invited review
invited review

... values from 0.4 (SGLT1) to 2 mM (SGLT2 and SGLT3). For D-glucose the K0.5 values are 0.4, 2, and 6 mM, respectively. Although SGLT1 does not discriminate among ␣-MDG, glucose, and galactose, neither SGLT2 nor SGLT3 transports D-galactose efficiently (K0.5 ⬎ 20 mM). It appears the S1/S2 transporter i ...
Information for couples where one partner carries
Information for couples where one partner carries

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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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