- University of Bath Opus
... In this thesis I present a comprehensive analysis of sex-biased gene expression in the primate genome and show that there is a significant degree of similarity in sex-biased gene expression among neighbouring genes. Whether this clustering of genes with similar expression profiles is functional or i ...
... In this thesis I present a comprehensive analysis of sex-biased gene expression in the primate genome and show that there is a significant degree of similarity in sex-biased gene expression among neighbouring genes. Whether this clustering of genes with similar expression profiles is functional or i ...
Management Perspectives Polled or Scurred: Do You Know the
... Not at all unexpected, males, the scur gene is or untypical when a single dominant, meaning that trait becomes the focus scurs will be present if of intense breeding, other even only one copy of the genetic-related discovergene is present. ThereScurs are small, loose, horny growths in the ies happen ...
... Not at all unexpected, males, the scur gene is or untypical when a single dominant, meaning that trait becomes the focus scurs will be present if of intense breeding, other even only one copy of the genetic-related discovergene is present. ThereScurs are small, loose, horny growths in the ies happen ...
Inferring Host Gene Subnetworks Involved in Viral
... L), are actually key host factors involved in viral replication. The integer linear program used in our approach consists of an objective function and a set of constraints characterizing subnetworks that are deemed biologically interpretable. Due to functional redundancy in the host genome and the i ...
... L), are actually key host factors involved in viral replication. The integer linear program used in our approach consists of an objective function and a set of constraints characterizing subnetworks that are deemed biologically interpretable. Due to functional redundancy in the host genome and the i ...
Slide 1
... moderate and severe types of hemophilia people have to take more precautions like not being in crowded of a place. People with severe hemophilia quality of life is not the same as a normal person because there is always the worry and fear that something could happen and if bleeding did occur there i ...
... moderate and severe types of hemophilia people have to take more precautions like not being in crowded of a place. People with severe hemophilia quality of life is not the same as a normal person because there is always the worry and fear that something could happen and if bleeding did occur there i ...
Identification of Genetic and Epigenetic Risk Factors for Psoriasis
... with psoriasis (12 involved, 8 uninvolved) and 10 unaffected individuals. Involved skin differed from normal skin at 1,108 CpG sites at adjusted p-value < 0.05. Twelve of those CpG sites mapped to the epidermal differentiation complex close to genes that are highly up-regulated in psoriasis. Hierarc ...
... with psoriasis (12 involved, 8 uninvolved) and 10 unaffected individuals. Involved skin differed from normal skin at 1,108 CpG sites at adjusted p-value < 0.05. Twelve of those CpG sites mapped to the epidermal differentiation complex close to genes that are highly up-regulated in psoriasis. Hierarc ...
Natural Variation in Sensitivity to a Loss of Chloroplast Translation in
... 2009), and flowering time. Emphasis was placed on earlyflowering accessions to facilitate genetic analysis. A list of accessions tested is presented in Supplemental Table S1. Spectinomycin was chosen to inhibit chloroplast translation based on past work (Zubko and Day, 1998; Dudas et al., 2012), known ...
... 2009), and flowering time. Emphasis was placed on earlyflowering accessions to facilitate genetic analysis. A list of accessions tested is presented in Supplemental Table S1. Spectinomycin was chosen to inhibit chloroplast translation based on past work (Zubko and Day, 1998; Dudas et al., 2012), known ...
Premature stop codons involved in muscular dystrophies
... the major genetic diseases, though the frequency may be higher for some syndromes or in specific human populations. Aminoglycosides have long been known to affect translational accuracy. In particular, they promote nonsense mutation suppression in bacteria and yeast.1 These antibiotics interact with ...
... the major genetic diseases, though the frequency may be higher for some syndromes or in specific human populations. Aminoglycosides have long been known to affect translational accuracy. In particular, they promote nonsense mutation suppression in bacteria and yeast.1 These antibiotics interact with ...
Hox patterning of the vertebrate axial skeleton
... reason for the sensitivity of this portion of the rib cage to loss of Hox function and the apparent lack of colinearity in this region of the axial skeleton has not been clear. The accumulated genetic results from single Hox mutations do not present strong correlations with phenotypes from HomC loss ...
... reason for the sensitivity of this portion of the rib cage to loss of Hox function and the apparent lack of colinearity in this region of the axial skeleton has not been clear. The accumulated genetic results from single Hox mutations do not present strong correlations with phenotypes from HomC loss ...
A survey on computational methods for enhancer and
... and their target promoters is 124kb (Jin et al. 2013). All these flexibility in enhancer location makes them much harder to identify than some other types of sequence elements, such as promoters, which are right upstream of the target genes. Second, up to now, no single features or combinations of f ...
... and their target promoters is 124kb (Jin et al. 2013). All these flexibility in enhancer location makes them much harder to identify than some other types of sequence elements, such as promoters, which are right upstream of the target genes. Second, up to now, no single features or combinations of f ...
Biophysics 101 Genomics and Computational Biology
... Selection and characterization of amino acid substitutions at residues 237-240 of TEM-1 beta-lactamase with altered substrate specificity Selection strategy for site-directed mutagenesis based on altered beta-lactamase specificity. Site-directed mutagenesis of yeast eEF1A. Viable mutants with altere ...
... Selection and characterization of amino acid substitutions at residues 237-240 of TEM-1 beta-lactamase with altered substrate specificity Selection strategy for site-directed mutagenesis based on altered beta-lactamase specificity. Site-directed mutagenesis of yeast eEF1A. Viable mutants with altere ...
STAR Test Sample Questions Table of Contents Biology (End-of-course) Cell Biology
... A species of finch has been studied on one of the geographically isolated Galapagos Islands for many years. Since the island is small, the lineage of every bird for several generations is known. This allows a family tree of each bird to be developed. Some family groups have survived and others have ...
... A species of finch has been studied on one of the geographically isolated Galapagos Islands for many years. Since the island is small, the lineage of every bird for several generations is known. This allows a family tree of each bird to be developed. Some family groups have survived and others have ...
Linkage, Recombination, and the Mapping of Genes on Chromosomes
... meiotic recombination generally reflects the physical distance between them; recombination data thus make it possible to determine the distance between genes along chromosomes. • Mitotic recombination: Rarely, recombination occurs during mitosis. In multicellular organisms, mitotic recombination can ...
... meiotic recombination generally reflects the physical distance between them; recombination data thus make it possible to determine the distance between genes along chromosomes. • Mitotic recombination: Rarely, recombination occurs during mitosis. In multicellular organisms, mitotic recombination can ...
Adult Learners Presentation
... As we age, elastin fibers lose much of their resilience and elastin production within the fibroblasts decreases. This overall decline in healthy elastin levels results in areas of decreased firmness, especially along the jaw line, neck, and around the eyes. ...
... As we age, elastin fibers lose much of their resilience and elastin production within the fibroblasts decreases. This overall decline in healthy elastin levels results in areas of decreased firmness, especially along the jaw line, neck, and around the eyes. ...
Full-Text PDF
... amino acid metabolism, assembly of Fe/S clusters and gluconeogenesis. They also control stress responses, in particular the oxidative stress response via reactive oxygen species (ROS) and calcium Ca2+ storage (rewiewed in [1] and references therein). They play a central role in aging [2] and are sub ...
... amino acid metabolism, assembly of Fe/S clusters and gluconeogenesis. They also control stress responses, in particular the oxidative stress response via reactive oxygen species (ROS) and calcium Ca2+ storage (rewiewed in [1] and references therein). They play a central role in aging [2] and are sub ...
Castric et al. (MBE 2010) - GEPV
... recombination among allelic lines with low versus High sequence divergence, whereas only cases of the latter are typically found when comparing functionally distinct SI specificities. In contrast to gametophytic SI, sporophytic SI allows the spontaneous generation of homozygote genotypes for a given ...
... recombination among allelic lines with low versus High sequence divergence, whereas only cases of the latter are typically found when comparing functionally distinct SI specificities. In contrast to gametophytic SI, sporophytic SI allows the spontaneous generation of homozygote genotypes for a given ...
sidecar pollen, an Arabidopsis thaliana male
... species (such as Arabidopsis and maize) this mitosis takes place before pollen is released from anthers. Mature Arabidopsis pollen therefore contains three cells – one vegetative cell and two sperm cells enclosed within the cytoplasm of the vegetative cell. Pollen offers an excellent system with whi ...
... species (such as Arabidopsis and maize) this mitosis takes place before pollen is released from anthers. Mature Arabidopsis pollen therefore contains three cells – one vegetative cell and two sperm cells enclosed within the cytoplasm of the vegetative cell. Pollen offers an excellent system with whi ...
Feline Genetics: a Combinatorial Approach - MTMK-ICF
... effect which piles up with the others, yielding a more gradual combined result than a unique gene could account for. Sometimes we shall present two alternative mathematical models to explain the same effect. If the two models give the same effect in all cases, they are mathematically equivalent, alt ...
... effect which piles up with the others, yielding a more gradual combined result than a unique gene could account for. Sometimes we shall present two alternative mathematical models to explain the same effect. If the two models give the same effect in all cases, they are mathematically equivalent, alt ...
Comm function at the CNS midline - Development
... functional Robo levels silences the attractive response by commissural neurones to the midline cue netrin (Shirasaki et al., 1998; Stein and Tessier-Lavigne, 2001) through a direct interaction between Robo and DCC. Thus, regulation of Robo protein levels is crucial for correct axonal migration at th ...
... functional Robo levels silences the attractive response by commissural neurones to the midline cue netrin (Shirasaki et al., 1998; Stein and Tessier-Lavigne, 2001) through a direct interaction between Robo and DCC. Thus, regulation of Robo protein levels is crucial for correct axonal migration at th ...
NIH Public Access
... The inactivation of one X chromosome in mammalian females is a powerful model for epigenetic regulation in early development, involving formation of facultative heterochromatin that sweeps across an entire chromosome. Remarkably, a large non-coding RNA from the X-linked human XIST/mouse Xist gene (B ...
... The inactivation of one X chromosome in mammalian females is a powerful model for epigenetic regulation in early development, involving formation of facultative heterochromatin that sweeps across an entire chromosome. Remarkably, a large non-coding RNA from the X-linked human XIST/mouse Xist gene (B ...
Journal of Bacteriology
... with the Foscm-TCF and Foscm-TCR primers bearing 70-bp side arms that bind to the flanking regions of the cat gene of pCC1fos. For inactivation of the pmxE gene, a chloramphenicol resistance gene-kanamycin resistance gene (cat-kan) cassette was introduced into the pmxE structural gene of pPmx-Tc usi ...
... with the Foscm-TCF and Foscm-TCR primers bearing 70-bp side arms that bind to the flanking regions of the cat gene of pCC1fos. For inactivation of the pmxE gene, a chloramphenicol resistance gene-kanamycin resistance gene (cat-kan) cassette was introduced into the pmxE structural gene of pPmx-Tc usi ...
How Do Fibers Form?
... f. To complete the model, place a second circle over the top of the first circle and stretch it to the same shape. If you don’t have to stretch it, leave it as is. Trace around the RBC to record its shape. Is the shape of the model RBC containing oxyhemoglobin A normal or sickled? _________ 4. Now m ...
... f. To complete the model, place a second circle over the top of the first circle and stretch it to the same shape. If you don’t have to stretch it, leave it as is. Trace around the RBC to record its shape. Is the shape of the model RBC containing oxyhemoglobin A normal or sickled? _________ 4. Now m ...
Full Text
... blot analysis revealed that the number of double heterozygous weanlings was significantly reduced below the number expected based on the additive effects predicted from the observed losses due to heterozygosity at the individual loci (Table 1). Incompletely penetrant heterozygous defects have been r ...
... blot analysis revealed that the number of double heterozygous weanlings was significantly reduced below the number expected based on the additive effects predicted from the observed losses due to heterozygosity at the individual loci (Table 1). Incompletely penetrant heterozygous defects have been r ...
Evolution of Closely Linked Gene Pairs in
... pairs was determined, together with the length of the intergenic region, by means of python scripting on the Ensembl gene annotation files in Ensmart (script available from the authors). The intergenic region was defined as the number of base pairs between the beginning and/or ends of the transcript ...
... pairs was determined, together with the length of the intergenic region, by means of python scripting on the Ensembl gene annotation files in Ensmart (script available from the authors). The intergenic region was defined as the number of base pairs between the beginning and/or ends of the transcript ...
Role of tumor necrosis factor alpha gene polymorphism in childhood
... in 50 asthmatic children, 50 wheezy infants and 50 control school children. Genotype frequencies for the TNF-a 308 G/A OR were significantly more in asthmatic children from controls OR 0.4 95%CI (0.1 – 1.9) p <0.001 also a significantly higher frequency of the GA polymorphism in wheezy infant compar ...
... in 50 asthmatic children, 50 wheezy infants and 50 control school children. Genotype frequencies for the TNF-a 308 G/A OR were significantly more in asthmatic children from controls OR 0.4 95%CI (0.1 – 1.9) p <0.001 also a significantly higher frequency of the GA polymorphism in wheezy infant compar ...