Synonymous codon bias and functional constraint on GC3
... The highly non-random organization of codon assignment with respect to mutational impact on protein hydrophobicity is now a widely accepted evidence for an ancient history of purifying selection acting on various genetic coding schemes (19,20) and thus supporting a view that the code is a fixed or ‘ ...
... The highly non-random organization of codon assignment with respect to mutational impact on protein hydrophobicity is now a widely accepted evidence for an ancient history of purifying selection acting on various genetic coding schemes (19,20) and thus supporting a view that the code is a fixed or ‘ ...
Poster
... facilitates alternative splicing. This protein has a RRM (RNA recognition motif) that provides the first example of binding specific RNA guanines (Gs) through amino acids in three loops. Classical RRMs bind RNA through their beta-sheet surfaces. New research also suggests that over expression of hnR ...
... facilitates alternative splicing. This protein has a RRM (RNA recognition motif) that provides the first example of binding specific RNA guanines (Gs) through amino acids in three loops. Classical RRMs bind RNA through their beta-sheet surfaces. New research also suggests that over expression of hnR ...
Radiation-Sensitivity and Transcription Profiles in
... individualization of radiation treatment. Radiation-induced transcriptional responses have been studied using DNA microarray (Kis et al. 2006; Jen and Cheung, 2006). Some previous studies have also examined cells harboring mutant p53 using DNA microarray (Amandson et al. 2003; Scian et al. 2004), bu ...
... individualization of radiation treatment. Radiation-induced transcriptional responses have been studied using DNA microarray (Kis et al. 2006; Jen and Cheung, 2006). Some previous studies have also examined cells harboring mutant p53 using DNA microarray (Amandson et al. 2003; Scian et al. 2004), bu ...
Significant enhancement of fatty acid composition in seeds of the
... carried various Cas9 and sgRNA genes targeting FAD2 genes were generated and analysed during this study (Data Set S1). From these T1 plants, we produced large numbers of T2 and T3 plant progeny and seeds (Data Set S1) and limited samples of T4 seeds. Each plant generated in this study was given a un ...
... carried various Cas9 and sgRNA genes targeting FAD2 genes were generated and analysed during this study (Data Set S1). From these T1 plants, we produced large numbers of T2 and T3 plant progeny and seeds (Data Set S1) and limited samples of T4 seeds. Each plant generated in this study was given a un ...
Role of Clock Gene period
... Biological Clock -Mutants that lack functional period are arrhythmic. ...
... Biological Clock -Mutants that lack functional period are arrhythmic. ...
Accounting for Non-Genetic Factors Improves the Power of eQTL
... 11.4 which is not statistically significant. Also for computational reasons, we apply maximum likelihood methods to estimate the parameters θ, rather than the variational approach which is Bayesian but much more expensive. Because maximum likelihood methods perform poorly with little data, we remove ...
... 11.4 which is not statistically significant. Also for computational reasons, we apply maximum likelihood methods to estimate the parameters θ, rather than the variational approach which is Bayesian but much more expensive. Because maximum likelihood methods perform poorly with little data, we remove ...
telomeres - Atlas of Genetics and Cytogenetics in Oncology and
... TRF2-negative telomeres are recognized as damaged DNA Negative regulator of telomere length; TRF2 overexpression in somatic cells = telomere shortening TRF2 inhibition causes apoptosis and non-homologous end joining (NHEJ) of telomeres Promotes binding of hRAP1, a telomere associated protein ...
... TRF2-negative telomeres are recognized as damaged DNA Negative regulator of telomere length; TRF2 overexpression in somatic cells = telomere shortening TRF2 inhibition causes apoptosis and non-homologous end joining (NHEJ) of telomeres Promotes binding of hRAP1, a telomere associated protein ...
Transgenic Tobacco Plants Expressing the Drosophila
... needlelike phenotypes failed to produce a leaf blade, although midrib-specific cells were unaltered (Figure 6B), and that those with broad-leaf phenotypes showed some characteristic alterations in the blade. In comparison to wild-type tissue (Figures 6A and 6C), the numbers of cells per area was red ...
... needlelike phenotypes failed to produce a leaf blade, although midrib-specific cells were unaltered (Figure 6B), and that those with broad-leaf phenotypes showed some characteristic alterations in the blade. In comparison to wild-type tissue (Figures 6A and 6C), the numbers of cells per area was red ...
5. Harmful mutations
... UV light mostly damages DNA by producing thymine dimers, which are cross-links between adjacent pyrimidine bases in a DNA strand. On the other hand, oxidants such as free radicals or hydrogen peroxide produce multiple forms of damage, including base modifications, particularly of guanosine, as well ...
... UV light mostly damages DNA by producing thymine dimers, which are cross-links between adjacent pyrimidine bases in a DNA strand. On the other hand, oxidants such as free radicals or hydrogen peroxide produce multiple forms of damage, including base modifications, particularly of guanosine, as well ...
RESEARCH ARTICLE Mutational Analysis of Prohibitin
... was first linked to human cancers by the discoveries of prohibitin mutations in breast cancers (Sato et al., 1993). Since, the initial report by Sato et al. (1992; 1993), four mutations were reported in total of 23 breast cancer patients, it gained the attention of researchers to investigate its pos ...
... was first linked to human cancers by the discoveries of prohibitin mutations in breast cancers (Sato et al., 1993). Since, the initial report by Sato et al. (1992; 1993), four mutations were reported in total of 23 breast cancer patients, it gained the attention of researchers to investigate its pos ...
Biology
... Francis Crick built a model that explained how DNA carried information and could be copied. Watson and Crick's model of DNA was a double helix, in which two strands were wound around each other. ...
... Francis Crick built a model that explained how DNA carried information and could be copied. Watson and Crick's model of DNA was a double helix, in which two strands were wound around each other. ...
Accompanying Powerpoint Presentation
... monotherapy after failure of fluoropyrimidine, oxaliplatin and irinotecan-containing chemotherapy regimens. ...
... monotherapy after failure of fluoropyrimidine, oxaliplatin and irinotecan-containing chemotherapy regimens. ...
Leukaemia Section t(5;12)(q33;p13) ERC1/PDGFRB Atlas of Genetics and Cytogenetics
... Membrane receptor that binds specifically to PDGFB and has a tyrosine-protein kinase activity. Signal transduction. ...
... Membrane receptor that binds specifically to PDGFB and has a tyrosine-protein kinase activity. Signal transduction. ...
screening for genes involved in pathogenesis
... attenuated in virulence on walnut (Figure 1) indicating that genes regulated by this locus are important in these phenotypes. Bacterial polymerases require the transient association of proteins called sigma factors for the initiation of transcription. Various sigma factors confer different specific ...
... attenuated in virulence on walnut (Figure 1) indicating that genes regulated by this locus are important in these phenotypes. Bacterial polymerases require the transient association of proteins called sigma factors for the initiation of transcription. Various sigma factors confer different specific ...
Communique of GTTAC Meeting 18 September 2003 and 28
... Roundup Ready cotton in that it contains two copies of the cp4 epsps gene that provides tolerance to glyphosate (the active ingredient in the herbicide Roundup®). The applicant anticipates that this will enable Roundup to be applied to control weeds over a longer period of plant growth, giving gro ...
... Roundup Ready cotton in that it contains two copies of the cp4 epsps gene that provides tolerance to glyphosate (the active ingredient in the herbicide Roundup®). The applicant anticipates that this will enable Roundup to be applied to control weeds over a longer period of plant growth, giving gro ...
Document
... This experiment of George Shull demonstrates an important phenomenon, confirmed in subsequent genetic studies. Many eukaryotic genes appear to be redundant. In other words, there are two (or more) genes that can play analogous roles in the life of the organism. In this example, either of the domina ...
... This experiment of George Shull demonstrates an important phenomenon, confirmed in subsequent genetic studies. Many eukaryotic genes appear to be redundant. In other words, there are two (or more) genes that can play analogous roles in the life of the organism. In this example, either of the domina ...
Bioinformatics Exercises Over the last two decades, information has
... Chapter 3 is an introduction to nucleotides, nucleic acids (DNA and RNA), and the processes of transcription and translation. Finding Databases. One of the major bioinformatics tools is the biological database. These databases are an important resource for the study of biochemistry at all levels. Th ...
... Chapter 3 is an introduction to nucleotides, nucleic acids (DNA and RNA), and the processes of transcription and translation. Finding Databases. One of the major bioinformatics tools is the biological database. These databases are an important resource for the study of biochemistry at all levels. Th ...
S1.Coat color in rodents is determined by a gene interaction
... This experiment of George Shull demonstrates an important phenomenon, confirmed in subsequent genetic studies. Many eukaryotic genes appear to be redundant. In other words, there are two (or more) genes that can play analogous roles in the life of the organism. In this example, either of the domina ...
... This experiment of George Shull demonstrates an important phenomenon, confirmed in subsequent genetic studies. Many eukaryotic genes appear to be redundant. In other words, there are two (or more) genes that can play analogous roles in the life of the organism. In this example, either of the domina ...
ECA Biology Review 1 1. Which three elements are often found in
... protein, E-cadherin, is ‘glue’ that keeps cells together in the body—without it we would not develop beyond a bundle of cells a few days after conception, said Dr. Chris Ward, who led the study in the University’s School of Dentistry. “E—cadherin is also important during cancer progression from beni ...
... protein, E-cadherin, is ‘glue’ that keeps cells together in the body—without it we would not develop beyond a bundle of cells a few days after conception, said Dr. Chris Ward, who led the study in the University’s School of Dentistry. “E—cadherin is also important during cancer progression from beni ...
How Biologists Conceptualize Genes: An empirical study
... unit. This has led to definitions of the gene, which include the promoter and regulatory sequences that affect whether the gene will be transcribed. In a case like the famous lac operon in E. coli, these sites are immediately upstream of the site at which transcription is initiated and it is easy to ...
... unit. This has led to definitions of the gene, which include the promoter and regulatory sequences that affect whether the gene will be transcribed. In a case like the famous lac operon in E. coli, these sites are immediately upstream of the site at which transcription is initiated and it is easy to ...
Communique of GTTAC Meeting 18 September 2003 and 28
... Recombinant adenovirus and adenovirus-associated viruses carrying Hepatitis C virus (HCV) genes will be used to produce HCV proteins in cell cultures and mice to study the structure and function of the proteins as well produce HCV protein for immune studies. ...
... Recombinant adenovirus and adenovirus-associated viruses carrying Hepatitis C virus (HCV) genes will be used to produce HCV proteins in cell cultures and mice to study the structure and function of the proteins as well produce HCV protein for immune studies. ...