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Dairy cattle reproduction is a tightly regulated genetic process
Dairy cattle reproduction is a tightly regulated genetic process

... (Feugang et al., 2010). Semen from high-fertility bulls contained higher concentrations of mRNA coding for transporters and translational factors while genes involved in transcription, protein binding, and cell cycle were upregulated in low-fertility bulls. Thus, a great proportion of differentially ...
08.seg_dup_els - NYU Computer Science
08.seg_dup_els - NYU Computer Science

... sequences, or transposable elements and their relics). However, other studies ...
Redalyc.Prevalence of ΔF508 mutation in the cystic fibrosis
Redalyc.Prevalence of ΔF508 mutation in the cystic fibrosis

... is negative for this mutation, molecular analysis becomes complex due to the high number of existing mutations in the CFTR gene. The molecular characterization of the disease enables genetic counseling and appropriate pulmonary surveillance, which may become even more important as therapeutic ...
Biotechnology Explorer™ Ligation and Transformation - Bio-Rad
Biotechnology Explorer™ Ligation and Transformation - Bio-Rad

... • Screening — When bacteria are being transformed with a ligation reaction, not all of the religated vectors will necessarily contain the DNA fragment of interest. To produce visible indicators that cells contain an insert, vectors frequently contain reporter genes, which distinguish them from cell ...
Pedigree Questions from VCAA Exams with answers
Pedigree Questions from VCAA Exams with answers

... *To be awarded full marks, the answer needed to have a piece of evidence for dominance and a piece of evidence for autosomal. (1 + 2 = 3 marks) 36% of people got 0, 17% got 1, 25% got 2, 21% got 3. ...
CHAPTER 15 THE CHROMOSOMAL BASIS OF INHERITANCE
CHAPTER 15 THE CHROMOSOMAL BASIS OF INHERITANCE

... • The crossover data allowed them to cluster the known mutations into four major linkage groups. • Since Drosophila has four sets of chromosomes, this clustering of genes into four linkage groups was further evidence that genes are on chromosomes. Maps based on crossover data only give information a ...
biology - LearnCOACH
biology - LearnCOACH

... the number of chromosomes • The male and female gametes with half the number of chromosomes combine to give a zygote (fertilized egg) with the full number of chromosomes • Gamete – male and female sex cells; the sperm and eggs • Zygote – The resulting one-celled organism, after a female egg is fe ...
The Mycobacterium tuberculosis katG promoter region contains a
The Mycobacterium tuberculosis katG promoter region contains a

... with these show similarity to previously identified mycobacterial promoters. Deletions in the promoter fragment, introduced with BAL-31 nuclease and restriction endonucleases, revealed that a region between 559 and 448 bp upstream of the translation initiation codon, designated the upstream activato ...
Microsatellite Polymorphism in the Heme Oxygenase
Microsatellite Polymorphism in the Heme Oxygenase

... SUMMARY: Cerebral malaria (CM) is a serious complication of Plasmodium falciparum malaria, and its pathogenesis leading to coma remains unknown. Heme oxygenase-1 (HO-1) catalyzes heme breakdown, eventually generating bilirubin, iron and carbon monoxide. The HO-1 gene promoter contains a polymorphic ...
Commercialization of a Protein Product from Transgenic Maize
Commercialization of a Protein Product from Transgenic Maize

... of codons that are common to the host plant can enhance the translatability of the messenger RNA. From experience, the leading amino acids appear to be the most critical in this regard, presumably because they initiate efficient translation. In the case of bovine trypsin, the native Bos taurus gene ...
Using Ontology Graphs to Understand Annotations and Reason about Them
Using Ontology Graphs to Understand Annotations and Reason about Them

... particular mouse models (phenotypes) reveal the contribution of particular genomic variants (alleles) to the presentation of disease phenotypes. The annotation of genotype-phenotype associations is an essential part of assessing mouse models for human disease. ...
Maintenance of DNA Methylation during the Arabidopsis Life Cycle
Maintenance of DNA Methylation during the Arabidopsis Life Cycle

... depends directly or indirectly on MET1. DNA methylation is propagated through replication in a semiconservative manner (Finnegan et al., 2000). Because in the MET1as line MET1 antisense RNAs are produced only during vegetative development, we propose that demethylation of FIS2 during vegetative deve ...
HbF inducers
HbF inducers

... Other compounds ● Thalidomide, Lenalidomide and pomalidomide are other components that induces increased expression of the γ-globin gene and HbF production ● when combined with hydroxyurea, pomalidomide and, to a lesser extent, lenalidomide were found to have synergistic effects on HbF up-regulatio ...
SEARCH_16S: A new algorithm for identifying 16S
SEARCH_16S: A new algorithm for identifying 16S

... Of the 6,487 finished assemblies, 6,401 had feature tables provided by NCBI. SEARCH_16S and NCBI reported the same number of 16S genes (i.e., number of paralogs) in 5,724 (88%). A total of 26,816 genes were reported with 24,402 (91%) reported by both. A gene was considered to be reported by both met ...
Genetics and Pedigrees Bio I
Genetics and Pedigrees Bio I

... Gregor Mendel ...
Friedreich ataxia: The clinical picture
Friedreich ataxia: The clinical picture

... dystrophy, and differs from diseases that result from CAG repeats in coding regions, such as the dominant ataxias and Huntington disease, in which further expansion typically occurs after paternal transmission. The GAA expansion is also unstable in somatic cells, including post-mitotic cells [26]. I ...
Replicational and transcriptional selection on codon usage in
Replicational and transcriptional selection on codon usage in

... level of replication. An organism that can replicate more quickly could have a selective advantage over one whose replication is retarded. It was pointed out by Fraser et al. (7) that approximately two-thirds of the genes on the B. burgdorferi genome were transcribed away from the origin of replicat ...
Genetic Inversion: Relationships Among Species
Genetic Inversion: Relationships Among Species

... the most important events occur in sex cells (sperm or egg cells). These changes exhibit their full effect on any offspring formed from these inverted sperm or egg chromosomes. In other words, an inversion that occurs in a skin cell only affects that skin cell and its descendants, but the other tril ...
FOXP2: the language gene
FOXP2: the language gene

... • The human-specific change at position 325 creates a potential target site for phosphorylation by protein kinase C together with a minor change in predicted secondary structure. ...
Causes, consequences and solutions of
Causes, consequences and solutions of

... The widespread occurrences of phylogenetic incongruence among methods and also among genes are well-known [10, 11]. Although there is no doubt about the existence of statistically significant incongruence among different tree reconstruction methods, but statistically significant incongruence among g ...
Molecular markers located on the DGAT1, CAST, and - Funpec-RP
Molecular markers located on the DGAT1, CAST, and - Funpec-RP

... (Butler and Smith, 1989; Washburn et al., 2002), and modern Holstein cattle are now producing significantly more milk than in previous decades. The lactation cycle is initiated and renewed by parturition; therefore, an animal must have the ability to conceive, maintain a pregnancy, and rebreed in a ...
University of Bucharest, Faculty of Biology, Molecular Biology Center
University of Bucharest, Faculty of Biology, Molecular Biology Center

... For this study we have used blood samples from 90 Romanian Black Spotted cattle (ICDB Baloteşti farm). White cells from fresh blood sample (300 µl) were preserved in EDTA anticoagulant, and were hypotonically lysed. The isolation of genomic DNA was performed with Wizard Genomic DNA Extraction Kit (P ...
MER3 is required for normal meiotic crossover formation, but not for
MER3 is required for normal meiotic crossover formation, but not for

... Intriguingly, the frequency of class I and II COs vary in different organisms. Recently, the Arabidopsis homologs of MSH4, MSH5, MER3 and ZIP4 were investigated. All the mutants of these genes show a dramatic reduction of COs. In addition, the remaining COs are processed in a pathway that is not sub ...
Origin of the eukaryotic cell
Origin of the eukaryotic cell

... The discovery of 2.1 billion years old Eukaryotic fossils in Gabon July 2010 has brought new insights into the origin of eukaryotic cell (Albani et al. 2010). The relationship among three domains, Eukaryotes, Bacteria and Archaea, in the tree of life was investigated in this project through phylogen ...
Spider Silk - Consortium for Mathematics and its Applications
Spider Silk - Consortium for Mathematics and its Applications

... synthesize these proteins for us. Scientists do this by building a DNA sequence that codes for the desired protein sequence. The ability to build this sequence is a technological achievement of no small note. They then insert the sequence into the genome of some bacteria such as E. coli (another maj ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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