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Beads on a string Bowater Biochem Soc Trans 2012
Beads on a string Bowater Biochem Soc Trans 2012

... between adjacent nucleosomes. The data from the Richmond laboratory provide support for ATP-dependent remodelling factors as the important driver of nucleosome positioning. The location of nucleosomes on genomic DNA is affected by active transcription and replication. Ozgen Deniz [9] described the r ...
DNA cloning
DNA cloning

... mRNA by reverse transcription are inserted into a vector to form a cDNA library. Much more efficient in identifying a gene, but yield only the coding region, and not surrounding genomic sequence. ...
14–16 Video transcript: Chickens and Campylobacter
14–16 Video transcript: Chickens and Campylobacter

... So then we start off doing a PCR reaction, where we use primers to target the part of the gene that we're interested in. Actually, for this technique we're using parts of seven genes, and the combination of that, once we've got the DNA sequenced, is, in effect, like a shop barcode. And it's a way of ...
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Homologous chromosome

... SOURCE: BIOLOGY: CONCEPTS AND CONNECTIONS BY CAMPBELL, REECE, MITCHELL, TAYLOR ...
ch 12 quick check answers
ch 12 quick check answers

... True: DNA profiles based on chromosomal DNA give far more precise identification than that obtained using mitochondrial DNA (mtDNA). This occurs because mtDNA is inherited generation after generation without recombination from maternal ancestors, while STRs undergo reassortment during meiosis at eve ...
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... Pitfalls and Issues 4) Very short exons: some exons are only 3 bp long in Arabidopsis genes and probably even 1 bp for the coding part of exons at either end of the coding sequence, meaning that start or stop codons can be interrupted by an intron. Such small exons are easily missed by all content ...
BDOL Interactive Chalkboard
BDOL Interactive Chalkboard

... • The DNA of people with and without a genetic disorder is compared to find differences that are associated with the disorder. Once it is clearly understood where a gene is located and that a ____________ in the gene causes the disorder, a diagnosis can be made for an individual, even before birth. ...
Bio II Ch 19 Eukaryotic Genomes
Bio II Ch 19 Eukaryotic Genomes

... Copyright © 2002 Pearson Education, Inc., publishing as Benjamin Cummings ...
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Chapter 1 - bYTEBoss

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Supplementary methods RNA FISH probe specificity analysis. For

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... The nucleus is the library, the DNA/chromosomes are the reference books that cannot leave the library, and the mRNA is the transcription or copy of a small part of the DNA, a gene, that is slipped through the nuclear pore to a ribosome (rRNA + proteins) in the cytosol that will be involved in transl ...
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...  The sections are the same as in a prokaryotic entry  SOURCE contains a map section that indicates the chromosome containing the gene  GENE introduces indications to reconstruct the CDS from the gene  Remember: Eukaryotic genes are interrupted by introns ...
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Introduction to Microarray Analysis (Section D1)

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chapter 18 microbial models: the genetics of viruses and bacteria

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GMO Investigator™ Kit - Bio-Rad

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Chromosomal insertion of foreign DNA

... Summary ― The main route and, in most species, the only reliable route to the generation of transgenic animals is by microinjecting DNA into an early embryo, generally one of the pronuclei of a newly fertilized egg (a one-cell embryo). In most cases, a small number (perhaps 100) of identical ...
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P1 The genetic code

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Microarray Services
Microarray Services

Science League Biology I Exam January 2014 Choose the answer
Science League Biology I Exam January 2014 Choose the answer

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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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