Analysis of Flanking Sequences from Dissociation
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
Analysis of Flanking Sequences from Dissociation
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
... 1996a, 1996b). Each NOR occupies 3.5 to 4.0 Mb and consists of tandemly repeated rRNA gene clusters. The nucleolus is organized around the NORs during interphase and is associated with very active transcription of ribosomal genes by RNA polymerase I. The increasing frequency of insertions into the N ...
Full-text PDF
... Let us now consider an example. It has long been hypothesized that there may be some kind of correspondence between gene transcription order and functional relationships of the encoded proteins. Dandekar et al. showed that some highly conserved gene pairs do indeed interact physically on the same me ...
... Let us now consider an example. It has long been hypothesized that there may be some kind of correspondence between gene transcription order and functional relationships of the encoded proteins. Dandekar et al. showed that some highly conserved gene pairs do indeed interact physically on the same me ...
Additional File 1
... Supplemental Figure S3. Performance on matching simulated test sets using RIDDLE, components of RIDDLE (forward and reverse LE, RD-AUC, RD-AP, and HG), known set size, overlap, and known set average centrality, and previously established global-network method, GsNetCom. GsNetCom performs well for ...
... Supplemental Figure S3. Performance on matching simulated test sets using RIDDLE, components of RIDDLE (forward and reverse LE, RD-AUC, RD-AP, and HG), known set size, overlap, and known set average centrality, and previously established global-network method, GsNetCom. GsNetCom performs well for ...
Zoo/Bot 3333
... a) 2.5 map units; b) 5 map units; c) 10 map units; d) 15 map units; e) can't be calculated from this data set, since the genes are farther than 50 map units apart or are on separate chromosomes. ...
... a) 2.5 map units; b) 5 map units; c) 10 map units; d) 15 map units; e) can't be calculated from this data set, since the genes are farther than 50 map units apart or are on separate chromosomes. ...
Gene - CS273a
... sites, preventing/repelling the binding of – The RNA polymerase machinery – Activating transcription factors (including via competitive binding) • Some transcription factors have stereotypical roles as activators or repressors. Likely many can do both (in different contexts). • DNA can be bent into ...
... sites, preventing/repelling the binding of – The RNA polymerase machinery – Activating transcription factors (including via competitive binding) • Some transcription factors have stereotypical roles as activators or repressors. Likely many can do both (in different contexts). • DNA can be bent into ...
Gene therapy: Current status and future perspectives
... reverse transcriptase which can create double- stranded DNA copies of their RNA genomes. These copies of its genome can be integrated into the chromosome of host cell. Although retroviruses have been used in most gene therapy experiments, there are some drawbacks. The main limitations of retroviral ...
... reverse transcriptase which can create double- stranded DNA copies of their RNA genomes. These copies of its genome can be integrated into the chromosome of host cell. Although retroviruses have been used in most gene therapy experiments, there are some drawbacks. The main limitations of retroviral ...
Inheritance
... Dickens Moment (Dominant and recessive genes) One day in the ag room, the two brothers Dominant and Recessive Gene walked in. They were arguing with each other as usual. Recessive was upset with Dominant because he is the one that is always noticed. Recessive is tired of living in Dominant’s shadow ...
... Dickens Moment (Dominant and recessive genes) One day in the ag room, the two brothers Dominant and Recessive Gene walked in. They were arguing with each other as usual. Recessive was upset with Dominant because he is the one that is always noticed. Recessive is tired of living in Dominant’s shadow ...
Table S3 - BioMed Central
... ChEMBL, and etc). This index allows filtering Drug2Gene for the subset of information coming only from a subset of primary resources. Gives you the possibility to search e.g. ChEMBL content to provide Drug2Gene functionality which ChEMBL does not provide. ...
... ChEMBL, and etc). This index allows filtering Drug2Gene for the subset of information coming only from a subset of primary resources. Gives you the possibility to search e.g. ChEMBL content to provide Drug2Gene functionality which ChEMBL does not provide. ...
The Detection of Carbapenemases in Carbapenem
... We collected 100 isolates of MDRGN bacteria from patients admitted to UMMC from April through September 2014. We identified and performed susceptibilities by Vitek II (BioMerieux, Durham, NC) or disk diffusion method following CLSI guidelines. Isolates were tested using the Acuitas® MDRO Gene Test ( ...
... We collected 100 isolates of MDRGN bacteria from patients admitted to UMMC from April through September 2014. We identified and performed susceptibilities by Vitek II (BioMerieux, Durham, NC) or disk diffusion method following CLSI guidelines. Isolates were tested using the Acuitas® MDRO Gene Test ( ...
Chromosome Locations of the MYB Related Genes, AMYB and
... 8q24-^>8qter (Fig. 2A, Lane 8). Thus, the results summarized in Fig. 1 give a regional localization of AMYB to region Seen—» 8q24. In order to refine the regional localization, an additional pair of hybrids derived from leukemias carrying a t(8;21)(q22;q22) (15-17, 20) was tested. The 8q- hybrid ...
... 8q24-^>8qter (Fig. 2A, Lane 8). Thus, the results summarized in Fig. 1 give a regional localization of AMYB to region Seen—» 8q24. In order to refine the regional localization, an additional pair of hybrids derived from leukemias carrying a t(8;21)(q22;q22) (15-17, 20) was tested. The 8q- hybrid ...
Looping versus linking: toward a model for long
... whereupon expression from the majority of loci is prevented by the formation of repressive chromatin structures. Tissue-specific LCRs would then be required to prevent such structures from forming at the minority of loci from which expression is required for the particular cell type. Essentially, ho ...
... whereupon expression from the majority of loci is prevented by the formation of repressive chromatin structures. Tissue-specific LCRs would then be required to prevent such structures from forming at the minority of loci from which expression is required for the particular cell type. Essentially, ho ...
Identification of an antibacterial protein by functional screening of a
... To precisely identify the gene(s) responsible for antibacterial activity, p112C was subjected to in vitro transposon mutagenesis. Two mutants, 112CTM3D10 and 112CTM1H7, which had lost antibacterial activity and had a single transposon insertion were obtained. In 112CTM3D10, the transposon was insert ...
... To precisely identify the gene(s) responsible for antibacterial activity, p112C was subjected to in vitro transposon mutagenesis. Two mutants, 112CTM3D10 and 112CTM1H7, which had lost antibacterial activity and had a single transposon insertion were obtained. In 112CTM3D10, the transposon was insert ...
COMPUTATIONAL BIOLOGY
... from entry X01714, the one that describes its bacterial homologue. The top part of the entry follows the general information keywords order: LOCUS, ACCESSION, DEFINITION and VERSION The KEYWORD line, which is supposed to list readily relevant and searchable terms, is empty for entry U90223. Unfortun ...
... from entry X01714, the one that describes its bacterial homologue. The top part of the entry follows the general information keywords order: LOCUS, ACCESSION, DEFINITION and VERSION The KEYWORD line, which is supposed to list readily relevant and searchable terms, is empty for entry U90223. Unfortun ...
Lecture 14 - The Chromosomal Basis of Inheritance
... • Linked genes are genes that tend to be inherited together – They are located very close to each other on a chromosome – They are unlikely to be separated during homologous recombination and independent assortment Homologous recombination during meiosis “can cause alleles previously on the same chr ...
... • Linked genes are genes that tend to be inherited together – They are located very close to each other on a chromosome – They are unlikely to be separated during homologous recombination and independent assortment Homologous recombination during meiosis “can cause alleles previously on the same chr ...
Gill: Gene Regulation II
... sites, preventing/repelling the binding of – The RNA polymerase machinery – Activating transcription factors (including via competitive binding) • Some transcription factors have stereotypical roles as activators or repressors. Likely many can do both (in different contexts). • DNA can be bent into ...
... sites, preventing/repelling the binding of – The RNA polymerase machinery – Activating transcription factors (including via competitive binding) • Some transcription factors have stereotypical roles as activators or repressors. Likely many can do both (in different contexts). • DNA can be bent into ...
Proteorhodopsin Phototrophy Promotes Survival of Marine
... bacteria, as has recently been suggested for other marine bacteria [2,24,25]. Lateral gene transfer may involve mobile genetic elements since transposase genes are found flanking the PR, crtEIBY, and blh genes in both BAA-1116 and AND4 (Figure 2). The transposase gene closest to the PR gene in AND4 ...
... bacteria, as has recently been suggested for other marine bacteria [2,24,25]. Lateral gene transfer may involve mobile genetic elements since transposase genes are found flanking the PR, crtEIBY, and blh genes in both BAA-1116 and AND4 (Figure 2). The transposase gene closest to the PR gene in AND4 ...
Gene targeting in mice - University of Utah Health Care
... insertion of the targeting vector at various random sites in the genome, other than the target locus, would be far more common. We therefore proposed to use selection to eliminate cells that do not contain the desired targeted homologous recombination products. The first step of this scheme required ...
... insertion of the targeting vector at various random sites in the genome, other than the target locus, would be far more common. We therefore proposed to use selection to eliminate cells that do not contain the desired targeted homologous recombination products. The first step of this scheme required ...
PDF - WashU Epigenome Browser
... After juxtaposing on RefSeq genes, intergenic regions are hidden, and only data over gene bodies are shown. When running juxtaposition, the browser can be zoomed and scrolled as normal. The juxtaposition function is applicable for other types of positional annotation data in addition to genes. To ru ...
... After juxtaposing on RefSeq genes, intergenic regions are hidden, and only data over gene bodies are shown. When running juxtaposition, the browser can be zoomed and scrolled as normal. The juxtaposition function is applicable for other types of positional annotation data in addition to genes. To ru ...
Chapter 14: Mendel and the Gene Idea
... Concept 14.3 Inheritance patterns are often more complex than those predicted by simple Mendelian genetics ...
... Concept 14.3 Inheritance patterns are often more complex than those predicted by simple Mendelian genetics ...
Bacterial Genomics
... Using Ka/Ks values as a proxy for level of drift 1. Because point mutations that cause amino acid replacements are often deleterious, the rate of nonsynonymous changes (Ka) is expected to be less than the rate of synonymous substitutions (Ks) in functional genes. 2. An increased level of drift, pro ...
... Using Ka/Ks values as a proxy for level of drift 1. Because point mutations that cause amino acid replacements are often deleterious, the rate of nonsynonymous changes (Ka) is expected to be less than the rate of synonymous substitutions (Ks) in functional genes. 2. An increased level of drift, pro ...
Microarray Image Data Analysis
... category i, each pattern consists of M redundant features, e.g., a microarray can be represented as a pattern consisting of 13574 features corresponding to 13574 effected genes. The goal is to select a small subset of features for “Recognition” ...
... category i, each pattern consists of M redundant features, e.g., a microarray can be represented as a pattern consisting of 13574 features corresponding to 13574 effected genes. The goal is to select a small subset of features for “Recognition” ...
Combining Microarrays and Biological Knowledge for
... network construction from microarray data is that while the gene network contains a large number of genes, the information contained in gene expression data is limited by the number of microarrays, their quality, the experimental design, noise, and measurement errors. Therefore, estimated gene netwo ...
... network construction from microarray data is that while the gene network contains a large number of genes, the information contained in gene expression data is limited by the number of microarrays, their quality, the experimental design, noise, and measurement errors. Therefore, estimated gene netwo ...
06MicrobialGenetExamII
... that appears almost identical to the common nonpathogenic strain of E.coli that is normally found in our intestines. When culturing the bacteria, scientists found that the pathogenic strain is resistant to penicillin, a problem that delayed effective treatment for some patients. Additionally, rather ...
... that appears almost identical to the common nonpathogenic strain of E.coli that is normally found in our intestines. When culturing the bacteria, scientists found that the pathogenic strain is resistant to penicillin, a problem that delayed effective treatment for some patients. Additionally, rather ...