Association of Apolipoprotein E Alleles with Susceptibility to Age
... Apo E plays a pivotal role in lipid transportation and is known to be one of the drusen making elements (21). APOE is a polymorphic gene and makes a large number of different apo E isoforms of which the apoE2, apoE3 and apoE4, encoded by ε2, ε3 and ε4 allelic variants are the main isoforms identifie ...
... Apo E plays a pivotal role in lipid transportation and is known to be one of the drusen making elements (21). APOE is a polymorphic gene and makes a large number of different apo E isoforms of which the apoE2, apoE3 and apoE4, encoded by ε2, ε3 and ε4 allelic variants are the main isoforms identifie ...
A set reduction and pattern matching problem motivated by Allele
... primer pair). This pair is designed from a set of template sequences so they flank the desired region. When the primers bind to the DNA they enable amplification of the flanked region by a DNA polymerase which extends the primer sequence and creates two copies of the flanked region. This process is ...
... primer pair). This pair is designed from a set of template sequences so they flank the desired region. When the primers bind to the DNA they enable amplification of the flanked region by a DNA polymerase which extends the primer sequence and creates two copies of the flanked region. This process is ...
Experimental matings: Df/wt x wt
... Among many animals species, females retain sperm within specific regions of their reproductive tract (often chambers called storage organs) for various periods of time between the start of sperm transfer and when sperm leave the reproductive tract (Bloch Qazi et al., 2003). This phenomenon is cal ...
... Among many animals species, females retain sperm within specific regions of their reproductive tract (often chambers called storage organs) for various periods of time between the start of sperm transfer and when sperm leave the reproductive tract (Bloch Qazi et al., 2003). This phenomenon is cal ...
The SELF-PRUNING gene of tomato regulates
... indeterminate vegetative apex generates leaves on its flanks before changing to an indeterminate floral apex that extends indefinitely (arrow) as flowers are now generated in succession upon its flanks. Side arrows indicate coflorescences arising in the axils of cauline leaves and black circles repr ...
... indeterminate vegetative apex generates leaves on its flanks before changing to an indeterminate floral apex that extends indefinitely (arrow) as flowers are now generated in succession upon its flanks. Side arrows indicate coflorescences arising in the axils of cauline leaves and black circles repr ...
Level 3, 2004
... the order, and how many of them are linked together, determines what the protein is and does. These amino acid sequences are coded for by sequenced triplets of bases on the DNA. If the DNA has a large part of the sequence replaced by another sequence, then it usually forms a completely different pro ...
... the order, and how many of them are linked together, determines what the protein is and does. These amino acid sequences are coded for by sequenced triplets of bases on the DNA. If the DNA has a large part of the sequence replaced by another sequence, then it usually forms a completely different pro ...
msb145697-sup-0001-Supp_Info
... as the fraction goes up, with around 20% for 5% of expected fraction and less than 10% for 7.5% of expected fraction. B Comparison of spectral counting data with the R/P data and ribosomal profiling data (Li et al, 2014) for the proteome fraction of ribosomal proteins. The ribosomal protein fraction ...
... as the fraction goes up, with around 20% for 5% of expected fraction and less than 10% for 7.5% of expected fraction. B Comparison of spectral counting data with the R/P data and ribosomal profiling data (Li et al, 2014) for the proteome fraction of ribosomal proteins. The ribosomal protein fraction ...
Paper - John Innes Centre
... might have little or no disease because they were not successfully infected. On the other hand, leaf sections from an individual with a resistant genotype should never be highly diseased. The wheat– M. graminicola interaction is a difficult disease to work with; therefore, perfect reproducibility be ...
... might have little or no disease because they were not successfully infected. On the other hand, leaf sections from an individual with a resistant genotype should never be highly diseased. The wheat– M. graminicola interaction is a difficult disease to work with; therefore, perfect reproducibility be ...
ARF-Aux/IAA interactions through domain III/IV are not strictly
... gene expression is suggested from studies with TPL, which likely plays a role in inducing a repressive chromatin state through posttranslational histone modifications (i.e., histone deacetylation and methylation/demethylation) on auxin response genes.9 Other results suggest that the reversal of this ...
... gene expression is suggested from studies with TPL, which likely plays a role in inducing a repressive chromatin state through posttranslational histone modifications (i.e., histone deacetylation and methylation/demethylation) on auxin response genes.9 Other results suggest that the reversal of this ...
Molecular pathogenesis of liver adenomas and FNH - HAL
... these tumors. Novel markers specific to these subtypes have been developed, implicating a potential for use in clinical practice. In this review, we will focus on the recent progress in understanding of the molecular mechanisms in these two hepatocellular tumors. 1 - Focal Nodular Hyperplasia (FNH) ...
... these tumors. Novel markers specific to these subtypes have been developed, implicating a potential for use in clinical practice. In this review, we will focus on the recent progress in understanding of the molecular mechanisms in these two hepatocellular tumors. 1 - Focal Nodular Hyperplasia (FNH) ...
Protein sequence comparisons show that the
... This set of sequence comparisons was completed by an unexpected finding: the absent herpesvirus Motif 3 is present in the N-terminal halves of the herpesvirus dUTPase sequences. The N-terminal portions of the HSV-1, VZV and EBV dUTPases, of some 200 residues, show little overall sequence similarity ...
... This set of sequence comparisons was completed by an unexpected finding: the absent herpesvirus Motif 3 is present in the N-terminal halves of the herpesvirus dUTPase sequences. The N-terminal portions of the HSV-1, VZV and EBV dUTPases, of some 200 residues, show little overall sequence similarity ...
CTLA-4 gene expression is influenced by promoter and
... murine cytolytic T-cell cDNA library,5 and the gene encoding the molecule is in humans located on chromosome 2q33-q34, 25–150 kilobases from the CD28 gene, with which it shares extensive sequence homology.6 Expression of CTLA-4 is mainly restricted to CD4+ and CD8+ activated T-lymphocyte subsets,7 b ...
... murine cytolytic T-cell cDNA library,5 and the gene encoding the molecule is in humans located on chromosome 2q33-q34, 25–150 kilobases from the CD28 gene, with which it shares extensive sequence homology.6 Expression of CTLA-4 is mainly restricted to CD4+ and CD8+ activated T-lymphocyte subsets,7 b ...
Presence of a mitochondrial-type 70
... DNA of T. vaginalis. Among them, five were of endoplasmic reticulum type, one of cytosolic type (data not shown) and two exhibited eubacterial features. Preliminary phylogenetic analysis demonstrated that the latter two sequences emerged together within the cluster of mitochondrial sequences. To mak ...
... DNA of T. vaginalis. Among them, five were of endoplasmic reticulum type, one of cytosolic type (data not shown) and two exhibited eubacterial features. Preliminary phylogenetic analysis demonstrated that the latter two sequences emerged together within the cluster of mitochondrial sequences. To mak ...
The Origin of Subfunctions and Modular Gene Regulation
... similarly. We further assume the presence of tissue-specific transcription factors (TFB and TFC), expressed in a complementary manner (one in each tissue) with respect to the ancestral expression of TFA. The existence of these tissue-specific transcription factors provides the essential setting in w ...
... similarly. We further assume the presence of tissue-specific transcription factors (TFB and TFC), expressed in a complementary manner (one in each tissue) with respect to the ancestral expression of TFA. The existence of these tissue-specific transcription factors provides the essential setting in w ...
Bioinformatics: Bringing it all together
... Wisconsin package, the grandfather of molecular-biology packages (now sold by Accelrys), had to work with UNIX-based systems. Although these systems are still preferred by some, users can now point-and-click their way through a wide range of tasks on ordinary desktop computers. Another trend is the ...
... Wisconsin package, the grandfather of molecular-biology packages (now sold by Accelrys), had to work with UNIX-based systems. Although these systems are still preferred by some, users can now point-and-click their way through a wide range of tasks on ordinary desktop computers. Another trend is the ...
Classification by Nearest Shrunken Centroids and Support Vector
... The group centroid x̄gk for gene g and class k is compared to the overall centroid x̄g by x̄gk = x̄g + mk (sg + s0) dgk , where sg is the pooled within-class standard deviation of gene g and s0 is an offset to guard against genes with low expression levels. Shrinkage: Each dgk is reduced by ∆ in abs ...
... The group centroid x̄gk for gene g and class k is compared to the overall centroid x̄g by x̄gk = x̄g + mk (sg + s0) dgk , where sg is the pooled within-class standard deviation of gene g and s0 is an offset to guard against genes with low expression levels. Shrinkage: Each dgk is reduced by ∆ in abs ...
Canine CD34: Cloning of the cDNA and Evaluation
... BMMC (2 X 107/mL) were stained with RpacaCD34 as described above, resuspended in PBSl28 horse serum, and sorted on a FACStar (Becton Dickinson). Lineage depletion of canine BMMC was performed with the following MoAbs: JD3 (anti-CD8):’ 1 E4 (antiCD4),3’ Tuk4 (antimonocyte; DAKO, Glostrup, Denmark), a ...
... BMMC (2 X 107/mL) were stained with RpacaCD34 as described above, resuspended in PBSl28 horse serum, and sorted on a FACStar (Becton Dickinson). Lineage depletion of canine BMMC was performed with the following MoAbs: JD3 (anti-CD8):’ 1 E4 (antiCD4),3’ Tuk4 (antimonocyte; DAKO, Glostrup, Denmark), a ...
ChromatinDB: a database of genome-wide
... ChromatinDB was used to visualize histone modification data for 135 yeast promoters that are targeted by the Gcn5 histone acetyltransferase. These genes were chosen as each were significantly bound by Gcn5 (P50.01) based on a previous ChIP microarray study (Robert et al., 2004). A portion of the res ...
... ChromatinDB was used to visualize histone modification data for 135 yeast promoters that are targeted by the Gcn5 histone acetyltransferase. These genes were chosen as each were significantly bound by Gcn5 (P50.01) based on a previous ChIP microarray study (Robert et al., 2004). A portion of the res ...
Contig annotation tool CAT robustly classifies assembled
... are summed for each taxon (ΣBtaxon), where the taxonomic annotations of T and all of its parents in the taxonomic lineage are considered. For example, if the top hits of a given ORF share a LCA T at the taxonomic level of family, then their average bitscore value B would also be considered in the ΣB ...
... are summed for each taxon (ΣBtaxon), where the taxonomic annotations of T and all of its parents in the taxonomic lineage are considered. For example, if the top hits of a given ORF share a LCA T at the taxonomic level of family, then their average bitscore value B would also be considered in the ΣB ...
PDF File
... hand, it was difficult to envision how RNA could pack efficiently in this manner given the regular architecture of RNA helices, its limited side chain diversity, and the expectation that RNA’s negative charge would repel the close approach of other strands. Moreover, because RNA packing had not been ...
... hand, it was difficult to envision how RNA could pack efficiently in this manner given the regular architecture of RNA helices, its limited side chain diversity, and the expectation that RNA’s negative charge would repel the close approach of other strands. Moreover, because RNA packing had not been ...
lecture_07(LP)
... What this course is about From Lecture 1 Inheritance how is genetic information read within cells? how are traits transmitted to progeny? how are unique physical traits determined by genes? ...
... What this course is about From Lecture 1 Inheritance how is genetic information read within cells? how are traits transmitted to progeny? how are unique physical traits determined by genes? ...
Deciphering the role of DNA methylation in multiple sclerosis
... histone leads to decompression of chromatin and upregulates transcription [3]. Micro-RNAs are single stranded, small in nucleotide amount RNAs, which do not encode any proteins. They can affect gene expression, acting after gene transcription and their expression depends on the interaction with the ...
... histone leads to decompression of chromatin and upregulates transcription [3]. Micro-RNAs are single stranded, small in nucleotide amount RNAs, which do not encode any proteins. They can affect gene expression, acting after gene transcription and their expression depends on the interaction with the ...
to the complete text - David Moore`s World of Fungi
... value of around 30% if gene w is to the left of gene x. However, remembering the variability expected in normal experiments, we would have to analyze a large number of progeny, probably from several hundred to a couple of thousand, if we want to obtain a believable result. But there is a better way. ...
... value of around 30% if gene w is to the left of gene x. However, remembering the variability expected in normal experiments, we would have to analyze a large number of progeny, probably from several hundred to a couple of thousand, if we want to obtain a believable result. But there is a better way. ...
Volume 11 - Número 6 - Novembro / Dezembro de 2001
... During formation of microfibrils, fibrillin monomers probably assemble together forming what is seen by electron microscopy as beaded strings. They subsequently may interact with other microfibrillar components into thread-like filaments which will give rise to macroaggregates with or without elasti ...
... During formation of microfibrils, fibrillin monomers probably assemble together forming what is seen by electron microscopy as beaded strings. They subsequently may interact with other microfibrillar components into thread-like filaments which will give rise to macroaggregates with or without elasti ...
Metabolic rate depression in animals
... regulatory control that are conserved across phylogenetic lines and that are broadly applied to the control of multiple cell functions. One such mechanism is reversible protein phosphorylation which is now known to contribute to the regulation of fuel metabolism, to ion channel arrest, and to the su ...
... regulatory control that are conserved across phylogenetic lines and that are broadly applied to the control of multiple cell functions. One such mechanism is reversible protein phosphorylation which is now known to contribute to the regulation of fuel metabolism, to ion channel arrest, and to the su ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.