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Chapter 21: Molecular Basis of Cancer
Chapter 21: Molecular Basis of Cancer

... denaturing HPLC from Transgenomic ...
bio12_sm_07_5
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... affect the activity of a peptide depending on the peptide’s structure and function. 9. (a) The CAG trinucleotide is the repeated sequence linked to Huntington’s disease. (b) The probable onset of Huntington’s occurs between 30 and 70 repeats. (c) The more repeats there are, the greater the effect of ...
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... the late steps of the pathway (Piggot and Hoch, 1985). An argE gene has been located by sequencing the B. subtilis genome (Kunst et al., 1997) but its relation with the cyclic pathway of arginine biosynthesis in this bacterium (Figure 1) remains to be elucidated; the regulatory gene ahrC encoding th ...
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... missing chromosomes or chromosome fragments, visible under a microscope when a cell’s DNA is stained, can cause conditions such as Down syndrome. They have also tied scores of diseases to molecular misspellings: mutations in individual bases that make up the DNA in a gene. But, as Lupski discovered, ...
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High-Resolution Array-Based Comparative Genomic Hybridization
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... borderline melanocytic lesions where prolonged follow-up over many years may be required to ensure benign biologic behavior (ie, absence of metastasis). Gene expression profiling experiments use mRNA harvested from fresh tumor tissue, from which cDNAs are produced and used for hybridization. They ha ...
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... would be the genotype and phenotype of the F1 and the F2 generations? 6. In guinea pigs, rough coat is due a dominant gene (R) and smooth to its recessive allele (r). Short hair is dependant upon a dominant gene (L), and long hair upon its recessive allele (l). Give the phenotype and genotype and th ...
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... • It was later discovered that many proteins are actually composed of more than one polypeptide and it was proposed that each polypeptide required a separate gene. • Researchers in the last few years have discovered that at least some genes are not that straightforward. One gene may lead to a single ...
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The nucleotide sequence of the tnpA gene completes the sequence
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... a reading frame that is not present in Tn501 (41). The reading frames urf-1 and urf-2 have not been ascribed a function. The exact positions of gene boundaries and other features are given in Table 1, as are references to the sequence data. The transposon is 8355 nucleotide pairs in length. ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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