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Continuous Representations of Time Series Gene Expression Data
Continuous Representations of Time Series Gene Expression Data

... sampled non-uniformly, and measure biological processes that exhibit temporal variation. In many applications, researchers may face the problem of reconstructing unobserved gene expression values. Values may not have been observed for two reasons. First, errors may occur in the experimental process ...
Leukaemia Section t(7;14)(p15;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section t(7;14)(p15;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... No fusion protein. Overexpression of HOXA genes as a result of the translocation with TCRD was expected, as it was demonstrated to be the case in HOXA-TCRB TALLs. However this case had a CALM-AF10 fusion in the same leukemic clone. CALM-AF10 is already ...
Regulatory sequences
Regulatory sequences

... Recruitment of CIITA to MHC-II promoters. A prototypical MHC-II promoter (HLA-DRA) is represented schematically with the W, X, X2, and Y sequences conserved in all MHC-II, Ii, and HLA-DM promoters. RFX, X2BP, NF-Y, and an as yet undefined W-binding protein bind cooperatively to these sequences and a ...
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... challenging task. Existing diagnostic classes are often heterogeneous and include diseases with different clinical courses, therapeutic response and metastatic potential. In just the last few recent years, DNA microarrays have become almost ubiquitous in biological research. Since cancer is a geneti ...
Chapter 13 Chromatin Structure and its Effects on
Chapter 13 Chromatin Structure and its Effects on

... Chromatin is required for specificity • With DNA, RNA polymerase III transcribes both well ...
2011 - Barley World
2011 - Barley World

... a. The heritability of stem length in all barley populations will be 0 b. If you did a better job of controlling environmental variation in a subsequent experiment involving the A x B population, the heritability might increase c. Heritability is so difficult to calculate that it is of little practi ...
Nutritional properties of Meat
Nutritional properties of Meat

... • Dietary intake of omega 3 PUFAs influences the expression levels of many genes controlling resistance to endogenous free radicals and ABeta protein balance ...
Chapter 10: Genes and Chromosomes
Chapter 10: Genes and Chromosomes

... A translocation occurs when part of one chromosome ______________________ and attaches to another, nonhomologous chromosome ...
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... polyA signal finder (Tabaska and Zhang, 1999). The background sequence statistics were worked out on a set of 764 high throughput genomic sequences of human genome. We considered only completed sequences with size larger than 100 kb. Total size of these genomic sequences is ∼100 Mb. The test set. Fo ...
Genes and Traits
Genes and Traits

...  Genetics is the study of how traits ...
251 Lab 2 Chrisine
251 Lab 2 Chrisine

... Q17: From the Table of Contents, select “Allelic Variants”, read this section, and answer the following question: What is the molecular genetic basis for the disease? Explain how repeat sequence variation is responsible for this disease. The nucleotide sequence CAG is located in the region coding of ...
video slide - SharpSchool
video slide - SharpSchool

... 1 A small ribosomal subunit binds to a molecule of mRNA. In a prokaryotic cell, the mRNA binding site on this subunit recognizes a specific nucleotide sequence on the mRNA just upstream of the start codon. An initiator tRNA, with the anticodon UAC, base-pairs with the start codon, AUG. This tRNA car ...
video slide
video slide

... • Most eukaryotic genes and their RNA transcripts have long noncoding stretches of nucleotides that lie between coding regions • These noncoding regions are called intervening sequences, or introns • The other regions are called exons because they are eventually expressed, usually translated into am ...
Roles of cell-wall invertases and monosaccharide transporters in the
Roles of cell-wall invertases and monosaccharide transporters in the

... galactose, xylose, and mannose, but not fructose. It accounts for the majority of the AtSTP activity in vegetative tissues and its activity is markedly repressed by treatment with exogenous sugars. These observations are consistent with a role in the retrieval of cell-wall-derived sugars, for exampl ...
Searching for Genes
Searching for Genes

... All branches on the tree of life share common roots. One way to study those roots is to look to DNA sequences. So, when the Roberts lab began studying the evolution of cellulose synthesis, one place they looked was at the available DNA sequence information. Even now, as they expand their studies to ...
PDF - Biology of Sex Differences
PDF - Biology of Sex Differences

... Table S1). These datasets report gene expression levels in a variety of tissues (Additional file 2: Figure S1) based on microarray expression profiling using a variety of platforms. The goal was to obtain as much data as possible, to avoid any bias that might be specific to an individual microarray ...
SURVEY AND SUMMARY Origins of tmRNA: the
SURVEY AND SUMMARY Origins of tmRNA: the

... associated with Small protein B (SmpB). tmRNA is a hybrid molecule carrying out both transfer and messenger RNA activities, and its total length varies between about 260 and 430 nucleotides, depending on the cell species (Figure 4). It is always aminoacylated by alanine. As for SmpB, its topology ma ...
DNA Analysis
DNA Analysis

... • Alphabet of bases = {A,T,C,G}  not uniformly distributed in any sequence and the composition vary within and between sequences ...
Basic molecular genetics for epidemiologists
Basic molecular genetics for epidemiologists

... come into the epidemiological scene with plenty of new sophisticated concepts and methodological issues. This fact led the editors of the journal to offer you a glossary of terms commonly used in papers applying genetic methods to health problems to facilitate your “walking” around the journal issue ...
Bio290-08-Week 9
Bio290-08-Week 9

... Dr. Michael Schlador 3. Follow-up: the Use of Microarray Analysis in Chemotherapeutics 4. Preview of Chapter 15 & ...
BIOL 202 LAB 3 Genetics
BIOL 202 LAB 3 Genetics

... muscles, and note whether you have a bent or a straight little finger. Long palamar muscle: When a person is homozygous for a certain recessive gene (l), he or she has a long palamar muscle, which can be detected by examination of the tendons that run over the inside of the wrists. Clench your fists ...
Comprehension Questions
Comprehension Questions

... Comprehension Questions: Isolating Total DNA from Specimen Tissue 1. Where does DNA reside? ...
Sarah Justvig (`13)
Sarah Justvig (`13)

... protein of Ewing’s sarcoma, shares with ERG and ETV1 identification as a Class I ETS factor. The three are more than 60% identical and 80% homologous in their amino acid sequences. YK-4-279 has been identified as a small molecule inhibitor of EWS/FLI1 oncoprotein in Ewing’s sarcoma. Given the strong ...
Transcription regulation of the Escherichia coli pcnB gene coding for
Transcription regulation of the Escherichia coli pcnB gene coding for

... There are two major eVectors of the stringent response. The Wrst one is a couple of two speciWc nucleotides, guanosine tetraphosphate (ppGpp) and guanosine pentaphosphate (pppGpp), collectively called (p)ppGpp and rapidly produced in response to variety of physico-chemical and nutritional stresses ( ...
Rosetta Biosoftware and GeneGo working together Resolver system
Rosetta Biosoftware and GeneGo working together Resolver system

... The user launches MetaCore from the Resolver system and behind the scenes MetaCore uploads their experimental data and displays a page in which users can visualize their data in (predrawn) maps or build networks on the fly ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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